Results: 1561

E-cadherin and NF-κB expression in the vagina after ovarian ischemia and reperfusion

Acta cir. bras; 39 (), 2024
Purpose: To investigate inflammation and cell adhesion molecules in the vagina after ovarian ischemia-reperfusion (IR) injury. Methods: 20 Wistar albino female rats were divided into two groups: control, and IR groups. In IR group, blood flow was restricted for 2 hours for ovarian ischemia. Then, tissues...

Metabolic and ultrastructural renal changes in adult Wistar rats fed by a cafeteria diet

Acta cir. bras; 39 (), 2024
Purpose: To evaluate, by quantitative and qualitative methods, the glomerular ultrastructure in Wistar rats fed a cafeteria diet. Methods: Male Wistar rats were divided into two groups at 21 days of age: control (C, n = 10) and cafeteria diet (CAF, n = 8). The animals were followed up until 5 months of a...

Caffeine mitigates tamoxifen-induced fatty liver in Wistar rats

Acta cir. bras; 39 (), 2024
Purpose: Tamoxifen, a widely used drug for breast cancer treatment, is associated with adverse effects on the liver, including the development of fatty liver. This study aimed to investigate the potential protective effect of caffeine against tamoxifen-induced fatty liver in Wistar rats. Methods: Rats we...

Preclinical study of experimental burns treated with photobiomodulation and Human Amniotic Membrane, both isolated and associated

Abstract Objective: to evaluate the effect of photobiomodulation with low-level 660 nm laser alone or associated with Human Amniotic Membrane in the repair of partial-thickness burns in rats. Method: an experimental study conducted with 48 male Wistar rats, randomized into four groups: Control, Human ...

In vivo Gonadoprotective Effects of Myricetin on Cisplatin- Induced Testicular Damage via Suppression of TLR4/NF-kB Inflammation Pathway and Heat-Shock Response

Int. j. morphol; 41 (6), 2023
SUMMARY: The aim of this study is to reveal the gonadoprotective effects of myricetin (MYC), which has many biological properties, on cisplatin (CP)-induced testicular damage in rats. For this purpose, 40 male Wistar albino rats were divided into 4 groups as Control (group given no treatment), MYC (group...

Therapeutic effect of biosynthesized silver nanoparticles on hypothyroidism induced in albino rats

BACKGROUND In this study, silver nanoparticles (AgNPs) were biosynthesized using Rhizopus oryzae. The therapeutic effect of AgNP treatment protocols for hypothyroidism induced in male albino rats via biochemical as well as hematological parameters, thyroid profile, and androgen male sex hormone (testoste...

Interleukin-37 has A Promising Cardioprotective Effect on Isoproterenol-Induced Myocardial Infarction

Int. j. morphol; 41 (5), 2023
SUMMARY: The main cause of mortality and disability globally is myocardial infarction (MI). Isoproterenol (ISO), a β-adrenoceptor agonist, has been used to induce rat myocardial necrosis. Whereas interleukin-37 (IL-37) has anti-inflammatory and cytoprotective properties. The study aimed to investiga...

Protective Effects and Mechanisms of Huangqi Decoction Against Radiation-Induced Bystander Effects

Int. j. morphol; 41 (5), 2023
SUMMARY: The 12C6+ heavy ion beam irradiation can cause bystander effects. The inflammatory cytokines, endocrine hormones and apoptotic proteins may be involved in 12C6+ irradiation-induced bystander effects. This study characterized the protective effects and mechanisms of Huangqi decoction (HQD) agains...

Postnatal Exposure to Exogenous progesterone Exacerbates the Prenatally-Induced Abnormal Sperms Production and Function in Rats

Int. j. morphol; 41 (4), 2023
SUMMARY: This study aimed at clarifying the impact of long-term prenatal and postnatal exposure to exogenous progesterone on sperm production and function, relative sex organs weights, and the levels of the relevant hormones in rats. Sixty male Wistar rats were included and classified into three groups (...

Investigation of the Neuro-Regenerative Effects of Bioresonance and Magnetotherapy in Sciatic Nerve Damage-Induced Rats

Int. j. morphol; 41 (4), 2023
SUMMARY: Peripheral nerve damage is a significant clinical problem that can lead to severe complications in patients. Regarding the regeneration of peripheral nerves, it is crucial to use experimental animals' nerves and use different evaluation methods. Epineural or perineural suturing is the gold stand...