Abstract In the 1960s, organochlorine compounds were responsible for the decline of birds of prey populations such as Haliaee- tus leucocephalus and Falco peregrinus. Pesticides similar to DDT cause bioaccumulation in birds, affecting their eggshell com- position and compromising their development. Using...
Myocardial ischemia/reperfusion (MI/R) injury is a complex phenomenon that causes severe damage to the myocardium. However, the potential molecular mechanisms of MI/R injury have not been fully clarified. We identified potential molecular mechanisms and therapeutic targets in MI/R injury through analysis...
Hao, Kaiqiang;
Lin, Beisen;
Nian, Fuzhao;
Gao, Xi;
Wei, Zhong;
Luo, Gang;
Lu, Yachun;
Lan, Mingxian;
Yang, Jinguang;
Wu, Guoxing.
Phytophthora parasitica is an important oomycete that causes disease in a variety of plants, dimethomorph fungicides being specific for oomycetes. The aim of this study was to use RNA-seq to rapidly discover the mechanism by which dimethomorph acts in the treatment of P. parasitica. We found that the exp...
Fungicidas Industriales/farmacología,
Morfolinas/farmacología,
Phytophthora/efectos de los fármacos,
ARN Mensajero/biosíntesis,
RNA-Seq,
Proteínas Portadoras/biosíntesis,
Proteínas Portadoras/genética,
Permeabilidad de la Membrana Celular/efectos de los fármacos,
Permeabilidad de la Membrana Celular/genética,
Pared Celular/metabolismo,
Regulación de la Expresión Génica/efectos de los fármacos,
Ontología de Genes,
Estrés Oxidativo/genética,
Phytophthora/genética,
Enfermedades de las Plantas/parasitología,
ARN Mensajero/genética,
Especies Reactivas de Oxígeno,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Alineación de Secuencia,
beta-Glucanos/análisis
Previous study suggested that the southern stingray (Hypanus americanus) displays a marked ontogenetic shift in its habitat use in the Fernando de Noronha Archipelago (FNA), an attractive touristic spot in Brazil, that could be associated with changes in its feeding habits and foraging strategies. Here, ...
Abstract: Objective: To compare the genetic determinants involved in plant colonization or virulence in the reported genomes of K. variicola, K. quasipneumoniae and K. pneumoniae. Materials and methods: In silico comparisons and Jaccard analysis of genomic data were used. Fimbrial genes were detected...
Adaptación Biológica/genética,
Proteínas Bacterianas/genética,
Proteínas Bacterianas/fisiología,
Simulación por Computador,
Reservorios de Enfermedades,
Farmacorresistencia Bacteriana Múltiple,
Ontología de Genes,
Genes Bacterianos,
Genoma Bacteriano,
Klebsiella/enzimología,
Klebsiella/genética,
Klebsiella/patogenicidad,
Klebsiella/fisiología,
Infecciones por Klebsiella/microbiología,
Plantas/microbiología,
Virulencia/genética
We document for the first time the early ontogeny of Centropomus poeyi based on captive raised material representing 0-19 days posthatch (dph). The achievement of early developmental landmarks (i.e., yolk-sac depletion, flexion, development of fins) and changes in pigmentation are described (1.4 mm NL-10...
Li, YH;
Yang, Y;
Yan, YT;
Xu, LW;
Ma, HY;
Shao, YX;
Cao, CJ;
Wu, X;
Qi, MJ;
Wu, YY;
Chen, R;
Hong, Y;
Tan, XH;
Yang, L.
Occupational noise-induced hearing loss (ONIHL) is a prevalent occupational disorder that impairs auditory function in workers exposed to prolonged noise. However, serum microRNA expression in ONIHL subjects has not yet been studied. We aimed to compare the serum microRNA expression profiles in male work...
Biomarcadores/sangre,
Estudios de Casos y Controles,
Regulación de la Expresión Génica,
Ontología de Genes,
Pérdida Auditiva Provocada por Ruido/sangre,
Pérdida Auditiva Provocada por Ruido/genética,
MicroARNs/sangre,
MicroARNs/genética,
Proteína Quinasa 1 Activada por Mitógenos/análisis,
Enfermedades Profesionales/sangre,
Enfermedades Profesionales/genética,
Exposición Profesional/efectos adversos,
Reacción en Cadena en Tiempo Real de la Polimerasa
In this study, we screened differentially expressed genes in a multidrug-resistant isolate strain of Clostridium perfringens by RNA sequencing. We also separated and identified differentially expressed proteins (DEPs) in the isolate strain by two-dimensional electrophoresis (2-DE) and mass spectrometry (...
Proteínas Bacterianas/genética,
Proteínas Bacterianas/metabolismo,
Clostridium perfringens/clasificación,
Clostridium perfringens/efectos de los fármacos,
Clostridium perfringens/genética,
Clostridium perfringens/metabolismo,
ADN Complementario,
Farmacorresistencia Bacteriana Múltiple/genética,
Electroforesis en Gel Bidimensional/métodos,
Regulación Bacteriana de la Expresión Génica/genética,
Ontología de Genes,
Genes MDR,
Genoma Bacteriano/genética,
Espectrometría de Masas/métodos,
Proteoma/genética,
Análisis de Secuencia de ARN/métodos,
Transcriptoma/genética
PURPOSE: This aim of this study was to investigate the key genes and pathways involved in the response to pain in goat and sheep by transcriptome sequencing. METHODS: Chronic pain was induced with the injection of the complete Freund's adjuvant (CFA) in sheep and goats. The animals were divided into four...
Dolor Crónico/genética,
Ganglios Espinales/fisiopatología,
Transducción de Señal/genética,
Transcriptoma/genética,
Dolor Crónico/inducido químicamente,
Dolor Crónico/fisiopatología,
Umbral del Dolor/fisiología,
Transducción de Señal/fisiología,
Transcriptoma/fisiología,
Adyuvantes Inmunológicos,
Modelos Animales de Enfermedad,
Adyuvante de Freund,
Perfilación de la Expresión Génica,
Biblioteca de Genes,
Ontología de Genes,
Cabras,
Ovinos