Abstract Curcumin is a plant-derived compound with polypharmacological properties that are hampered by its poor solubility, fast degradation, etc. Wound closure complications that follow tooth extraction are numerous, and relatively frequently additional treatment is needed to prevent unwanted process ch...
Abstract Aloe vera possesses a great therapeutic importance in traditional medicine. It has attracted the attention of modern medical fields due to its wide pharmacological applications. The bioactive substances in Aloe vera proved to have antioxidant, anti-inflammatory, antibacterial, and antiviral prop...
ABSTRACT Introduction Skeletal muscle injuries account for 10% to 50% of treadmill sports injuries. Insulin-like growth factor (IGF) is a family of polypeptides with both insulin-like anabolic and growth-promoting effects. Sports play a vital role in the recovery of skeletal muscle injuries. Objective...
ABSTRACT Objective: To observe clinically, in rabbits, the side effects of topical injection of subconjunctival cyclophosphamide, studying its role as an antifibrotic drug. Methods: Prospective study in 20 albino rabbits of New Zealand race. All rabbits were treated with cyclophosphamide, 10mg/ml in a ...
Ciclofosfamida/administración & dosificación,
Ciclofosfamida/farmacología,
Fibrosis/prevención & control,
Inyecciones Intraoculares,
Conjuntiva/efectos de los fármacos,
Cicatrización de Heridas/efectos de los fármacos,
Ciclofosfamida/efectos adversos,
Microscopía con Lámpara de Hendidura,
Fibroblastos/metabolismo,
Mitomicina/farmacología,
Fibroblastos/efectos de los fármacos,
Estudios Prospectivos
Abstract Background Dermabrasion is related with mechanical and surgical traumas on the skin; usually topical antiseptics and/or saline have been used for healing. Natural products for wound healing can also be used for abrasions, such as latex from Hevea brasiliensis. Objective This study aimed to eva...
In order to evaluate the potential of this formulation (P. lentiscus L. oil-based ointment) to heal wounds, experimental wounds were done on guinea pigs and efficiency was comparatively assessed against a reference ointment, Cicaderma®. Wound contraction was performed on days 5, 10 and 15. Tissue sectio...
Para promover la reparación y regeneración muscular, se han desarrollado diferentes estrategias, sin embargo, aún no existe un tratamiento único aceptado. Investigaciones relacionan los efectos terapéuticos de la miel en el proceso de cicatrización de heridas de diversas etiologías. Considerando l...
Breder, J S C;
Pires, A L R;
Azevedo, F F;
Apolinário, P P;
Cantaruti, T;
Jiwani, S I;
Moraes, Â M;
Consonni, S R;
Araújo, E P;
Adams, G G;
Saad, M J A;
Lima, M H M.
The use of specially designed wound dressings could be an important alternative to facilitate the healing process of wounds in the hyperglycemic state. Biocompatible dressings combining chitosan and alginate can speed up wound healing by modulating the inflammatory phase, stimulating fibroblast prolifera...
Alginatos/administración & dosificación,
Vendajes,
Materiales Biocompatibles/administración & dosificación,
Biomarcadores/sangre,
Proliferación Celular/efectos de los fármacos,
Quitosano/administración & dosificación,
Colágeno/efectos de los fármacos,
Diabetes Mellitus Experimental/fisiopatología,
Inflamación/prevención & control,
Ratones Endogámicos C57BL,
Factores de Tiempo,
Cicatrización de Heridas/efectos de los fármacos
A estimulação elétrica (EE) tem sido usada no tratamento de lesões crônicas apresentando resultados favoráveis no fechamento da lesão cutânea entre outras aplicações clínicas. No entanto, a literatura carece de estudos avaliando se os efeitos da EE no fechamento da lesão oral. Diante disso, t...
Abstract Purpose: To evaluate the in vivo response of photobiomodulation therapy associated with norbixin-based poly(hydroxybutyrate) membrane (PHB) in tenotomized calcaneal tendon. Methods: Thirty rats were randomly allocated to six groups (n=5 each): LED groups (L1, L2 and L3) and membrane + LED grou...
Tendón Calcáneo/efectos de los fármacos,
Tendón Calcáneo/efectos de la radiación,
Tendón Calcáneo/cirugía,
Carotenoides/farmacología,
Colágeno/farmacología,
Colágeno Tipo I/análisis,
Colágeno Tipo I/efectos de los fármacos,
Colágeno Tipo III/análisis,
Colágeno Tipo III/efectos de los fármacos,
Evaluación Preclínica de Medicamentos,
Fibroblastos/química,
Fibroblastos/efectos de los fármacos,
Hidroxibutiratos/farmacología,
Terapia por Luz de Baja Intensidad/métodos,
Prohibitinas,
Distribución Aleatoria,
Ratas Wistar,
Tendinopatía/radioterapia,
Tenotomía/métodos,
Cicatrización de Heridas/efectos de los fármacos,
Cicatrización de Heridas/efectos de la radiación
