LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Thyroxine increases Serca2 and Ryr2 gene expression in heart failure rats with euthyroid sick syndrome

Campanha, Fábio V G; Perone, Denise; Campos, Dijon H S de; Luvizotto, Renata de A M; De Síbio, Maria T; Oliveira, Miriane de; Olimpio, Regiane M C; Moretto, Fernanda C F; Padovani, Carlos R; Mazeto, Gláucia M F S; Cicogna, Antonio C; Nogueira, Célia R.

Arch. endocrinol. metab. (Online); 60 (6), 2016

ABSTRACT Objective The current study was aimed at analyzing sarcoplasmic reticulum Ca2+ ATPase (Serca2) and ryanodine receptor type 2 (Ryr2) gene expression in rats subjected to surgery that induced HF and were subsequently treated with T4 using physiological doses. Materials and methods HF was induc...

Estenosis de la Válvula Aórtica/complicaciones, Síndromes del Eutiroideo Enfermo/complicaciones, Síndromes del Eutiroideo Enfermo/tratamiento farmacológico, Síndromes del Eutiroideo Enfermo/genética, Expresión Génica/efectos de los fármacos, Insuficiencia Cardíaca/complicaciones, Modelos Animales, ARN Mensajero/metabolismo, Ratas Wistar, Canal Liberador de Calcio Receptor de Rianodina/efectos de los fármacos, Canal Liberador de Calcio Receptor de Rianodina/genética, ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/efectos de los fármacos, ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/genética, Tiroxina/administración & dosificación, Tiroxina/uso terapéutico, Triyodotironina/efectos de los fármacos

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Continuous spinal anaesthesia with minimally invasive haemodynamic monitoring for surgical hip repair in two patients with severe aortic stenosis

BACKGROUND AND OBJECTIVES: Aortic stenosis increases perioperative morbidity and mortality, perioperative invasive monitoring is advised for patients with an aortic valve area <1.0 cm2 or a mean aortic valve gradient >30 mm Hg and it is important to avoid hypotension and arrhythmias. We report the ...