Results: 47

Whole-exome sequencing in familial keratoconus: the challenges of a genetically complex disorder

Arq. bras. oftalmol; 82 (6), 2019
ABSTRACT Purpose: The underlying genetic causes of keratoconus are essentially unknown. Here, we conducted whole-exome sequencing in 2 Brazilian families with keratoconus. Methods: Whole-exome sequencing was performed on 6 keratoconus-affected individuals of 2 unrelated pedigrees from Southern Brazil. ...

Orthokeratology on patient with ectasic cornea

Rev. bras. oftalmol; 78 (5), 2019
Abstract A 26-year-old man, single, business student, reveals a ectasic cornea during corneal topography exam. Among some procedures, the patient chose Orthokeratology to do a corneal reshape and got successfully a good visual acuity, going against the most authors guidance....

Evaluation of corneal layers and anterior sclera in patients with primary Sjögren's syndrome

Arq. bras. oftalmol; 82 (4), 2019
ABSTRACT Purpose: We aimed to compare the thickness of anterior sclera, corneal layers, and pre-ocular tear film between patients with primary Sjögren's syndrome and healthy individuals. Methods: Fifty-one patients with primary Sjögren's syndrome and 41 healthy control participants were recruited in ...

Investigating the effect of intracameral cefuroxime on oxidative stress and apoptosis in the rat cornea

Arq. bras. oftalmol; 82 (4), 2019
ABSTRACT PURPOSE: We examined the effect of intracameral administration of cefuroxime on oxidative stress and endothelial apoptosis in rat corneal tissue. METHODS: In total, 30 rats were divided into 3 groups of 10 rats each (intracameral administration of cefuroxime 0.1 mg/0.01 mL (cefuroxime group); ...

Effect of accelerated corneal crosslinking on ocular response analyzer waveform-derived parameters in progressive keratoconus

Arq. bras. oftalmol; 82 (1), 2019
ABSTRACT Purpose: To evaluate the effect of accelerated corneal crosslinking on corneal biomechanics with an ocular response analyzer in patients with progressive keratoconus. Methods: In this retrospective study, 50 eyes of 45 patients with progressive keratoconus who underwent accelerated corneal cro...

Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome

Arq. bras. oftalmol; 82 (1), 2019
ABSTRACT Purpose: The aim of the present study was to compare the severity of ocular and systemic findings among patients with primary Sjögren syndrome. Methods: The study followed a prospective controlled design and comprised two groups; the test group included 58 eyes of 58 patients newly diagnosed...

Anterior segment optical coherence tomography findings in type I Boston keratoprosthesis

Arq. bras. oftalmol; 81 (1), 2018
ABSTRACT Purpose: To report the results of high-resolution anterior segment optical coherence tomography of patients implanted with a type 1 Boston keratoprosthesis (KPro). Methods: The retrospective study cohort included 11 eyes of 11 patients (average age, 58.4 years; range, 34-83 years). All subject...

Treatment of perforated cornea with an autologous lamellar scleral graft: histologic findings

Arq. bras. oftalmol; 81 (1), 2018
ABSTRACT We report a case of central corneal perforation treated with an autologous lamellar scleral graft and histologic findings obtained after a subsequent penetrating keratoplasty. A corneal perforation within a large Pseudomonas ulcer in a 55-year-old male rigid gas permeable contact lens wearer was...

Depósitos de cálcio na córnea: estudo histopatológico

Rev. bras. oftalmol; 76 (6), 2017
Resumo Objetivo: Estudar, através do exame histopatológico, os depósitos de cálcio na córnea e suas diferentes formas de apresentação. Metodos: Estudo observacional, transversal, retrospectivo e descritivo de botões corneanos provenientes de ceratoplastia penetrante no período de 2006 a 2015. ...

Corneal biomechanical features in patients with ankylosing spondylitis

Arq. bras. oftalmol; 80 (5), 2017
ABSTRACT Purpose: To evaluate the corneal biomechanical features and central corneal thickness in ankylosing spondylitis patients and to evaluate correlations of these parameters with disease activity. Methods: The study included 51 patients diagnosed with ankylosing spondylitis (mean age, 40.80 ± 13....