Results: 28

Lichen planopilaris developed during childhood

An. bras. dermatol; 92 (4), 2017
Abstract: Lichen planopilaris is a disease that appears with lymphocytic cicatricial alopecia. It is considered a follicular variant of lichen planus. The examination of affected areas shows alopecia with perifollicular erythema and scaling, revealing a predilection for hair follicles. The involvement of...

Frontal fibrosing alopecia and extrafacial lichen planus pigmentosum in a caucasian woman

An. bras. dermatol; 92 (5,supl.1), 2017
Abstract We present the case of a 72-year-old Caucasian woman with frontal fibrosing alopecia of one year's duration. Eighteen months later, she presented with sudden hyperpigmentation on the submental area, neck and upper chest. Histopathological examination was consistent with lichen planus pigmentosus...

Frontal fibrosing alopecia and lichen planus pigmentosus: diagnosis and therapeutic challenge

An. bras. dermatol; 92 (5,supl.1), 2017
Abstract Frontal fibrosing alopecia is a variant of lichen planopilaris with marginal progressive hair loss on the scalp, eyebrows and axillae. We report a case of frontal fibrosing alopecia and lichen planus pigmentosus in a postmenopausal woman, that started with alopecia on the eyebrows and then on th...

"String of pearls pattern": report of three cases of non clear-cell acanthoma

An. bras. dermatol; 92 (5,supl.1), 2017
Abstract The coiled and dotted vessels in a serpiginous arrangement or "string of pearls" is considered a classical vascular pattern associated with clear cell acanthoma. We present three cases of epidermal tumors different from clear cell acanthoma that have the same "string of pearls" vascular pattern....

DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms

An. bras. dermatol; 91 (6), 2016
Abstract The transforming growth factor-beta 1 (TGFβ1) promotes fibrosis, differentiating epithelial cells and quiescent fibroblasts into myofibroblasts and increasing expression of extracellular matrix. Recent investigations have shown that PPAR (peroxisome proliferator-activated receptor*) is a ne...

Coexistence of nail lichen planus and lichen planus pigmentosus

An. bras. dermatol; 91 (5,supl.1), 2016
Abstract We describe a fifty-six-year old, Afro-descendent female patient showing dystrophy of her twenty nails and hyperchromic, asymptomatic macule on her face. Histopathological examination of the macule showed vacuolization of the basal layer, melanophages in the superficial dermis and lymphoplasmocy...

Frontal fibrosing alopecia in association with Sjögren's syndrome: more than a simple coincidence

An. bras. dermatol; 91 (5,supl.1), 2016
Abstract Frontal fibrosing alopecia is a distinctive form of scarring alopecia considered to be a clinical variant of lichen planopilaris. It predominantly occurs in postmenopausal women and has a slowly progressive course. It was first described by Kossard in 1994. Since then the number of reported case...

Lichen planopilaris-like eruption during treatment with tyrosine kinase inhibitor nilotinib

An. bras. dermatol; 91 (5,supl.1), 2016
Abstract Tyrosine kinase inhibitors are effective as a target therapy for malignant neoplasms. Imatinib was the first tyrosine kinase inhibitor used. After its introduction, several other drugs have appeared with a similar mechanism of action, but less prone to causing resistance. Even though these drugs...