Results: 19

Características de los pacientes infectados por el coronavirus 2019 en China y dinámica de su transmisión temprana

Sensitivity of the Wondfo One Step COVID-19 test using serum samples

Clinics; 75 (), 2020

SARS-CoV-2 diagnostic diary: from rumors to the first case. Early reports of molecular tests from the military research and diagnostic institute of Rio de Janeiro

Mem. Inst. Oswaldo Cruz; 115 (), 2020
Corona virus disease (COVID-19) presents a serious threat to global health. A historical timeline of early molecular diagnostics from government alert (January 22) (D) was presented. After in silico analysis, Brazilian Army Institute of Biology (IBEx-RJ) tested samples in house using real-time reverse tr...

In silico analysis of mismatches in RT-qPCR assays of 177 SARS-CoV-2 sequences from Brazil

Abstract INTRODUCTION: Quantitative reverse transcription polymerase chain reaction (RT-qPCR) can detect the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) in a highly specific manner. However, a decrease in the specificity of PCR assays for their targets may lead to false negative result...

A novel Betacoronavirus characterised in collared peccaries from the Rio de Janeiro Zoo (Brazil) killed by unknown disease

Mem. Inst. Oswaldo Cruz; 115 (), 2020
In an enclosure with nine collared peccaries (Pecari tajacu) from the Rio de Janeiro city Zoo, Brazil, one specimen was found dead and two others developed prostration, apathy and dehydration, resulting on its death. Necropsy of two animals pointed to pulmonary and renal damage. Histological examination ...

Genomic and phylogenetic characterisation of an imported case of SARS-CoV-2 in Amazonas State, Brazil

Mem. Inst. Oswaldo Cruz; 115 (), 2020
A new coronavirus [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] is currently causing a life-threatening pandemic. In this study, we report the complete genome sequencing and genetic characterisation of a SARS-CoV-2 detected in Manaus, Amazonas, Brazil, and the protocol we designed to gen...

Detección de COVID -19 (SARS-CoV-2) mediante la saliva: una alternativa diagnóstica poco invasiva

La nueva enfermedad por coronavirus, también denominada COVID 19 es la última enfermedad infecciosa de preocupación internacional. Originada en Wuhan, China, se extendió a nivel mundial, resultando en la pandemia 2019-2020 y una Emergencia de Salud Pública de Preocupación Internacional (ESPII) seg...

Bases genéticas y moleculares del COVID-19 (SARS-CoV-2): mecanismos de patogénesis y de respuesta inmune

A fines de diciembre de 2019, un nuevo coronavirus (SARS-CoV-2) fue identificado como el agente causal de una nueva enfermedad respiratoria llamada COVID-19 por la OMS. Sus síntomas incluyen fiebre, tos seca y dificultad respiratoria. Estos síntomas en general son leves, aunque, pueden ser fatales en a...

The halo sign as a chest computed tomography finding of COVID-19