RESUMO Objetivo O objetivo deste estudo foi investigar os efeitos agudos e crônicos da vareniclina no tecido pulmonar em um estudo experimental. Métodos Um total de 34 ratos foi alocado aleatoriamente em grupos de estudo (vareniclina) e controle. Assim, os ratos foram divididos em dois grupos: (i) gr...
Abstract Purpose To investigate the protective effect of Ganoderma lucidum on testicular torsion/detorsion (T/D)-induced ischemia-reperfusion (I/R) injury. Methods Thirty male Wistar albino rats were randomly categorized into 3 groups: Group 1: sham, Group 2 ( T/D): 2,5 hours of ischemia and 7 days of ...
Antioxidantes/farmacología,
Antioxidantes/uso terapéutico,
Catalasa/metabolismo,
Evaluación Preclínica de Medicamentos,
Malondialdehído/metabolismo,
Distribución Aleatoria,
Ratas Wistar,
Reishi/química,
Daño por Reperfusión/etiología,
Daño por Reperfusión/prevención & control,
Torsión del Cordón Espermático/complicaciones,
Torsión del Cordón Espermático/metabolismo,
Superóxido Dismutasa/metabolismo,
Testículo/irrigación sanguínea,
Testículo/patología,
Factor A de Crecimiento Endotelial Vascular/metabolismo,
Testículo/efectos de los fármacos
Abstract Purpose To evaluate renal histological changes by stereology and morphometry and analyze the main markers of oxidative stress in rats undergoing natural aging. Methods Seventy two Wistar rats were divided into six groups of 12 rats each, which were euthanized at 3, 6, 9, 12, 18, and 24 months ...
Abstract Background: Arterial hypertension is a precursor to the development of heart and renal failure, furthermore is associated with elevated oxidative markers. Environmental enrichment of rodents increases performance in memory tasks, also appears to exert an antioxidant effect in the hippocampus of...
Antioxidantes/metabolismo,
Presión Arterial,
Catalasa/metabolismo,
Ambiente,
Ventrículos Cardíacos/enzimología,
Vivienda para Animales,
Hipertensión Renovascular/inducido químicamente,
Hipertensión Renovascular/metabolismo,
Riñón/enzimología,
Peroxidación de Lípido,
Bulbo Raquídeo/enzimología,
Bulbo Raquídeo/metabolismo,
Estrés Oxidativo,
Carbonilación Proteica,
Ratas Endogámicas F344,
Superóxido Dismutasa/metabolismo
ABSTRACT Purpose: To investigate the potential associations between keratoconus and catalase rs1001179, superoxide dismutase 2 rs4880, and glutathione peroxidase 1 rs1050450 gene polymorphisms in a Turkish population. Methods: The study group included 121 unrelated keratoconus patients and 94 unrelate...
Estudios de Casos y Controles,
Catalasa/genética,
Frecuencia de los Genes,
Estudios de Asociación Genética,
Técnicas de Genotipaje,
Glutatión Peroxidasa/genética,
Queratocono/genética,
Reacción en Cadena de la Polimerasa,
Polimorfismo de Nucleótido Simple/genética,
Valores de Referencia,
Factores de Riesgo,
Superóxido Dismutasa/genética,
Turquía
Abstract Citrus fruit production occupies a place of considerable importance in the economy of the world including Pakistan. Tristeza disease caused by Citrus Tristeza Virus (CTV) exists in various forms that may or may not cause symptoms in the plants. The bioactive compounds and antioxidants are natur...
Antioxidantes/análisis,
Antioxidantes/clasificación,
Ácido Ascórbico/análisis,
Catalasa/análisis,
Citrus sinensis/química,
Citrus sinensis/enzimología,
Closterovirus/fisiología,
Flavonoides/análisis,
Peroxidasa/análisis,
Enfermedades de las Plantas/prevención & control,
Enfermedades de las Plantas/virología
Abstract Purpose: To examine the effects of Arrabidaa chica (Bignoniacea) extract, a native plant of the Amazon known as crajiru, on a 7,12-dimethyl-1,2-benzanthracene (DMBA)-induced breast cancer model in Wistar rats. Methods: We compared the response of breast cancer to the oral administration of A. ...
9,10-Dimetil-1,2-benzantraceno,
Antineoplásicos/farmacología,
Antineoplásicos/uso terapéutico,
Bignoniaceae/química,
Neoplasias de la Mama/diagnóstico por imagen,
Neoplasias de la Mama/tratamiento farmacológico,
Neoplasias de la Mama/patología,
Carcinógenos,
Carcinoma/diagnóstico por imagen,
Carcinoma/tratamiento farmacológico,
Carcinoma/patología,
Catalasa/análisis,
Fluorodesoxiglucosa F18,
Glutatión Peroxidasa/análisis,
Neoplasias Experimentales/tratamiento farmacológico,
Extractos Vegetales/farmacología,
Ratas Wistar,
Vincristina/farmacología,
Resultado del Tratamiento
The objective of this study was to evaluate the physiological quality allied to biochemical quality of lettuce seeds by germination and enzymes expression at 20, 25, 30, 35, 40 and 42ºC. Germination speed index and percentage of germination were estimated. Isoenzyme expressi...
Plant growth promotion by microorganisms may be a viable alternative to increase lettuce production through pathogens control and nutrients absorption increase. Trichoderma and Pseudomonasgenus are examples of widely studied microorganisms with the capacity to promote plant growth...
ABSTRACT Ducrosia anethifolia has been recommended as a remedy for neurological disorders. However, the anticonvulsant effects of D. anethifolia essential oil (DAEO) and its major constituent α-pinene have not yet been clarified. Methods: A rat model of pentylenetetrazole (PTZ)-induced convulsions ...
Anticonvulsivantes/química,
Anticonvulsivantes/farmacología,
Antioxidantes/análisis,
Antioxidantes/metabolismo,
Apiaceae/química,
Monoterpenos Bicíclicos/química,
Monoterpenos Bicíclicos/farmacología,
Catalasa/análisis,
Cromatografía Líquida de Alta Presión,
Peróxido de Hidrógeno/análisis,
Peroxidación de Lípido/efectos de los fármacos,
Malondialdehído/análisis,
Aceites Volátiles/química,
Aceites Volátiles/farmacología,
Estrés Oxidativo/efectos de los fármacos,
Pentilenotetrazol,
Peroxidasa/análisis,
Ratas Wistar,
Reproducibilidad de los Resultados,
Convulsiones/tratamiento farmacológico,
Convulsiones/metabolismo,
Resultado del Tratamiento,
Factores de Tiempo
