Results: 108

Optimization of Diltiazem hydrochloride osmotic formulation using QBD approach

Abstract Diltiazem hydrochloride (DLH) is a calcium channel blocker useful for the treatment of angina pectoris, arrhythmia, and hypertension. DLH having a short half-life needs frequent administration for successful treatment but this poses a problem of poor patient compliance. These requirements are se...

Momento aductor de la cadera durante la marcha en adultos mayores asintomáticos

Univ. salud; 23 (3), 2021
Resumen Introducción: El momento articular durante la marcha se ha relacionado con diferentes procesos clínicos en la población adulto mayor, en Colombia no se cuentan con reportes propios. Objetivo: Analizar el momento aductor de la cadera durante la marcha de adultos mayores asintomáticos. Mat...

Biochemical characterization of the recombinant schistosome tegumental protein SmALDH_312 produced in E. coli and baculovirus expression vector system

BACKGROUND The heterologous expression of parasitic proteins is challenging because the sequence composition often differs significantly from host preferences. However, the production of such proteins is important because they are potential drug targets and can be screened for interactions with new lead ...

Scientific training of sports medicine for balance of knee joint muscle strength of athletes

Rev. bras. med. esporte; 27 (5), 2021
ABSTRACT Introduction: As skiers need to complete their movements in high mountains and snow, the athlete's landing's stability is directly related to the movement's success. The stable landing action wins high scores for the athletes' participating actions and protects their safety. Objective: This ar...

Production, characterization and kinetic model of biosurfactant produced by lactic acid bacteria

BACKGROUND Biosurfactants are surface active molecules produced by microorganisms which have the ability to disrupt the plasma membrane. Biosurfactant properties are important in the food, pharmaceu tical and oil industries. Lactic acid bacteria can produce cell-bound and excreted biosurfactants. RESULTS...

Potential application of a knowledgebase of iron metabolism of Acidithiobacillus ferrooxidans as an alternative platform

BACKGROUND: Acidithiobacillus ferrooxidans is a facultative anaerobe that depends on ferrous ion oxidation as well as reduced sulfur oxidation to obtain energy and is widely applied in metallurgy, environmental protection, and soil remediation. With the accumulation of experimental data, metabolic mechan...

LXYL-P1-2 immobilized on magnetic nanoparticles and its potential application in paclitaxel production

BACKGROUND: LXYL-P1-2 is the first reported glycoside hydrolase that can catalyze the transformation of 7-b-xylosyl-10-deacetyltaxol (XDT) to 10-deacetyltaxol (DT) by removing the D-xylosyl group at the C7 position. Successful synthesis of paclitaxel by one-pot method combining the LXYL-P1-2 and 10- deac...

Isokinetic strength, bilateral and unilateral strength differences: variation by age and laterality in elite youth football players

Int. j. morphol; 39 (1), 2021
SUMMARY: The purpose of this study was to investigate the effect of age on peak torque (PT) relative strength measures of knee extensors (KE) and knee flexors (KF), bilateral strength ratio (Q:Q, H:H), and ipsilateral strength ratio (H:Q) in youth elite male football players.Elite male players (n = 70) f...

Block slope is the main determinant of block phase performance in swimming

Rev. bras. med. esporte; 27 (1), 2021
ABSTRACT Introduction Swimming starts are an important component for decreasing the total race time, especially in short events. In this phase of swimming, the aim is to increase performance using many different techniques and starting platforms. Objectives The effects of height and slope of the star...

Identification and characterization of a novel 2R, 3R-Butanediol dehydrogenase from Bacillus sp. DL01

Electron J Biotechnol; 49 (), 2021
BACKGROUND: 2R,3R-butanediol dehydrogenase (R-BDH) and other BDHs contribute to metabolism of 3R/3S-Acetoin (3R/3S-AC) and 2,3-butanediol (2,3-BD), which are important bulk chemicals used in different industries. R-BDH is responsible for oxidizing the hydroxyl group at their (R) configuration. Bacillus s...