Gregorio, Cristian De;
Catalán, Evelyng;
Garrido, Gabriel;
Morandé, Pilar;
Castillo Bennett, Jimena;
Muñoz, Catalina;
Cofré, Glenda;
Huang, Ya-Lin;
Cuadra, Bárbara;
Murgas, Paola;
Calvo, Margarita;
Altermatt, Fernando;
Joao Yubero, María;
Palisson, Francis;
South, Andrew P;
Ezquer, Marcelo;
Fuentes, Ignacia.
BACKGROUND: Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a rare inherited skin disease caused by variants in the COL7A1 gene, coding for type VII collagen (C7), an important component of anchoring fibrils in the basement membrane of the epidermis. RDEB patients suffer from skin fragility starting...
RESUMEN Los organoides son estructuras miniaturizadas, generadas principalmente a partir de células madre pluripotentes inducidas, que se cultivan en el laboratorio conservando sus características innatas o adquiridas. Tienen el potencial de reproducir procesos de desarrollo biológico, modelar proceso...
Koh, Benson;
Rahman, Farynna Hana Ab;
Matlan, Najwa Amira;
Rajan, Manissha;
Mustaain, Aimi Yasmin;
Lee, Mohamad Ridhwan Mohd Jeffry;
Ramli, Roszalina;
Yunus, Siti Salmiah Mohd;
Idrus, Ruszymah Binti Hj;
Yazid, Muhammad Dain.
BACKGROUND: Functional bioengineered tooth regeneration using autologous or allogeneic alternative differentiated cells sources are thought to have a great potential in replacing conventional dentures. This study investigated the potential of dental pulp stem cells (DPSCs) conditioned medium for odontobl...
Skeletal muscle appears to play a central role in the development of insulin resistance (IR) and consequently the metabolic syndrome due to high-fat diets, obesity, and aging. Recent evidence suggests that some bioactive compounds present in natural products can affect blood glucose, possibly due to inte...
Miranda, Carla Maria Figueiredo de Carvalho;
Leonel, Luciano César Pereira Campos;
Koga, Bruna Andrade Aguiar;
Anunciação, Adriana Raquel de Almeida da;
Mario, Lara Carolina;
Favaron, Phelipe Oliveira;
Martins, Daniele dos Santos;
Vásquez, Bélgica;
Conei, Daniel;
Miglino, Maria Angélica;
Sol, Mariano del.
SUMMARY: The rabbit is considered an ideal animal model for studies that describe abnormalities in the testicles due to the similar morphogenetic mechanisms of sexual development and diseases commonly found in humans. The aim of this study was to determine the male sexual differentiation of the New Zeala...
Introducción. El grado de diferenciación celular en el estudio histopatológico del adenocarcinoma gástrico está descrito como un factor pronóstico determinante en el comportamiento clínico del tumor. El adenocarcinoma gástrico indiferenciado es considerado una variante agresiva de m...
ABSTRACT Myoblasts fuse into multinucleated muscle fibers to form and promote the growth of skeletal muscle. In order to analyze the role of myostatin (MSTN) in body fat, skeletal muscle cell proliferation and differentiation and energy metabolism, this study will use the antisense RNA technology of gene...
SUMMARY: Cellular differentiation is a highly regulated process that has vast implications for the mechanics of the cell. The interplay between differentiation induced cytoskeletal mechanical changes and strain on the nucleus is a potential cause of gene level changes. This study explores mechanical chan...
BACKGROUND: Lycium barbarum (also called wolfberry), a famous Chinese traditional medicine and food ingredient, is well recognized for its significant role in preventing obesity; however, the molecular mechanisms underlying its preventive effects on fat accumulation are not well understood yet. The aim o...
ABSTRACT Objective: To compare Transforming growth factor-β1 (TGF-β1) expression in various L-PRF concentrations on the hDPSC differentiation process. Material and Methods: hDPSC cell cultures were subjected to serum starvation by reducing FBS levels in the hDPSC culture media. Lysate PRF was...
