Results: 26

Network prediction of the potential molecular mechanisms in birds of prey exposed to organochlorine pesticides

Acta toxicol. argent; 28 (1), 2020
Abstract In the 1960s, organochlorine compounds were responsible for the decline of birds of prey populations such as Haliaee- tus leucocephalus and Falco peregrinus. Pesticides similar to DDT cause bioaccumulation in birds, affecting their eggshell com- position and compromising their development. Using...

Identification of potential molecular mechanisms and small molecule drugs in myocardial ischemia/reperfusion injury

Braz. j. med. biol. res; 53 (9), 2020
Myocardial ischemia/reperfusion (MI/R) injury is a complex phenomenon that causes severe damage to the myocardium. However, the potential molecular mechanisms of MI/R injury have not been fully clarified. We identified potential molecular mechanisms and therapeutic targets in MI/R injury through analysis...

RNA-seq analysis of the response of plant-pathogenic oomycete Phytophthora parasitica to the fungicide dimethomorph

Rev. argent. microbiol; 51 (3), 2019
Phytophthora parasitica is an important oomycete that causes disease in a variety of plants, dimethomorph fungicides being specific for oomycetes. The aim of this study was to use RNA-seq to rapidly discover the mechanism by which dimethomorph acts in the treatment of P. parasitica. We found that the exp...

Unravelling the foraging behavior of the southern stingray, Hypanus americanus (Myliobatiformes: Dasyatidae) in a Southwestern Atlantic MPA

Neotrop. ichthyol; 17 (2), 2019
Previous study suggested that the southern stingray (Hypanus americanus) displays a marked ontogenetic shift in its habitat use in the Fernando de Noronha Archipelago (FNA), an attractive touristic spot in Brazil, that could be associated with changes in its feeding habits and foraging strategies. Here, ...

Klebsiella variicola and Klebsiella quasipneumoniae with capacity to adapt to clinical and plant settings

Salud pública Méx; 60 (1), 2018
Abstract: Objective: To compare the genetic determinants involved in plant colonization or virulence in the reported genomes of K. variicola, K. quasipneumoniae and K. pneumoniae. Materials and methods: In silico comparisons and Jaccard analysis of genomic data were used. Fimbrial genes were detected...

Larval development of the Mexican Snook, Centropomus poeyi (Teleostei: Centropomidae)

Neotrop. ichthyol; 16 (1), 2018
We document for the first time the early ontogeny of Centropomus poeyi based on captive raised material representing 0-19 days posthatch (dph). The achievement of early developmental landmarks (i.e., yolk-sac depletion, flexion, development of fins) and changes in pigmentation are described (1.4 mm NL-10...

Analysis of serum microRNA expression in male workers with occupational noise-induced hearing loss

Braz. j. med. biol. res; 51 (3), 2018
Occupational noise-induced hearing loss (ONIHL) is a prevalent occupational disorder that impairs auditory function in workers exposed to prolonged noise. However, serum microRNA expression in ONIHL subjects has not yet been studied. We aimed to compare the serum microRNA expression profiles in male work...

Determination of multidrug resistance mechanisms in Clostridium perfringens type A isolates using RNA sequencing and 2D-electrophoresis

Braz. j. med. biol. res; 51 (8), 2018
In this study, we screened differentially expressed genes in a multidrug-resistant isolate strain of Clostridium perfringens by RNA sequencing. We also separated and identified differentially expressed proteins (DEPs) in the isolate strain by two-dimensional electrophoresis (2-DE) and mass spectrometry (...

Identification of key genes and pathways involved in response to pain in goat and sheep by transcriptome sequencing

Biol. Res; 51 (), 2018
PURPOSE: This aim of this study was to investigate the key genes and pathways involved in the response to pain in goat and sheep by transcriptome sequencing. METHODS: Chronic pain was induced with the injection of the complete Freund's adjuvant (CFA) in sheep and goats. The animals were divided into four...