LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud | LILACS

Results: 27

Integrated care pathway for rectal cancer treatment: cross-sectional post-implementation study using a logic model framework

Säo Paulo med. j; 137 (5), 2019
ABSTRACT BACKGROUND: Management of rectal cancer has become more complex with multimodality therapy (neoadjuvant chemoradiotherapy and surgery) and this has led to the need to organize multidisciplinary teams. The aim of this study was to report on the planning, implementation and evaluation of an inte...

Capítulo 4. Indicaciones y resultados oncológicos de la resección local transanal
Chapter 4. Indications and oncological results of transanal local resection

Oncological outcomes in extended time intervals between preoperative chemoradiotherapy with capecitabine and surgery in operable rectal adenocarcinoma

Objective: To assess whether extended time intervals (8-12, 13-20 and >20 weeks) between the end of neoadjuvant chemoradiotherapy and surgery affect overall survival, disease-free survival. Materials and methods: Retrospective study in 120 patients with rectal adenocarcinoma without evidence of metastasi...

Individualized threshold for tumor segmentation in 18F-FDG PET/CT imaging: The key for response evaluation of neoadjuvant chemoradiation therapy in patients with rectal cancer?

Summary Introduction: The standard treatment for locally advanced rectal cancer (RC) consists of neoadjuvant chemoradiation followed by radical surgery. Regardless the extensive use of SUVmax in 18F-FDG PET tumor uptake as representation of tumor glycolytic consumption, there is a trend to apply metabol...

La preservación del recto como alternativa en pacientes con cáncer localmente avanzado
Preserving the rectum as an alternative in patients with locally advanced cancer

Neoadjuvant therapy and surgery for rectal cancer. Comparative study between partial and complete pathological response

Arq. gastroenterol; 53 (3), 2016
ABSTRACT Background The approach of locally advanced extra-peritoneal rectal adenocarcinoma implies a treatment with neoadjuvant chemoradiotherapy associated with total mesorectal excision surgery. However, the tumors respond variably to this neoadjuvant therapy, and the mechanisms for response are not ...

The impact of laparoscopic surgery in colorectal cancer resection with respect to the development of liver metastasis in the long-term

INTRODUCTION: Colorectal cancer (CRC) shows high incidence and mortality worldwide, particularly in Western and developed countries. The objective of this study is to evaluate the oncologic results during a minimum follow-up of 2 years of curable CRC patients submitted to laparoscopic resection in our e...

Marcadores e mecanismos de resistência à terapia neoadjuvante e o papel das vesículas extracelulares secretadas pelas células tumorais no câncer de reto

O câncer de reto é o segundo tumor mais comum no intestino grosso correspondendo a um terço do total de casos de câncer colorretal (CCR). Pacientes com câncer de reto em estádios II e III são tratados com radioquimioterapia neoadjuvante seguida de ressecção cirúrgica do tumor. Análises das peÃ...

Analysis of neutrophil-lymphocyte ratio as a prognostic element in the response to neoadjuvant therapy in rectal cancer

INTRODUCTION: The previous radio-chemotherapy approach is highly relevant in the management of rectal cancer, collaborating on organ functional preservation, being performed prior to surgery. The inflammatory response plays an important role in this treatment. OBJECTIVE: It consists in correlating the nu...

Regressão do estádio clínico, preservação esfincteriana e qualidade de vida em câncer de reto: resultados de um estudo prospectivo randomizado comparando dois esquemas de radioquimioterapia neoadjuvante

Introdução: O tratamento do câncer de reto localmente avançado é a radioquimioterapia, seguido de ressecção, reduzindo a taxa de recidiva local. Estudos sugerem que a capecitabina, uma droga oral, usada como droga única combinada à radioterapia neoadjuvante em substituição ao 5-fluorouracil e ...