LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Comparative effects of vitamin C on the effects of local anesthetics ropivacaine, bupivacaine, and lidocaine on human chondrocytes

Tian, Jun; Li, Yan.

Rev. bras. anestesiol; 66 (1), 2016

BACKGROUND: Intra-articular injections of local anesthetics are commonly used to enhance post-operative analgesia following orthopedic surgery as arthroscopic surgeries. Nevertheless, recent reports of severe complications due to the use of intra-articular local anesthetic have raised concerns. OBJECTIVE...

Amidas/toxicidad, Anestésicos Locales/toxicidad, Antioxidantes/administración & dosificación, Antioxidantes/farmacología, Apoptosis/efectos de los fármacos, Ácido Ascórbico/administración & dosificación, Ácido Ascórbico/farmacología, Bupivacaína/toxicidad, Caspasa 3/genética, Caspasa 9/genética, Células Cultivadas, Condrocitos/efectos de los fármacos, Condrocitos/patología, Relación Dosis-Respuesta a Droga, Regulación hacia Abajo/efectos de los fármacos, Citometría de Flujo, Lidocaína/toxicidad, Especies Reactivas de Oxígeno/metabolismo, Ropivacaína

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Caffeine teratogenicity in rats: morphological characterization and hypothesized mechanisms

Souza, Ana Cláudia de; Dussán-Sarria, Jairo Alberto; Souza, Andressa de; Caumo, Wolnei; Torres, Iraci Lucena da Silva.

Clin. biomed. res; 36 (4), 2016

Caffeine consumption during pregnancy has been shown in the scientific literature to be associated with teratogenicity such as low birth weight, fetal malformations, and miscarriage. However, the morphological alterations of the offspring of dams exposed during pregnancy have not been consistently descri...

Embarazo, Intercambio Materno-Fetal/efectos de los fármacos, Cafeína/administración & dosificación, Regulación hacia Abajo/efectos de los fármacos, Receptor de Adenosina A1, Anomalías Congénitas, Cardiopatías Congénitas/inducido químicamente, Cafeína/toxicidad

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Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells

Bae, Seunghee; Lim, Kyung Mi; Cha, Hwa Jun; An, In-Sook; Lee, Jeong Pyo; Lee, Kwang Sik; Lee, Ghang Tai; Lee, Kun Kook; Jung, Ho Jung; Ahn, Kyu Joong; An, Sungkwan.

Biol. Res; 47 (), 2014

BACKGROUND: Accumulating evidence indicates that reactive oxygen species (ROS) are an important etiological factor for the induction of dermal papilla cell senescence and hair loss, which is also known alopecia. Arctiin is an active lignin isolated from Arctium lappa and has anti-inflammation, anti-micro...

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