Oropouche virus (OROV) is an arthropod-borne virus of the Peribunyaviridae family, transmitted to humans primarily by Culicoides paraensis. It is one of the main arboviruses infecting humans in Brazil, primarily in the Amazon Region. Here, we report the detection of OROV in the saliva and urine of a pati...
Secuencia de Aminoácidos,
Secuencia de Bases,
Infecciones por Bunyaviridae/diagnóstico,
Persona de Mediana Edad,
Orthobunyavirus/genética,
Orthobunyavirus/aislamiento & purificación,
Filogenia,
ARN Viral/genética,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
Saliva/virología,
Orina/virología
Paracoccidioides spp. isolation from environmental samples is rare and hardly reproducible. Molecular techniques have facilitated the fungal detection. However, it can be still difficult. Some strategies to enhance the capacity of DNA detection have been adopted, including the analysis of soil samples be...
Armadillos,
Secuencia de Bases,
Brasil,
ADN de Hongos/genética,
Ecosistema,
Paracoccidioides/genética,
Paracoccidioides/crecimiento & desarrollo,
Paracoccidioides/aislamiento & purificación,
Paracoccidioidomicosis/microbiología,
Análisis de Secuencia de ADN,
Microbiología del Suelo
BACKGROUND The Nyssomyia genus and Lutzomyia subgenus include medical important species that are Latin American leishmaniases vectors. Little is known about the phylogenetic relationships of closely-related species in each of these taxonomic groups that are morphologically indistinguishable or different...
Background: Protein glutaminase specifically deamidates glutamine residue in protein and therefore significantly improves protein solubility and colloidal stability of protein solution. In order to improve its preparation efficiency, we exploited the possibility for its secretory expression mediated by t...
Bacillus licheniformis/enzimología,
Bacillus subtilis,
Escherichia coli,
Glutaminasa/metabolismo,
Glutaminasa/genética,
Señales de Clasificación de Proteína,
Arginina,
Prostaglandinas A/química,
Bacillus licheniformis/genética,
Secuencia de Bases,
Plásmidos,
Mutagénesis Sitio-Dirigida,
Ácido Aspártico
Abstract Introduction: Salmonella Enteritidis is a major cause of human salmonellosis in the world, with contaminated eggs and raw chicken meat as the main routes of infection. The main Salmonella spp. serovars circulating in laying hen farms, the surface of eggs, and in raw chicken carcasses have been ...
ADN Bacteriano/genética,
Gastroenteritis/microbiología,
Enfermedades de las Aves de Corral/microbiología,
Intoxicación Alimentaria por Salmonella/microbiología,
Salmonelosis Animal/microbiología,
Salmonella enteritidis/genética,
Secuencia de Bases,
Colombia/epidemiología,
Estudios Transversales,
Farmacorresistencia Microbiana,
Cáscara de Huevo/microbiología,
Heces/microbiología,
Gastroenteritis/epidemiología,
Gastroenteritis/veterinaria,
Tipificación de Secuencias Multilocus,
Filogenia,
Aves de Corral,
Enfermedades de las Aves de Corral/epidemiología,
Intoxicación Alimentaria por Salmonella/epidemiología,
Salmonelosis Animal/epidemiología,
Salmonella enteritidis/clasificación,
Salmonella enteritidis/efectos de los fármacos,
Salmonella enteritidis/aislamiento & purificación,
Análisis de Secuencia de ADN,
Serogrupo
The present study aimed to identify microRNAs (miRNAs) that are involved in neuropathic pain and predict their corresponding roles in the pathogenesis and development process of neuropathic pain. The rat model of neuropathic pain caused by spared nerve injury (SNI) was established in Sprague-Dawley male ...
Human bocaviruses (HBoV) are mainly associated with respiratory and gastroenteric infections. These viruses belong to the family Parvoviridae, genus Bocaparvovirus and are classified in four subtypes (HBoV1-4). Recombination and point mutation have been described as basis of parvovirus evolution. In this...
Knijn, Nikki;
Water, Carlijn van de;
Vliet, Shannon van;
Meijer, Jos;
Riemersma, Sietske;
Tebar, Maria;
Punt, Cornelis;
Mekenkamp, Leonie;
Simmer, Femke;
Nagtegaal, Iris.
Background: Mutations in the RAS/RAF pathway predict resistance to anti-epidermal growth factor receptor
antibodies in colorectal cancer (CRC), and may be targets for future therapies. This study investigates concordance
of BRAF, HRAS, KRAS, NRAS and PIK3CA mutation status in primary CRC with matched liv...
Neoplasias Colorrectales/genética,
Neoplasias Hepáticas/genética,
Neoplasias Pulmonares/genética,
Proteínas ras/genética,
Proteínas Proto-Oncogénicas B-raf/genética,
Neoplasias Colorrectales/patología,
Neoplasias Hepáticas/secundario,
Neoplasias Pulmonares/secundario,
Secuencia de Bases,
Mutación/genética,
Secuenciación de Nucleótidos de Alto Rendimiento
El cáncer de cuello uterino es el segundo cáncer femenino más común a nivel mundial. El agente causal es el virus de papiloma humano (VPH). Se han identificado 13 tipos de virus de papiloma humano de alto riesgo oncogénico (VPH-AR), entre los cuales el VPH 16 y VPH 18 son los más frecuentemente det...
ABSTRACT BACKGROUND: Norovirus (NoV) is an important etiologic agent of acute gastroenteritis and infects individuals of all ages, especially children in Brazil and worldwide. NoV GII.4 was the most prevalent genotype worldwide because of your extensive genetic diversity. In Brazil, especially in the N...
Enfermedad Aguda,
Secuencia de Bases,
Brasil,
Infecciones por Caliciviridae/virología,
Gastroenteritis/virología,
Variación Genética,
Genotipo,
Persona de Mediana Edad,
Epidemiología Molecular,
Norovirus/genética,
Norovirus/aislamiento & purificación,
Filogenia,
ARN Viral,
Valores de Referencia,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
