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Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children

Zhang, Zuojuan; Wang, Juandong; Ji, Buqiang; Bahr Greenwood, Tatiana von; Zhang, Yuan; Wang, Yongjing; Kong, Dexiao; Li, Ai; Jiang, Yang; Guo, Yanan; Liu, Xiaoli; Wang, Yingxue; Dou, Aixia; Li, Nailin; Henter, Jan-Inge; Sun, Guizhen; Zheng, Chengyun.
Clinics; 71 (4), 2016
OBJECTIVE: Hemophagocytic lymphohistiocytosis in adults is largely underdiagnosed. To improve the rate and accuracy of diagnosis in adults, the clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis were analyzed in and compared between adults and children in a Chinese cohort. MET...
Factores de Edad, China/epidemiología, Quimioterapia Combinada, Infecciones por Virus de Epstein-Barr/complicaciones, Infecciones por Virus de Epstein-Barr/diagnóstico, Hepatomegalia/epidemiología, Linfohistiocitosis Hemofagocítica/diagnóstico, Linfohistiocitosis Hemofagocítica/tratamiento farmacológico, Linfohistiocitosis Hemofagocítica/etiología, Esplenomegalia/epidemiología
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Atypical manifestations of Epstein-Barr virus in children: a diagnostic challenge

Bolis, Vasileios; Karadedos, Christos; Chiotis, Ioannis; Chaliasos, Nikolaos; Tsabouri, Sophia.
J. pediatr. (Rio J.); 92 (2), 2016
Abstract Objective: Clarify the frequency and the pathophysiological mechanisms of the rare manifestations of Epstein–Barr virus infection. Sources: Original research studies published in English between 1985 and 2015 were selected through a computer-assisted literature search (PubMed and Scopus)...
Infecciones por Virus de Epstein-Barr/complicaciones, Herpesvirus Humano 4/inmunología, Mononucleosis Infecciosa/virología
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