Results: 27

Effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain

Prensa méd. argent; 105 (8), 2019
Background: Pain is defined as "unpleasant sensory and sensory experience", associated with actual or potential tissue domage or described in terms of such damage. Objetive: To assess the effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain. Patients and method:...

Evaluation of the neurotoxic effects of intrathecal administration of (S)-(+)-Ketoprofen on rat spinal cords: randomized controlled experimental study

Rev. bras. anestesiol; 69 (4), 2019
Abstract Background and objectives Intrathecal administration of non-steroidal anti-inflammatory drugs is more efficacious for post-operative pain management. Cyclooxygenase inhibiting non-steroidal anti-inflammatory drugs like (S)-(+)-Ketoprofen, may be effective at lower intrathecal doses than parente...

Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain

Arq. neuropsiquiatr; 76 (11), 2018
ABSTRACT Neuropathic pain is a chronic pain condition caused by damage or dysfunction of the central or peripheral nervous system. Electroacupuncture (EA) has an antinociceptive effect on neuropathic pain, which is partially due to inhibiting astrocyte activation in the spinal cord. We found that an intr...

Síndrome de degeneración combinada de la médula espinal y radiculopatía en dos pacientes por quimioterapia intratecal con metrotrexato y citarabina: casos clínicos

Rev. méd. Chile; 146 (6), 2018
Intrathecal chemotherapy may be complicated with the development of myelopathies or toxic radiculopathies. This myeloradicular involvement, of toxic character, is unpredictable, since these patients have repeatedly received Intrathecal chemotherapy with the same drugs without apparent injury. The toxic e...

Therapeutic advances in 5q-linked spinal muscular atrophy

Arq. neuropsiquiatr; 76 (4), 2018
ABSTRACT Spinal muscular atrophy (SMA) is a severe and clinically-heterogeneous motor neuron disease caused, in most cases, by a homozygous mutation in the SMN1 gene. Regarding the age of onset and motor involvement, at least four distinct clinical phenotypes have been recognized. This clinical variabili...

Ventriculitis post-quirúrgica por Pseudomonas aeruginosa extensamente resistente tratada con colistina intratecal. Comunicación de un caso pediátrico y revisión de la literatura científica

Rev. chil. infectol; 35 (3), 2018
Resumen El uso de colistina por vía intratecal se ha consolidado como una opción terapéutica para el manejo de infecciones del sistema nervioso central causadas por bacilos gramnegativos multi-resistentes. La evidencia del éxito terapéutico y del perfil de seguridad es creciente, particularmente en ...

Effect of equipotent doses of bupivacaine and ropivacaine in high-fat diet fed neonatal rodent model

Rev. bras. anestesiol; 67 (2), 2017
Abstract Objectives: The increase in the prevalence of obesity presents a significant health and economic problem. Obesity has been reported to be a major contributor to variety of chronic diseases. Childhood obesity has been rising over the past decades leading to various complications in health. Milli...

Spinal injection of local anesthetic during cervical facet joint injection

Rev. bras. anestesiol; 66 (6), 2016
Abstract Introduction: Facet joint pain is a common source of non-radicular back pain worldwide. Non-surgical interventional modalities remain the mainstay in the treatment of facetogenic back pain and comprise the second most commonly performed interventional pain procedures in the USA. Case: A 36 yea...

Effect of S-methyl-l-thiocitrulline dihydrochloride on rat micturition reflex

Int. braz. j. urol; 42 (5), 2016
ABSTRACT Objective: To evaluate the effect of neuronal nitric oxide synthase on the striated urethral sphincter and the urinary bladder. Materials and Methods: A coaxial catheter was implanted in the proximal urethra and another one in the bladder of female rats, which were anesthetized with subcutaneo...

Neurotoxic effects of levobupivacaine and fentanyl on rat spinal cord

Rev. bras. anestesiol; 65 (1), 2015
BACKGROUND: The purpose of the study was to compare the neurotoxic effects of intrathecally administered levobupivacaine, fentanyl and their mixture on rat spinal cord. METHODS: In experiment, there were four groups with medication and a control group. Rats were injected 15 µL saline or fentanyl 0.0005 ...