SUMMARY OBJECTIVE: Extracranial metastases of glioblastoma multiforme (GBM) are rare due to the short survival experienced by the patients. Therefore, the natural history of GBM metastases remains elusive. The identification of clinical factors promoting GBM metastases may help elucidate the mechanisms ...
Neoplasias Encefálicas/diagnóstico por imagen,
Neoplasias Encefálicas/mortalidad,
Neoplasias Encefálicas/patología,
Glioblastoma/diagnóstico por imagen,
Glioblastoma/mortalidad,
Glioblastoma/secundario,
Neoplasias Pulmonares/diagnóstico por imagen,
Neoplasias Pulmonares/mortalidad,
Neoplasias Pulmonares/secundario,
Imagen por Resonancia Magnética/métodos,
Estadísticas no Paramétricas,
Factores de Tiempo,
Tomografía Computarizada por Rayos X/métodos
SUMMARY Chordoid glioma (CG) is considered a slow growing glial neoplasm. We report two new cases with endocrinological presentation, management and outcome. Case reports: 1) An 18 year-old female patient was admitted due to headaches, nausea and vomiting and visual abnormalities. She was in amenorrhea. ...
Biopsia,
Neoplasias Encefálicas/diagnóstico por imagen,
Neoplasias Encefálicas/patología,
Neoplasias Encefálicas/cirugía,
Resultado Fatal,
Glioma/diagnóstico por imagen,
Glioma/patología,
Glioma/cirugía,
Imagen por Resonancia Magnética,
Silla Turca,
Tercer Ventrículo/diagnóstico por imagen,
Tercer Ventrículo/patología,
Tercer Ventrículo/cirugía,
Resultado del Tratamiento
SUMMARY OBJECTIVE: This study aims to compare estrogen receptor expression between low and high-grade astrocytomas. METHOD: A study using paraffin blocks of glial tumors from the Anatomy Pathology archives of São Marcos Hospital was carried out and began after approval by the Review Board of the Feder...
ABSTRACT CONTEXT: Central nervous system (CNS) infectious diseases have high prevalence in developing countries and their proper diagnosis and treatment are very important for public health planning. Cryptococcus neoformans is a fungus that may cause several CNS manifestations, especially in immunocompr...
Neoplasias Encefálicas/diagnóstico por imagen,
Neoplasias Encefálicas/patología,
Infecciones Fúngicas del Sistema Nervioso Central/diagnóstico por imagen,
Infecciones Fúngicas del Sistema Nervioso Central/patología,
Criptococosis/diagnóstico por imagen,
Criptococosis/patología,
Cryptococcus neoformans/aislamiento & purificación,
Diagnóstico Diferencial,
Resultado Fatal,
Inmunocompetencia,
Huésped Inmunocomprometido,
Imagen por Resonancia Magnética,
Enfermedades Raras/diagnóstico por imagen,
Enfermedades Raras/patología,
Tomografía Computarizada por Rayos X
SUMMARY OBJECTIVE To evaluate the survival of patients with brain metastases treated surgically according to the potentially involved factors. METHODS 71 patients treated surgically were analyzed with the diagnosis of brain metastases during the period from January 2011 to November 2014, totaling 47 ...
Distribución por Edad,
Factores de Edad,
Neoplasias Encefálicas/mortalidad,
Neoplasias Encefálicas/patología,
Neoplasias Encefálicas/secundario,
Neoplasias Encefálicas/terapia,
Estimación de Kaplan-Meier,
Estado de Ejecución de Karnofsky,
Neoplasias Renales/mortalidad,
Neoplasias Renales/patología,
Neoplasias Pulmonares/mortalidad,
Neoplasias Pulmonares/patología,
Persona de Mediana Edad,
Análisis Multivariante,
Metástasis de la Neoplasia,
Neoplasias Primarias Desconocidas/mortalidad,
Neoplasias Primarias Desconocidas/patología,
Neoplasias de la Próstata/mortalidad,
Neoplasias de la Próstata/patología,
Estudios Retrospectivos,
Factores de Riesgo,
Distribución por Sexo,
Factores Sexuales
Calastri, Maria Clara Jessica;
Rodrigues, Nicolas Luz Toledo Ortega;
Hatori, Gabriela;
Gregório, Michele Lima;
Brancati, Camila Ive Ferreira Oliveira;
Zanovelo, Eliane Milharcix;
Ferraz Filho, José Roberto Lopes;
Neiva, Cassiano Merussi;
Rodrigues Junior, Antonio Carlos Ponde;
Godoy, Moacir Fernandes de;
Lancelloti, Carmen Lucia Penteado;
Tognola, Waldir Antonio;
Souza, Dorotéia Rossi Silva.
