Results: 28

Multiple sclerosis has a distinct lipid signature in plasma and cerebrospinal fluid

Arq. neuropsiquiatr; 77 (10), 2019
ABSTRACT The diagnosis of multiple sclerosis (MS) has changed over the last decade, but remains a composite of clinical assessment and magnetic resonance imaging to prove dissemination of lesions in time and space. The intrathecal synthesis of immunoglobulin may be a nonspecific marker and there are no p...

Neuromielitis óptica
Neuromyelitis optica

Medicina (B.Aires); 79 (supl.3), 2019
La neuromielitis óptica (NMO) es un trastorno autoinmune, inflamatorio y desmielinizante del sistema nervioso central con predilección por los nervios ópticos y médula espinal. En el año 2004 se publicó la asociación de NMO con un anticuerpo contra el canal de agua acuaporina 4 (anti-AQP4), como u...

Neurofilament light chain in the assessment of patients with multiple sclerosis

Arq. neuropsiquiatr; 77 (6), 2019
ABSTRACT Multiple sclerosis (MS) is an autoimmune, inflammatory, and degenerative disease of the central nervous system. Axonal degeneration is triggered by inflammation and is the pathological substrate of progressive disability in patients with MS. Therapeutic interventions can reduce inflammatory acti...

Doença de Addison e esclerose múltipla: relato de caso

A doença de Addison é uma endocrinopatia rara, de etiologia autoimune. É caracterizada por défice na secreção de glicocorticoides e mineralocorticoides. A esclerose múltipla consiste em patologia neurológica, de origem autoimune, que resulta na desmielinização da bainha de mielina. O objetivo d...

Lower urinary tract symptoms and sexual dysfunction in men with multiple sclerosis

Clinics; 74 (), 2019
OBJECTIVES: To assess the prevalence and interrelationship between lower urinary tract symptoms and sexual dysfunction in men with multiple sclerosis (MS). METHODS: In a cross-sectional study, we evaluated 41 men (mean age 41.1±9.9 years) with MS from February 2011 to March 2013, who were invited to pa...

Basal cortisol levels and the relationship with clinical symptoms in multiple sclerosis: a systematic review

Arq. neuropsiquiatr; 76 (9), 2018
ABSTRACT Multiple sclerosis (MS) is a demyelinating, progressive and neurodegenerative disease. A disturbance on the hypothalamic-pituitary-adrenal axis can be observed in patients with MS, showing altered cortisol levels. We aimed to identify basal cortisol levels and verify the relationship with clinic...

Enfermedades desmielinizantes
Demyelinating disorders

Medicina (B.Aires); 78 (supl.2), 2018
Las enfermedades desmielinizantes constituyen un grupo de afecciones de etiología autoinmune dirigida contra la mielina del sistema nervioso central. En muchos casos, el inicio del cuadro es precedido por una infección viral inespecífica. La esclerosis múltiple evoluciona con recaídas y remisiones c...

Protocolo clínico e diretrizes terapêuticas: esclerose múltipla

Psychiatric event in multiple sclerosis: could it be the tip of the iceberg?

Rev. bras. psiquiatr; 39 (4), 2017
Multiple sclerosis (MS) is a chronic progressive inflammatory disease of the central nervous system. Psychiatric comorbidities are highly prevalent in patients with MS, and can have drastic impact on quality of life and interpersonal relationships. Despite this high prevalence, whether psychiatric manife...

Characterization of the first symptoms of multiple sclerosis in a Brazilian center: cross-sectional study

Säo Paulo med. j; 135 (3), 2017
ABSTRACT CONTEXT AND OBJECTIVE: Multiple sclerosis (MS) is a chronic, immune-mediated and degenerative central nervous system (CNS) disease with well-established diagnostic criteria. Treatment can modify the course of the disease. The objective of this study was to describe the initial symptoms of mult...