Abstract The study is aimed to develop a monolithic controlled matrix transdermal patches containing Metoclopramide as a model drug by solvent casting method. Eudragit L100, Polyvinylpyrrolidone K-30, and Methylcellulose were used in different ratios and Polyethylene glycol 400 added as a plasticizer. Re...
Introdução: Os fios Copper Ni-Ti (CuNiTi) possuem indicações de uso clínico específicas,
permanecendo no ambiente bucal por um longo período. Por esse motivo suas
características mecânicas, termodinâmicas e estruturais devem ser preservadas durante
todo o período de uso. Objetivos: Investigar ...
Diante das exigências crescentes das agências regulatórias do mundo todo quanto à redução/eliminação de ácidos graxos trans nos alimentos industrializados, bem como da conscientização do consumidor sobre a relação entre alimentação e saúde, o desenvolvimento de alternativas mais saudávei...
A baixa solubilidade aquosa dos insumos farmacêuticos ativos (IFA) é um grande desafio no desenvolvimento de formulações farmacêuticas, pois pode resultar em biodisponibilidade insuficiente e variável. Diversas estratégias de modificação do estado sólido dos compostos ativos, têm sido proposta...
Poloxámero/análogos & derivados,
Insumos Farmacéuticos,
Análisis Espectral/instrumentación,
Análisis de Fourier,
ADN Polimerasa Dirigida por ARN/efectos adversos,
Derivados de la Hipromelosa/metabolismo,
Disolución,
Espectroscopía Infrarroja por Transformada de Fourier,
Preparaciones Farmacéuticas/administración & dosificación,
Terapia Antirretroviral Altamente Activa/instrumentación,
Rastreo Diferencial de Calorimetría/métodos
Abstract The present study focused on the use of pineapple plant stem, which is an agro-waste, for the production of starch (11.08 % ± 0.77). Characters were studied using X-ray diffraction, nuclear magnetic resonance spectroscopy (NMR), fourier transform infrared spectroscopy (FTIR), scanning electron ...
Buccal route of administration has many advantages such as improving patient compliance, bypassing the GIT and hepatic first pass effect. The objectives are to formulate mucoadhesive buccal tablet using Mefenamic acid and compatible excipients, and to evaluate the product using quality control tests and ...
Abbas, Nasir;
Irfan, Muhammad;
Zahoor, Ameer Fawad;
Khan, Ikram Ullah;
Syed, Haroon Khalid;
Rasul, Akhtar;
Hussain, Amjad;
Arshad, Mohammad Sohail;
Mohsin, Noor ul amin;
Iqbal, Furqan Muhammad;
Qayyum, Muhammad Abdul.
The aim of present work was to investigate blends of Eudragit® NE 30D with Aquacoat® ECD using different ratios to eliminate curing effect associated with individual polymers. Propranolol HCl 10% w/w was layered onto sugar cores using 5% w/w HPMC as a binder. Drug-layered-cores were coated either with ...
Tolmetin sodium (TS) is a powerful non-steroidal mitigating drug for the treatment of rheumatoid joint inflammation, osteoarthritis, and adolescent rheumatoid joint pain. In addition to its gastrointestinal (GIT) problems, TS has a short biological half-life (1 hr). In a trial to overcome these side effe...
It has been hypothesized that the therapeutic effects of artepillin C, a natural compound derived from Brazilian green propolis, are likely related to its partition in the lipid bilayer component of biological membranes. To test this hypothesis, we investigated the effects of the major compound of green ...
2-Naftilamina/análogos & derivados,
Rastreo Diferencial de Calorimetría,
Colesterol/química,
Lauratos,
Membrana Dobles de Lípidos/química,
Liposomas/química,
Microscopía Confocal,
Microscopía Fluorescente,
Modelos Químicos,
Fenilpropionatos/química,
Valores de Referencia,
Reproducibilidad de los Resultados,
Dispersión del Ángulo Pequeño,
Temperatura,
Factores de Tiempo
