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L-arginine, a nitric oxide precursor, reduces dapsone-induced methemoglobinemia in rats

Moraes, Natália Valadares de; Bergamaschi, Mateus Machado; Bianchi, Maria de Lourdes Pires; Bragheto, Juliana Bordinassi; Malfará, Wilson Roberto; Queiroz, Regina Helena Costa.
Braz. j. pharm. sci; 48 (1), 2012
Dapsone use is frequently associated to hematological side effects such as methemoglobinemia and hemolytic anemia, which are related to N-hydroxylation mediated by the P450 enzyme system. The aim of the present study was to evaluate the influence of L-arginine supplementation, a precursor for the synthes...
Arginina/análisis, Metahemoglobinemia/clasificación, Dapsona/efectos adversos, Óxido Nítrico/farmacología, Dosis Única/clasificación
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Terapia hormonal de liberación transdérmica para el tratamiento de mujeres menopáusicas
Transdermal release hormone therapy for the treatment of menopausal women

Shulman, Lee.
Salud(i)ciencia (Impresa); 13 (2), 2005
The recent publication of the initial outcomes from the Women’s Health Initiative (WHI) study of menopausal management have cast concern on the safety of oral hormone therapy, despite the lack of new or increased risks associated with the use of hormone therapy. As with any study there are biases that ...
Terapia de Reemplazo de Estrógeno, Menopausia, Acetato de Medroxiprogesterona, Dosis Única, Estrógenos, Estrógenos Conjugados (USP), Hormonas, Mujeres, Resultado del Tratamiento, Terapéutica
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