Background: Underwater endoscopic mucosal resection (UEMR) emerges as a less complex alternative to endos-
copic submucosal resection (ESD) for the treatment of colorectal lesions. We present two clinical cases of complex
colon adenomas resolved using UEMR technique. Case 1: A 56-years-old male patient w...
Introduction: Colorectal cancer is the third most common malignant neoplasm worldwide, with ~ 150 thousand new cases each year. Screening policies have brought significant progress due to the possibility of early diagnosis and polyp resection. Therefore, there is a need for continuous evaluation of the q...
Introduction: Almost 25% of colorectal cancer (CRC) patients have synchronous colorectal liver metastasis (SCLM) coinciding with the disease diagnosis. Liver-first approach for the treatment of SCLM involves neoadjuvant chemotherapy, subsequent liver resection, and then primary tumor resection. This stra...
Adenoma detection rate (ADR) is a key quality indicator in screening colonoscopy, closely linked to colorectal
cancer (CRC) prevention. Currently, the minimum recommended ADR is > 30% with an aspirational goal of >
35%; and the sessile serrated lesion detection rate (SSLDR) minimum is > 7% with an aspira...
O câncer colorretal (CCR) é a segunda maior causa de morte por câncer no mundo. Os efeitos colaterais das terapias convencionais, normalmente agressivos, são comuns em todos os tratamentos indicados aos cânceres. O objetivo deste estudo foi avaliar os efeitos de fitoquímicos extraídos da pele de a...
Introduction: Chemotherapy response in early age-onset colorectal cancer patients is still controversial, and the results of chemotherapy response are unknown. Therefore, the purpose of this study is to determine the relationship between the age of colorectal cancer patients and histopathological feature...
SUMMARY: To evaluate the anti-cancer effects of yeast extract on resistant cells, autophagy and necroptosis were investigated in 5-fluorouracil (5-FU)-resistant colorectal cancer cells. Further underlying characteristics on drug resistance were evaluated, focused on ERK-RSK-ABCG2 linkage. SNU-C5 and 5-FU...
Extractos Vegetales/farmacología,
Neoplasias Colorrectales/tratamiento farmacológico,
Resistencia a Antineoplásicos,
Fluorouracilo,
Autofagia,
Antineoplásicos/farmacología,
Proteínas Quinasas S6 Ribosómicas 90-kDa,
Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2,
Células Tumorales Cultivadas,
Levaduras,
Necroptosis,
Supervivencia Celular/efectos de los fármacos,
Western Blotting,
Electroforesis
Introducción: El cáncer colorrectal es la neoplasia más frecuente del sistema digestivo en los adultos mayores. En Cuba es un problema de salud de primer orden por su elevada incidencia y mortalidad, que constituye la tercera causa de muerte. Objetivo: Caracterizar a los adultos mayores con cáncer co...
Introducción: El melanoma anorrectal es un tumor infrecuente que se caracteriza por ser agresivo y de mal pronóstico; constituye el 1 por ciento entre los tumores malignos colorrectales. Es más frecuente en pacientes femeninas de más de 50 años y alcanza un pico máximo en la octava década de la vi...
Introducción. La neoplasia colorrectal es una patología oncológica muy frecuente a nivel mundial y una de las causas más comunes de mortalidad por cáncer. La epidemiologia, diagnóstico y tratamiento han sido ampliamente estudiadas, mientras que los datos sobre la enfermedad metastá...
