Results: 23

Human plasma fibronectin promotes proliferation and differentiation of odontoblast

J. appl. oral sci; 25 (3), 2017
Abstract Objective To assess the effect of fibronectin (Fn) and porcine type I collagen (PCOL) on odontoblast-like cells in vitro. Material and Methods Rat odontoblast-like cells (MDPC-23 cells) were inoculated and cultured on Fn-coated or type I collagen-coated substrates. Proliferation assay, alkal...

Biostimulatory effects of simvastatin on MDPC-23 odontoblast-like cells

Abstract: The aim of this study was to evaluate the bioactivity and cytocompatibility of simvastatin (SV) applied to MDPC-23 odontoblast-like cells. For this purpose, MDPC-23 cells were seeded in 96-well plates and submitted to treatments with 0.01 or 0.1 μM of SV for 24 h, 72 h or continuously thro...

Effect of CRABP2 on the proliferation and odontoblastic differentiation of hDPSCs

Abstract: Cellular retinoic acid-binding protein 2 (CRABP2) has been detected in several organs during embryonic development. Recent studies have demonstrated that CRABP2 plays important roles in the retinoic acid, β-catenin and Notch signaling pathways, as well as in the interaction between epithel...

Evaluation of an experimental rat model for comparative studies of bleaching agents

J. appl. oral sci; 24 (2), 2016
ABSTRACT Dental materials in general are tested in different animal models prior to the clinical use in humans, except for bleaching agents. Objectives To evaluate an experimental rat model for comparative studies of bleaching agents, by investigating the influence of different concentrations and appli...

Evaluation of an experimental rat model for comparative studies of bleaching agents

J. appl. oral sci; 24 (1), 2016
ABSTRACT Dental materials, in general, are tested in different animal models prior to their clinical use in humans, except for bleaching agents. Objectives To evaluate an experimental rat model for comparative studies of bleaching agents by investigating the influence of different concentrations and ap...

Uso y aplicaciones de la inmunohistoquímica con el anticuerpo anti-ghrelina para el estudio de la pulpa dentaria
Use and applications of immunohistochemistry with anti-ghrelin antibody for the study of dental pulp

La expresión de ghrelina se ha detectado a nivel de los tejidos dentarios, principalmente en los odontoblastos de la pulpa dentaria, células altamente especializadas -específicas del tejido pulpar- cuya función es la formación de la dentina. La nota técnica resume, en primer lugar, aspectos concept...

Immunohistochemical expression of TGF-β1 and osteonectin in engineered and Ca(OH)2-repaired human pulp tissues

Braz. oral res. (Online); 30 (1), 2016
Abstract The aim of the present study was to evaluate the expression of transforming growth factor-β1 (TGF-β1) and osteonectin (ON) in pulp-like tissues developed by tissue engineering and to compare it with the expression of these proteins in pulps treated with Ca(OH)2 therapy. Tooth slices we...

Chitosan-collagen biomembrane embedded with calcium-aluminate enhances dentinogenic potential of pulp cells

Braz. oral res. (Online); 30 (1), 2016
Abstract The development of biomaterials capable of driving dental pulp stem cell differentiation into odontoblast-like cells able to secrete reparative dentin is the goal of current conservative dentistry. In the present investigation, a biomembrane (BM) composed of a chitosan/collagen matrix embedded w...

Orthodontic movement in deciduous teeth

Deciduous teeth exfoliate as a result of apoptosis induced by cementoblasts, a process that reveals the mineralized portion of the root while attracting clasts. Root resorption in deciduous teeth is slow due to lack of mediators necessary to speed it up; however, it accelerates and spreads in one single ...

Expression of Mmp-20 in dental germs of human fetus

Int. j. morphol; 32 (4), 2014
During experiments in animal studies, it has been observed that enamelysin (MMP-20) is expressed during tooth development in the late secretory stage of amelogenesis but not in the mature enamel.The aim of this research was to determine the location of MMP-20 in human tooth germs in the different structu...