Results: 18

Granulocyte colony-stimulating factor combined with Methylprednisolone improves functional outcomes in rats with experimental acute spinal cord injury

Clinics; 73 (), 2018
OBJECTIVES: To evaluate the effects of combined treatment with granulocyte colony-stimulating factor (G-CSF) and methylprednisolone in rats subjected to experimental spinal cord injury. METHODS: Forty Wistar rats received a moderate spinal cord injury and were divided into four groups: control (no treat...

The safety and clinical efficacy of recombinant human granulocyte colony stimulating factor injection for colon cancer patients undergoing chemotherapy

Summary Objective: The present study was designed to evaluate safety and efficacy of recombinant human granulocyte colony stimulating factor (G-CSF) injection and whether this regimen could reduce the incidence of adverse events caused by chemotherapy. Method: A total of 100 patients with colon cancer ...

Revisão sistemática e análise de custo- minimização de lipegfilgrastim na profilaxia da neutropenia e da neutropenia febril relacionadas à quimioterapia citotóxica

Objetivo: Realizar avaliação econômica de lipegfilgrastim, fator de crescimento de longa duração (G-CSF), com os demais medicamentos da classe terapêutica disponíveis para a diminuição da duração da neutropenia grave (NG) e da incidência de neutropenia febril (NF), em pacientes adultos tratad...

Mobilization of hematopoietic progenitor cells for autologous transportation: consensus recommendations

SUMMARY Selected patients with certain hematological malignancies and solid tumors have the potential to achieve long-term survival with autologous hematopoietic progenitor cell transplant. The collection of these cells in peripheral blood avoids multiple bone marrow aspirations, results in faster engraf...

Ação educativa do enfermeiro no cuidado domiciliar de adolescentes e crianças: uso do fator estimulador de crescimento de colônia granulocítica (G-CSF) – uma perspectiva fenomenológica

Problema: Atualmente o câncer infantil representa a segunda causa de morte na faixa etária de 5 a 19 anos, ultrapassado apenas pelos óbitos provocados por causas externas. E, a partir do diagnóstico, traça-se uma das propostas de tratamento, a terapêutica com os agentes antineoplásicos, conhecidos...

O fator estimulador de colônias granulocitárias (G-CSF) para isquemia cerebral: uma nova aplicação terapêutica?: [carta ao editor]
Granulocyte colony-stimulating factor (G-CSF) for ischemic stroke: a new therapeutic modality?: [letter to the editor]

G-CSF is a FDA-approved drug, commonly utilized in neutropenic patients, long knows for its anti-inflammatory and angiogenic properties and also for its capacity to mobilize stem cells, hematopoiethic and endogen precursors and progenitor cells. Recently neuroprotective effects have been shown in animals...

Uso clínico de los factores de crecimiento hematopoyéticos

Iatreia; 7 (4), 1994
Los factores de crecimiento hematopoyético {FCH) son producto de la excitante y prometedora industria de la biología molecular y la Ingeniería genética. Se hace una revisión de la farmacología del Factor Estimulador de Colonias de Granulocitos y del Factor Estimulador de Colonias de Granulocitos-Ma...