Results: 23

Most common histopathological patterns of the Minas Gerais Association of the Centers of Nephrology

SUMMARY INTRODUCTION: We analyzed the distribution and frequency of glomerular diseases in patients biopsied between 1992 and 2016 in centers that make up the AMICEN (Minas Gerais Association of Nephrology Centers). METHODS: We analyzed the biopsy reports of patients from 9 AMICEN nephrology centers. W...

Hypoxia-induced hyperpermeability of rat glomerular endothelial cells involves HIF-2α mediated changes in the expression of occludin and ZO-1

Braz. j. med. biol. res; 51 (7), 2018
This study aimed to investigate the role of hypoxia-inducible factor-2α (HIF-2α) in the expression of tight junction proteins and permeability alterations in rat glomerular endothelial cells (rGENCs) under hypoxia conditions. The expression level of HIF-2α and tight junction proteins (occl...

Protective effect of resveratrol against morphine damage to kidneys of mice

Int. j. morphol; 35 (4), 2017
SUMMARY: Morphine produces free radicals and cause apoptosis in some cell. Resveratrol (RSV) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury. 48 male mice were randomly assigned to 8 groups. In this study, various doses of RSV (2, 8 and 20 mg/...

Current distribution pattern of biopsy-proven glomerular disease in Salvador, Brazil, 40 years after an initial assessment

J. bras. nefrol; 39 (4), 2017
Abstract Introduction: A report on the prevalence of glomerular disease diagnosed via renal biopsy in Salvador, BA, Brazil was published in 1973 and showed a predominance of membranoproliferative glomerulonephritis, which was frequently associated with hepatosplenic schistosomiasis. Objective: In this ...

Mujer joven, hija de padre con síndrome de Alport, debuta con síndrome nefrótico impuro

Rev. méd. Chile; 145 (5), 2017

The relationship between renal warm ischemia time and glomerular loss. An experimental study in a pig model

Acta cir. bras; 32 (5), 2017
Abstract Purpose: To investigate the glomerular number after different warm ischemia times. Methods: Thirty two pigs were assigned into four groups. Three groups (G10, G20, and G30) were treated with 10, 20, and 30 minutes of left renal warm ischemia. The sham group underwent the same surgery without r...

Glomerular loss after arteriovenous and arterial clamping for renal warm ischemia in a swine model

Acta cir. bras; 31 (11), 2016
ABSTRACT PURPOSE: To evaluate the glomerular loss after arteriovenous or arterial warm ischemia in a swine model. METHODS: Twenty four pigs were divided into Group Sham (submitted to all surgical steps except the renal ischemia), Group AV (submitted to 30 minutes of warm ischemia by arteriovenous clamp...

Quantitative analysis of the renal aging in rats. Stereological study

Acta cir. bras; 31 (5), 2016
ABSTRACT PURPOSE: To evaluate the renal function and the renal histological alterations through the stereology and morphometrics in rats submitted to the natural process of aging. METHODS: Seventy two Wistar rats, divided in six groups. Each group was sacrificed in a different age: 3, 6, 9, 12, 18 and...

Patogênese e tratamento da glomerulonefrite - uma atualização

J. bras. nefrol; 38 (1), 2016
Resumo A presente revisão traz os conceitos mais atuais acerca dos fatores de risco genéticos, eventos etiológicos, respostas nefritogênicas e tratamento dos principais tipos de glomerulonefrite (GN) imunomediada. Tais patologias incluem GN pós-infecciosa, nefropatia por IgA, doença por anticorpo a...