Ali, M M;
Baig, M T;
Huma, A;
Ibrahim, S;
Khan, S A;
Fatima, R;
Majeed, S;
Rawat, A;
Soomro, H;
Lodhi, M;
Jabeen, A;
Syed, N;
Huda, A.
Abstract Increased anxiety and depressive symptoms have reported to be its association with long term illness. Because of having unwanted effects of newly available drugs, patients administering anxiolytic drugs usually discontinue the treatment before they are completely recovered. Therefore, there is a...
SUMMARY: The potential anti-inflammatory and antifibrotic activity of polyphenolic extracts of blueberry and grape was evaluated in a mouse model of lung damage induced by subcutaneous administration of bleomycin. The results of testing the polyphenolic extracts on two different systemic administration v...
Bleomicina/toxicidad,
Lesión Pulmonar/inducido químicamente,
Lesión Pulmonar/tratamiento farmacológico,
Lesión Pulmonar/patología,
Pulmón/efectos de los fármacos,
Polifenoles/administración & dosificación,
Extractos Vegetales/administración & dosificación,
Antiinflamatorios/administración & dosificación,
Modelos Animales de Enfermedad,
Arándanos Azules (Planta)/química,
Vitis/química
SUMMARY: The therapeutic effect of a granulocyte-colony stimulating factor (G-CSF) biosimilar drug, zarzio, on non-alcoholic fatty liver disease (NAFLD) in a rat model was investigated in this study. Thirty-two rats were randomly divided into four groups. Groups I and II were fed a standard laboratory di...
Factor Estimulante de Colonias de Granulocitos/administración & dosificación,
Biosimilares Farmacéuticos/administración & dosificación,
Enfermedad del Hígado Graso no Alcohólico/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Inmunohistoquímica,
Factor de Necrosis Tumoral alfa/efectos de los fármacos,
Células Secretoras de Insulina/efectos de los fármacos,
Factor 2 Relacionado con NF-E2,
d0009750,
Dieta Alta en Grasa/efectos adversos,
Caspasa 3
Antecedentes: La ECA2 ha mostrado ser un regulador esencial de la funcionalidad cardíaca. En un modelo experimental de insuficiencia cardíaca (IC) con Fier, modelo de coartación de aorta (COA), se encontró activación de la vía Rho-kinasa. La inhibición de esta vía con fasudil no mejoró el remode...
Cinnamon (
Cinnamomum verum
J.
Presl) is a well
-
known medicinal plant considered as an
effective treatment for neurological disorders based on Persian medicine
. The aim of the present study
was assessing the effect of cinnamon oil, cinnamic acid, and cinnamaldehyde,...
Cinnamomum zeylanicum/química,
Cromatografía Líquida de Alta Presión,
Enfermedades Neurodegenerativas/tratamiento farmacológico,
Enfermedad de Parkinson/tratamiento farmacológico,
Medicina Tradicional,
Aceites Volátiles/administración & dosificación,
Aceites Volátiles/química,
Cinamatos,
Acroleína/análogos & derivados,
1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina,
Modelos Animales de Enfermedad,
Especies Reactivas de Oxígeno,
Células PC12
SUMMARY: Mormodica balsamina is a valuable medicinal plant that is used to treat wounds and inflammation; its leaves are also used as an antibiotic and in the treatment of stomach pain. This study was conducted to determine the anti-ulcer activity of methanolic leaf extract of Mormodica balsamina on etha...
Momordica/química,
Momordica balsamica,
Extractos Vegetales/administración & dosificación,
Hojas de la Planta,
Etanol/toxicidad,
Úlcera Gástrica/tratamiento farmacológico,
Mucosa Gástrica/efectos de los fármacos,
Plantas Medicinales,
Úlcera Gástrica/inducido químicamente,
Extractos Vegetales/química,
Antiulcerosos/administración & dosificación,
Antiulcerosos/química,
Modelos Animales de Enfermedad
SUMMARY: This study investigated the role and mechanism of aspirin combined with rehabilitation training in the nerve injury repair and Schwann cell changes in rats with sciatic nerve injury. Totally, 120 male healthy SD rats were randomly divided into sham, model, aspirin, and aspirin + rehabilitation g...
SUMMARY: To investigate changes of MMP-9 in the rat spleen and hypoxia-induced microvascular basement membrane under high altitude hypoxia. Thirty male specific pathogen-free Sprague Dawley rats were randomly divided into control and hypoxia groups, with 15 rats in each group. The rats in the control gro...
SUMMARY: It is known that diabetes mellitus has late complications, including microvascular and macrovascular diseases. Diabetes can affect bones through biochemical markers of bone structure, density, and turnover. This study aimed to biomechanically investigate the bone-protective effects of angiotensi...
SUMMARY: The aim of this systematic review was to assess the histological effects of platelet-rich plasma (PRP) on temporomandibular joint osteoarthritis (TMJ-OA) in animal models. A systematic search was performed using PubMed, WoS, EMBASE, Science Direct and SCOPUS databases. The inclusion criteria wer...
