Results: 18

Characterization of the first symptoms of multiple sclerosis in a Brazilian center: cross-sectional study

Säo Paulo med. j; 135 (3), 2017
ABSTRACT CONTEXT AND OBJECTIVE: Multiple sclerosis (MS) is a chronic, immune-mediated and degenerative central nervous system (CNS) disease with well-established diagnostic criteria. Treatment can modify the course of the disease. The objective of this study was to describe the initial symptoms of mult...

Malignant multiple sclerosis: clinical and demographic prognostic factors

Arq. neuropsiquiatr; 75 (3), 2017
ABSTRACT Patients with malignant multiple sclerosis (MMS) reach a significant level of disability within a short period of time (Expanded Disability Status Scale score of 6 within five years). The clinical profile and progression of the disease were analyzed in a Brazilian cohort of 293 patients. Twenty-...

Disability and progression in Afro-descendant patients with multiple sclerosis

Arq. neuropsiquiatr; 74 (10), 2016
ABSTRACT Multiple sclerosis (MS) prevalence is higher in Caucasian (CA) populations, narrowing the analysis of the impact of Afro-descendant (AD) populations in disease outcomes. Even so, recent studies observed that AD patients have a more severe course. The main objective of this study is to confirm an...

Olfactory alterations in patients with multiple sclerosis

Arq. neuropsiquiatr; 74 (9), 2016
ABSTRACT This cross-sectional study involves 100 multiple sclerosis (MS) and 100 non-MS patients, under the age of 60 years old, with nasal obstruction, traumatic brain injury, previous rhinoplasty or neurosurgery, and so forth. Objective To assess olfactory function using the Connecticut test and veri...

A disturbed processing of graviceptive pathways may be involved in the pathophysiology of balance disorders in patients with multiple sclerosis

Arq. neuropsiquiatr; 74 (2), 2016
ABSTRACT The purpose of this study was to determine the relationship between perception of verticality and balance disorders in multiple sclerosis patients. We evaluated patients and healthy controls. Patients were divided into two groups according to their risk of fall, with or without risk of fall, mea...

Qualidade de vida e desempenho ocupacional de indivíduos com esclerose múltipla

Acta fisiátrica; 22 (3), 2015
A esclerose múltipla (EM) é uma doença neurológica degenerativa e crônica com ampla gama de sinais e sintomas que podem comprometer a qualidade de vida (QV) e o desempenho ocupacional (DO) dos indivíduos que a exibem. Objetivo: Resumiu-se em avaliar a existência de possível correlação entre DO ...

Mecanismos patogénicos en el desarrollo de la esclerosis múltiple: ambiente, genes, sistema inmune y estrés oxidativo

Invest. clín; 56 (2), 2015
La esclerosis múltiple (EM) es la principal causa de discapacidad neurológica de origen no traumático en adultos jóvenes. EM es una enfermedad crónica inflamatoria que se caracteriza por daño a las fibras nerviosas y la cubierta de mielina. Esto produce una gran variedad de síntomas una vez que ne...