ABSTRACT Background Glioma, the most common primary malignant brain tumor in adults, is highly aggressive and associated with a poor prognosis. The objectives of this study were to evaluate the association of genetic polymorphisms related to angiogenesis and apoptosis with gliomas, as well as comorbidi...
Antineoplásicos Alquilantes/administración & dosificación,
Apoptosis/genética,
Neoplasias Encefálicas/genética,
Neoplasias Encefálicas/patología,
Neoplasias Encefálicas/terapia,
Terapia Combinada,
Dacarbazina/administración & dosificación,
Dacarbazina/análogos & derivados,
Genotipo,
Glioma/genética,
Glioma/patología,
Glioma/terapia,
Estimación de Kaplan-Meier,
Estilo de Vida,
Neovascularización Patológica,
Polimorfismo Genético/genética,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Temozolomida
Pineal cavernous angioma is a vascular malformation that has a prevalence lower than
1%. The etiology is debated. It is believed that it is originated from an autosomal
dominant inheritance or from radiotherapeutic treatment. Complete resection enables
the cure and prevents complications of the natural e...
Papillary tumor of the pineal region (PTPR) is a neuroectodermal tumor thought to
originate from cells of the subcommissural organ. Its oncologic properties are still
under investigation, as well as the most suitable therapeutic measures for this type of
neoplasm.We report the case of a 36-year-old woman...
Diagnóstico Diferencial,
Neoplasias Encefálicas/cirugía,
Carcinoma Papilar/cirugía,
Glándula Pineal/cirugía,
Carcinoma Papilar/patología,
Derivación Ventriculoperitoneal,
Carcinoma Papilar/diagnóstico por imagen,
Inmunohistoquímica,
Neoplasias Encefálicas/diagnóstico por imagen,
Glándula Pineal/diagnóstico por imagen,
Neoplasias Encefálicas/patología,
Glándula Pineal/patología
Tirapelli, Daniela Pretti da Cunha;
Lustosa, Isis Lacrose;
Menezes, Sarah Bomfim;
Franco, Indira Maynart;
Rodrigues, Andressa Romualdo;
Peria, Fernanda Maris;
Marinho, Alexandre Magno da Nóbrega;
Serafini, Luciano Neder;
Carlotti Jr, Carlos Gilberto;
Tirapelli, Luís Fernando.
ABSTRACT Glioblastoma (GBM) is the most malignant glioma and represents 29% of all brain tumors. Tumorigenesis is intimately connected with characteristics acquired in the physiologic pathway of cellular death. Objective: In the present study, the expression of anti-apoptotic (XIAP and Bcl-2) and apopto...
Apoptosis,
Neoplasias Encefálicas/genética,
Neoplasias Encefálicas/metabolismo,
Neoplasias Encefálicas/patología,
Línea Celular Tumoral,
Regulación Neoplásica de la Expresión Génica,
Glioblastoma/genética,
Glioblastoma/metabolismo,
Glioblastoma/patología,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Proteína Inhibidora de la Apoptosis Ligada a X/genética,
Proteína Inhibidora de la Apoptosis Ligada a X/metabolismo,
Proteínas Proto-Oncogénicas c-bcl-2/metabolismo,
Proteínas Proto-Oncogénicas c-bcl-2/genética
Solution reflux and edema hamper the convection-enhanced delivery of the standard treatment for glioma. Therefore, a real-time magnetic resonance imaging (MRI) method was developed to monitor the dosing process, but a quantitative analysis of local diffusion and clearance parameters has not been assessed...
Western Blotting,
Neoplasias Encefálicas/diagnóstico por imagen,
Neoplasias Encefálicas/patología,
Difusión,
Progresión de la Enfermedad,
Espacio Extracelular/diagnóstico por imagen,
Gadolinio DTPA,
Glioma/diagnóstico por imagen,
Glioma/patología,
Inmunohistoquímica,
Imagen por Resonancia Magnética/métodos,
Ratas Sprague-Dawley
