Resumen Introducción: PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy) Es una técnica que, vía laparoscopía, permite administrar quimioterapia en aerosol intraperitoneal, para el tratamiento de la carcinomatosis, ya sea para disminuir masa tumoral y aumentar la resecabilidad, o como paliació...
ABSTRACT Purpose: This study aimed to optimize the effective doses of mitomycin C, 5-fluorouracil, and their combination on cultivated basal cell carcinoma. Methods: Cultivated basal cell carcinoma and fibroblastic cells were treated with different concentrations of mitomycin C, 5-fluorouracil, and the...
Quimioterapia neoadyuvante (NAC) en cáncer de mama permite conocer la sensibilidad del tumor al tratamiento, alcanzar respuesta patológica completa (pRC), está asociada a mejor supervivencia en cáncer de mama localmente avanzado. El objetivo de este estudio fue conocer el impacto de la pRC en la supe...
Background: Central nervous system international prognosis index (CNS-IPI) is validated in European and the USA cancer databases. However, no validation has been done in Mexican population. Objective: The objective of the study was to assess the impact of the CNS-IPI on central nervous system (CNS) rela...
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico,
Sistema Nervioso Central,
Neoplasias del Sistema Nervioso Central/tratamiento farmacológico,
Ciclofosfamida/uso terapéutico,
Doxorrubicina/uso terapéutico,
Linfoma de Células B Grandes Difuso/tratamiento farmacológico,
México/epidemiología,
Recurrencia Local de Neoplasia,
Prednisona/uso terapéutico,
Pronóstico,
Estudios Retrospectivos,
Rituximab/uso terapéutico,
Vincristina/uso terapéutico
SUMMARY OBJECTIVE: The aim of this study was to examine the characteristics of patients admitted to our hospital with a diagnosis of breast cancer who reached pathological complete response after being operated following eight cycles of neoadjuvant chemotherapy. METHODS: Between 2015-2020, patients w...
Abstract Complete hydatidiform mole (CHM) is a rare type of pregnancy, in which 15 to 20% of the cases may develop into gestational trophoblastic neoplasia (GTN). The diagnostic of GTN must be done as early as possible through weekly surveillance of serum hCG after uterine evacuation.We report the case o...
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico,
Malformaciones Arteriovenosas/complicaciones,
Ciclofosfamida/uso terapéutico,
Dactinomicina/uso terapéutico,
Embolización Terapéutica,
Etopósido/uso terapéutico,
Enfermedad Trofoblástica Gestacional/complicaciones,
Enfermedad Trofoblástica Gestacional/diagnóstico por imagen,
Enfermedad Trofoblástica Gestacional/tratamiento farmacológico,
Metotrexato/uso terapéutico,
Embarazo de Alto Riesgo,
Ultrasonografía Prenatal,
Arteria Uterina,
Hemorragia Uterina/diagnóstico por imagen,
Hemorragia Uterina/etiología,
Hemorragia Uterina/terapia,
Vincristina/uso terapéutico
SUMMARY Anaplastic thyroid carcinoma is the rarest tumor of the thyroid gland, representing less than 2% of clinically recognized thyroid cancers. Typically, it has an extremely rapid onset, fatal outcomes in most cases, and a median overall survival of 3 to 10 months despite aggressive multidisciplinary...
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico,
COVID-19,
Imidazoles,
Mutación,
Oximas,
Pandemias,
Proteínas Proto-Oncogénicas B-raf/genética,
Pirimidinonas,
SARS-CoV-2,
Carcinoma Anaplásico de Tiroides/tratamiento farmacológico,
Carcinoma Anaplásico de Tiroides/genética,
Neoplasias de la Tiroides/tratamiento farmacológico,
Piridonas
Testa, Laura;
Mano, Max;
Arai, Roberto Jun;
Bonadio, Renata Colombo;
Serrano, Sergio V.;
Zorzetto, Marina M Costa;
Crocamo, Susanne;
Smaletz, Oren;
Freitas-Junior, Ruffo;
Hoff, Paulo M..
OBJECTIVES: The Lewis-Y antigen is expressed in 44%-90% of breast cancers (BCs). The expression of the antigen in carcinoma tissue differs from that in normal tissues. This study aimed to evaluate the clinical benefit of the humanized anti-Lewis Y monoclonal antibody, hu3S193, in advanced hormone recepto...
Harada, Guilherme;
Neffa, Maria Fernanda Batistuzzo Vicentini;
Bonadio, Renata Colombo;
Mendoza, Elizabeth Zambrano;
Caparica, Rafael;
Lauricella, Letícia Leone;
Takagaki, Teresa Yae;
Roitberg, Felipe Santa Rosa;
Terra, Ricardo Mingarini;
Castro Jr, Gilberto De.
ABSTRACT Objective: Adjuvant chemotherapy (AC) improves survival of patients with resected non-small cell lung cancer (NSCLC). However, the cisplatin-vinorelbine regimen has been associated with a significant risk of clinically relevant toxicity. We sought to evaluate the effectiveness, safety, and feas...
ABSTRACT Objective: To describe the case of a child who presented hemophagocytic lymphohistiocytosis (HLH) associated with acute monocytic leukemia after chemotherapy, with hemophagocytosis caused by leukemic cells. Case description: In a university hospital in Southern Brazil, a 3-year-old female wa...
Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos,
Brasil,
Resultado Fatal,
Leucemia Monocítica Aguda/diagnóstico,
Leucemia Monocítica Aguda/tratamiento farmacológico,
Leucemia Monocítica Aguda/genética,
Leucemia Monocítica Aguda/patología,
Linfohistiocitosis Hemofagocítica/diagnóstico,
Linfohistiocitosis Hemofagocítica/etiología,
Linfohistiocitosis Hemofagocítica/inmunología,
Linfohistiocitosis Hemofagocítica/patología
