Results: 68

Innate and Th1/Th17 adaptive immunity in acute and convalescent Brazilian borreliosis disease

Braz. j. infect. dis; 25 (2), 2021
ABSTRACT Introduction: Brazilian borreliosis (BB) disease is an infectious disease transmitted by ticks that mimics Lyme disease (LD) from the Northern Hemisphere. The BB clinical picture is characterized by a pathognomonic skin lesion (migratory erythema) and joint, neurological, cardiac and psychiatri...

NK cells at the crossroads in COVID-19: a question of timing

Cienc. tecnol. salud; 7 (3), 2020
The outbreak of the novel coronavirus SARS-CoV-2 and the attendant physiological symptoms associated with the COVID-19 disease have led to an explosion of interest studying different aspects of the immune response. As of yet, the particular roles of natural killer cells are not well understood in this di...

Apoptosis de neutrófilos en la infección asintomática por Virus de la Inmunodeficiencia Humana
Neutrophil apoptosis in asymptomatic Human Immunodeficiency Virus infection

En los últimos años se ha determinado que los neutrófilos son células altamente versátiles y sofisticadas, cuyas funciones van mucho más allá de la eliminación de los microorganismos. En la infección con el Virus de Inmunodeficiencia Humana (HIV), si bien el papel de los neutrófilos no está to...

Otro desafío de la naturaleza: el nuevo coronavirus virología y fisiopatología del SARS-COV-2

The recent outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) has been brought to global attention in the search of knowledge about the virus and its pathogenesis. The immune response is essential to control and eliminate the infection, however, maladjust...

Caracterização fenotípica e funcional de células do sistema imune inato na malária cerebral experimental

A malária cerebral (MC) é responsável por muitas mortes ocasionadas pela infecção por Plasmodium falciparum. Devido à dificuldade em estudar os mecanismos imunes envolvidos no desenvolvimento de MC em humanos, o uso de modelos murinos de malária cerebral experimental (MCE) tem sido amplamente empr...

Why is SARS-CoV-2 infection milder among children?

Clinics; 75 (), 2020

17β-Estradiol, a potential ally to alleviate SARS-CoV-2 infection

Clinics; 75 (), 2020
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible ...

Caracterização fenotípica e genotípica de cepas de Salmonella spp. e subtipagem molecular de plasmídeos carreando genes de beta-lactamases de espectro estendido e AmpC

Salmonella spp. são reconhecidas como um dos mais importantes patógenos que ocasionam doença entérica, sendo a terceira causa de morte entre as doenças transmitidas por alimentos (DTAs). A maior preocupação atual deve-se ao aumento da resistência aos beta-lactâmicos, e a produção de beta-lacta...

Leishmania infantum induces high phagocytic capacity and intracellular nitric oxide production by human proinflammatory monocyte

Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND The mechanism of resistance to SbIII in Leishmania is complex, multifactorial and involves not only biochemical mechanisms, but also other elements, such as the immune system of the host. OBJECTIVES In this study, putative changes in the immunological profile of human monocytes infected wit...