LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Salivary anti-PGL-1 IgM may indicate active transmission of Mycobacterium leprae among young people under 16 years of age

Macedo, Alexandre Casimiro de; Cunha Jr, José Evandro; Yaochite, Juliana Navarro Ueda; Tavares, Clodis Maria; Nagao-Dias, Aparecida Tiemi.

Braz. j. infect. dis; 21 (5), 2017

Abstract Considering that the main route of Mycobacterium leprae transmission is the upper respiratory tract, detection of salivary antibodies can be a useful tool for diagnosing early infection. The study aimed to analyze salivary anti-PGL-1 IgA and IgM antibodies in 169 children aged 4-16 years old, wh...

Anticuerpos Antibacterianos/administración & dosificación, Antígenos Bacterianos/análisis, Antígenos Bacterianos/inmunología, Trazado de Contacto, Ensayo de Inmunoadsorción Enzimática, Familia, Glucolípidos/análisis, Glucolípidos/inmunología, Lepra Multibacilar/diagnóstico, Lepra Paucibacilar/diagnóstico, Mycobacterium leprae/inmunología, Saliva/química, Saliva/inmunología

Fulltext

Wade's histoid leprosy in a 14-year-old teenage boy

Figueira, Renata Borges Fortes da Costa; Oliveira, Karen Fernandes de; Souza, Luciana Borges de; Takano, Gustavo Henrique Soares; Motta, Jorgeth de Oliveira Carneiro da; Costa, Izelda Maria Carvalho.

Rev. Soc. Bras. Med. Trop; 50 (4), 2017

Abstract Wade's histoid leprosy (HL) is a rare variant of multibacillary leprosy, with characteristic clinical, immunologic, histopathologic, and bacteriologic features. It is associated with resistance to sulfa drugs or polychemotherapy and is rarely observed in patients who have not undergone prior tre...

Diagnóstico Diferencial, Lepra Multibacilar/diagnóstico, Lepra Multibacilar/patología, Piel/patología

Fulltext

Analysis of clinical data and T helper 1/T helper 2 responses in patients with different clinical forms of leprosy

Rodrigues, Ricardo Wilson de Pinho; Ribeiro, Afonso Bezerra; Berber, Gilcele de Campos Martin; Sheng, LeeYun; Damazo, Amilcar Sabino.

Rev. Soc. Bras. Med. Trop; 50 (2), 2017

Abstract INTRODUCTION: Currently, there are no laboratory tests or sensitive and specific molecular markers for the early diagnosis of leprosy. The aim of this study was to analyze the clinical characteristics of patients with leprosy and investigate their immunological profile, comparing this with the ...

Biopsia, Estudios Transversales, Técnica del Anticuerpo Fluorescente, Lepra Multibacilar/clasificación, Lepra Multibacilar/diagnóstico, Lepra Multibacilar/inmunología, Lepra Paucibacilar/clasificación, Lepra Paucibacilar/diagnóstico, Lepra Paucibacilar/inmunología, Persona de Mediana Edad, Células TH1/inmunología, Células TH1/metabolismo, Células Th2/inmunología

Fulltext

Type 2 leprosy reaction with Sweet's syndrome-like presentation

Chiaratti, Francielle Chiavelli; Daxbacher, Egon Luiz Rodrigues; Neumann, Antonielle Borges Faria; Jeunon, Thiago.

An. bras. dermatol; 91 (3), 2016

Abstract Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clini...

Lepra Multibacilar/diagnóstico, Síndrome de Sweet/diagnóstico, Eritema/diagnóstico, Histiocitos/patología, Leprostáticos/uso terapéutico, Lepra Multibacilar/complicaciones, Lepra Multibacilar/tratamiento farmacológico, Lepra Multibacilar/patología, Neutrófilos/patología, Prednisona/uso terapéutico, Síndrome de Sweet/tratamiento farmacológico, Síndrome de Sweet/etiología, Síndrome de Sweet/patología, Talidomida/uso terapéutico

Fulltext