Results: 14

Development of enteric coated sustained release minitablets containing mesalamine

Braz. j. pharm. sci; 49 (3), 2013
The aim of this study was to develop and evaluate a multiparticulate modified release system, composed of minitablets with a sustained release matrix system coated with a pH-dependent release polymer, using mesalamine as a model drug. Polyox® WSR 1105 was the polymer used in the matrix system and Eudrag...

Development and evaluation of a hot-melt coating technique for enteric coating

Braz. j. pharm. sci; 48 (1), 2012
Conventional enteric coating requires the use of organic based polymers which are equally hazardous to the environment and operating personnel. Hot-melt coating avoids the use of solvents and is a safer and time-saving process. The present study was designed to assess the efficacy of hot-melt coating (HM...

Development and validation of dissolution method for carvedilol compression-coated tablets

Braz. j. pharm. sci; 47 (4), 2011
The present study describes the development and validation of a dissolution method for carvedilol compression-coated tablets. Dissolution test was performed using a TDT-06T dissolution apparatus. Based on the physiological conditions of the body, 0.1N hydrochloric acid was used as dissolution medium and ...

Recubrimiento pelicular con una dispersión de resinas acrílicas

El presente trabajo se realizó con el propósito de comprobar la conveniencia de la aplicación de resinas acrílicas en medio acuoso para recubrir tabletas, empleándose 2 tipos de tabletas, oblangos y ovaladas a los que se aplicaron 2 tipos de resinas acrílicas, una para cubierta entérica y otra par...