RESUMO A transfusão de concentrado de plaquetas é prática comum para prevenção de sangramento espontâneo ou decorrente de procedimentos invasivos; sabe-se que a transfusão de componentes alogênicos do sangue se associa a aumento da mortalidade e piora do desfecho clínico. A força do coágulo é...
Trastornos de la Coagulación Sanguínea/diagnóstico,
Trastornos de la Coagulación Sanguínea/etiología,
Células de la Médula Ósea/patología,
Broncoscopía/métodos,
Fibrinógeno/metabolismo,
Unidades de Cuidados Intensivos,
Persona de Mediana Edad,
Choque Séptico/complicaciones,
Tromboelastografía/métodos,
Trombocitopenia/etiología,
Trombocitopenia/fisiopatología
Abstract The goal of this study was to analyze cytotoxicity, genotoxicity and mutagenicity to bone marrow cells of mice of nature identical synthetic flavorings, passion fruit and strawberry, and artificial synthetic flavorings, vanilla, chocolate, tutti-frutti and cookie, at doses 0.5; 1.0; 2.0; 5.0 and...
Abstract Handroanthus impetiginosus has long been used in traditional medicine and various studies have determined the presence of bioactive chemical compounds and potential phytotherapeutics. In this study, the genotoxicity of the lyophilized tincture of H. impetiginosus bark (THI) was evaluated in mous...
BACKGROUND Chagas disease is a public health problem caused by infection with the protozoan Trypanosoma cruzi. There is currently no effective therapy for Chagas disease. Although there is some evidence for the beneficial effect of bone marrow-derived cells in chagasic disease, the mechanisms underlying...
ABSTRACT The aim of this study was to evaluate the possible protective of C. guianensis oil against MMC and CP, which are direct- and indirect-acting chemical mutagens, using the micronucleus test. Three experiments were performed. First the C. guianensis oil was co-administered to mice at doses of 250, ...
O objetivo deste estudo foi comparar o potencial osteogênico das células tronco mesenquimais extraídas da medula óssea (CTM-MO) com as do tecido adiposo (CTM-AD) de cães adultos. As células foram caracterizadas fenotipicamente quanto à expressão de CD29, CD90, CD34 e CD45 e submetidas à diferenc...
La diabetes mellitus (DM) crónica se asocia con reducción en el contenido mineral óseo (osteopenia y osteoporosis). El objetivo de este trabajo fue evaluar la acción del ranelato de estroncio (RaSr) administrado por vía oral a animales control y diabéticos, sobre el potencial osteogénico de célul...
Abstract The aim of this study was to compare potential aspects of periapical lesion formation in hypertensive and normotensive conditions using hypertensive (BPH/2J) and wild-type control (BPN/3J) mice. The mandibular first molars of both strains had their dental pulp exposed. At day 21 the mice were eu...
Células de la Médula Ósea/patología,
Ensayo de Inmunoadsorción Enzimática,
Hipertensión/complicaciones,
Hipertensión/patología,
Interleucina-1alfa/análisis,
Interleucina-1beta/análisis,
Enfermedades Periapicales/etiología,
Enfermedades Periapicales/patología,
Ligando RANK/análisis,
Valores de Referencia,
Fosfatasa Ácida Tartratorresistente,
Factores de Tiempo,
Factor de Necrosis Tumoral alfa/análisis,
Microtomografía por Rayos X
Abstract Ca3SiO5 is new cement based on the composition of Portland that has been developed to have superior physicochemical and biological properties. In a clinical evaluation, the cement did not appear to have cytotoxic properties and allowed for the proliferation of pulp cells and gingival fibroblasts...
Células de la Médula Ósea/efectos de los fármacos,
Compuestos de Calcio/toxicidad,
Supervivencia Celular/efectos de los fármacos,
Ensayo Cometa,
Ciclofosfamida/toxicidad,
Daño del ADN/efectos de los fármacos,
Ensayo de Materiales,
Pruebas de Micronúcleos,
Materiales de Recubrimiento Pulpar y Pulpectomía/toxicidad,
Ratas Wistar,
Reproducibilidad de los Resultados,
Silicatos/toxicidad,
Tejido Subcutáneo/efectos de los fármacos,
Factores de Tiempo
