Results: 17

Hepatic protective effect of grape seed proanthocyanidin extract against Gleevec-induced apoptosis, liver Injury and Ki67 alterations in rats

ABSTRACT Gleevec (imatinib) is an antineoplastic chemotherapeutic agent used in the treatment of many types of cancer. The current study was conducted to examine the possible modifying effects of grape seeds proanthocyandins extract (GSPE) against apoptosis, liver injury and Ki67 alterations induced by G...

Mechanical properties, water sorption characteristics, and compound release of grape seed extract-incorporated resins

J. appl. oral sci; 25 (4), 2017
Abstract Objective This study evaluated the effect of grape seed extract (GSE) incorporation on the mechanical properties, water sorption, solubility, and GSE release from the experimental adhesive resins. Material and Methods An experimental comonomer mixture, consisting of 40% Bis-GMA, 30% Bis MP, ...

Effects of grape seed extract on periodontal disease: an experimental study in rats

J. appl. oral sci; 25 (2), 2017
Abstract Natural compounds capable of modulating the host response have received considerable attention, and herbal products are suggested as adjunctive agents in periodontal disease treatment. Objective This study aimed to demonstrate the effect of grape seed extract (GSE) on periodontitis. Material ...

Atividade antimicrobiana do extrato de semente de uva Vitis vinifera sobre biofilme de Enterococcus faecalis: análise com microscopia confocal

As limitações dos irrigantes químicos utilizados em endodontia têm incentivado novas pesquisas acerca de substâncias alternativas para serem utilizadas no tratamento endodôntico. Estudos anteriores sugerem que o extrato de semente de uva (Vitis vinifera), tem atividade antimicrobiana assim como é ...

The effect of red grape seed extract on serum paraoxonase activity in patients with mild to moderate hyperlipidemia

Säo Paulo med. j; 134 (3), 2016
ABSTRACT: CONTEXT AND OBJECTIVE: Red grape seed extract (RGSE) contains oligomeric proanthocyanidin complexes as a class of flavonoids. These compounds are potent antioxidants and exert many health-promoting effects. This study aimed to determine the effects of RGSE on serum levels of triglycerides (TG...

Grape seed protects cholestatic rats liver from ischemia/reperfusion injury

Acta cir. bras; 31 (3), 2016
ABSTRACT PURPOSE: To determine the effect of grape-seed extract against ischemia/reperfusion injury in cholestatic liver. METHODS: Eighteen Wistar albino rats were divided into three groups. In control and study groups, cholestasis was provided by bile duct ligation. Seven days later, the rats were su...

Avaliação da composição química de óleos brasileiros de semente de uva (Vitis vinífera L) e seu efeito sobre parâmetros bioquímicos e inflamatórios em ratos

O óleo de semente de uva (OSU) caracteriza-se como um importante subproduto do processamento agroindustrial (vinicultura) que vem recebendo destaque como fonte alternativa de óleos vegetais. Os componentes químicos presentes nos óleos vegetais sofrem influência de fatores relacionados ao cultivo e a...