Abstract The present study was aimed to investigate the in vivo effects of Rosa canina extract on doxorubicin-induced testicular toxicity in mice for the first time. Male NMRI mice were randomly divided into six treatment groups (10=per group) as follows: (I) vehicles, (II) doxorubicin alone (3 mg/kg, i....
This study aimed to determine the mimosine level and examine the male reproductive toxicity effects of Leucaena leucocephala (LL) shoot tips plus young leaf extract. Mimosine level in LL extract was determined by thin layer chromatography before administration in animals. Male rats were divided into cont...
Methotrexate drug is commonly used to treat cancer; it is known to cause reproductive damage. Thymoquinone, as a natural component of herbs has many healthy benefits shown in researches. The present study aimed to investigate probable therapeutic effects of Thymoquinone against Methotrexate-induced damag...
Methotrexate (MTX) is commonly used as a chemotherapy agent and immune system suppressant but its adverse effect on male reproductive system is still limited. This study aimed to investigate the effect of MTX on structure and functional proteins of testis and seminal vesicle. Adult male rats were divided...
Although Momordica charantia (MC) has preventive effects on tissue injuries, antioxidant capacity and protective effect of MC pulp and peel (MCP) on valproic acid (VPA)-testicular damage have never been reported. Fresh MCPs were aqueous extracted and determined for antioxidant capacity and momordicine I ...
Momordica charantia,
Extractos Vegetales/administración & dosificación,
Antioxidantes/administración & dosificación,
Testículo/efectos de los fármacos,
Testículo/patología,
Ácido Valproico/toxicidad,
Esteroles/análisis,
Tamaño de los Órganos,
Testosterona/análisis,
Sustancias Protectoras,
Anticonvulsivantes/toxicidad,
Espermatozoides/efectos de los fármacos,
Fenoles/análisis,
Extractos Vegetales/química,
Cromatografía Líquida de Alta Presión,
Western Blotting,
Ratas Wistar
The environment is negatively affected by the increasing accumulation of both natural and man-made waste and by-products. Organophosphorous pesticides -malathion, diazinon and methamidophos- are used worldwide in pest control. The aim of this report is to review the effects of organophosphates on the mal...
Abstract Purpose: To determine the effect of folic acid (FA) on experimental testicular ischemia/reperfusion (I/R) in rats. Methods: Sixty male Wistar rats were randomly divided into 6 groups. The control group received physiologic saline orally. The sham-operated group received physiologic saline oral...
The aim of present study was to investigate the effect of Momordica cochinchinensis (Gag) aril (GA) aqueous extract on male reproductive system of streptozotocin (STZ)-induced hyperglycemia (HG) mice. GA were extracted with distilled water (DW) and analyzed for in vitro antioxidant capacities. ICR male m...
Momordica/química,
Extractos Vegetales/administración & dosificación,
Enfermedades Testiculares/tratamiento farmacológico,
Hiperglucemia/tratamiento farmacológico,
Diabetes Mellitus Experimental,
Testículo/efectos de los fármacos,
Fosforilación/efectos de los fármacos,
Tirosina,
Espermatozoides/efectos de los fármacos,
Antioxidantes/administración & dosificación,
Hipoglucemiantes/administración & dosificación,
Western Blotting,
Ratones Endogámicos ICR,
Recuento de Espermatozoides,
Antioxidantes/química,
Fenoles/análisis,
Flavonoides/análisis
Our aim was to describe sperm parameters in residents from Northern Chile. We evaluated in 101 volunteers (18 and 30 years old) urinary and drinking water Boron levels using Inductively Coupled Plasma Mass Spectrometry; semen parameters were measured with standardized methods. Each individual was categor...
Contaminantes Químicos del Agua/orina,
Boro/orina,
Chile,
Exposición a Compuestos Químicos,
Boro/toxicidad,
Contaminantes Químicos del Agua/toxicidad,
Espermatozoides/efectos de los fármacos,
Semen/química,
Semen/efectos de los fármacos,
Fertilidad/efectos de los fármacos,
Espectrometría de Masas/métodos,
Espermatozoides/patología
Abstract Objective To investigate the deleterious effects of air pollutants exposure in the Sao Paulo metropolitan region on semen quality in systemic lupus erythematosus (SLE). Methods A seven-years longitudinal repeated-measures panel study was performed at the Laboratory of Experimental Air Pollutio...
