La morfea ampollar es un tipo enfrecente de esclerodermia localizada que se caracteriza por presentar ampollas sobre placas escleróticas. La presencia de este tipo de lesiones obliga a descartar la variante extraenital de liquen esclerodemias localizadas, es posible hallar ambas afecciones. Se describe ...
ABSTRACT BACKGROUND: Immunosuppressive drugs have important role in transplant of solid grafts, it aim avoid episodes of acute and chronic rejection and improving graft survival and patient survival. In Brazil, in 2016, liver transplantation was the third most frequent, with 1,880 transplants performed...
Abstract Background: Tacrolimus is used to prevent unaesthetic scars due to its action on fibroblast activity and collagen production modulation. Objectives: To evaluate the action pathways, from the histopathological point of view and in cytokine control, of tacrolimus ointment in the prevention of hy...
ABSTRACT BACKGROUND: The use of immunosuppressive drugs after liver transplantation (LT) is associated with the development of systemic arterial hypertension (SAH), in addition to other comorbidities of metabolic syndrome. OBJECTIVE: Therefore, the purpose of this study was to analyze the time after ...
ABSTRACT The authors present a case of lupus miliaris disseminatus faciei , a rare skin disease of unknown etiology, which may cause unaesthetic scarring due to its difficult treatment. The histopathological examination of epithelioid granulomas with caseating necrosis, together with the clinical feature...
Dermatosis Facial/patología,
Dermatosis Facial/tratamiento farmacológico,
Rosácea/patología,
Rosácea/tratamiento farmacológico,
Granuloma/patología,
Granuloma/tratamiento farmacológico,
Enfermedades de los Párpados/patología,
Enfermedades de los Párpados/tratamiento farmacológico,
Lupus Vulgar/patología,
Lupus Vulgar/tratamiento farmacológico,
Cicatriz,
Tetraciclina/uso terapéutico,
Isotretinoína/uso terapéutico,
Dapsona/uso terapéutico,
Tacrolimus/uso terapéutico,
Prednisona/uso terapéutico,
Minociclina/uso terapéutico
El uso de inhibidores de calcineurina, en particular de tacrolimus como terapia inmunosupresora se ha generalizado a nivel mundial, permitiendo mejorar la tasa de sobrevida del injerto y la calidad de vida del paciente trasplantado. Con el acceso a los estudios de farmacogenética, los grupos de trasplan...
Tacrolimus (TAC), a calcineurin inhibitor, and everolimus (EVL), an mTOR inhibitor, have been used as immunosuppressive (ISS) drugs in post-kidney transplantation therapy. The objective of this study was to compare the efficacy of EVL vs TAC in the ISS maintenance triple therapy. Ninety-seven kidney tran...
Tustumi, Francisco;
Miranda Neto, Antonio Afonso de;
Silveira Júnior, Sérgio;
Fernandes, Felipe Alexandre;
Silva, Miller Barreto de Brito e;
Ernani, Lucas;
Nacif, Lucas Souto;
Coelho, Fabricio Ferreira;
Andraus, Wellington;
Bernardo, Wanderley Marques;
Herman, Paulo;
Carneiro-DAlbuquerque, Luiz Augusto.
A combination of immunosuppressants may improve outcomes due to the synergistic effect of their different action mechanisms. Currently, there is no consensus regarding the best immunosuppressive protocol after liver transplantation. This review aimed to evaluate the effectiveness and safety of tacrolimus...
ABSTRACT Objective The aim of this study was to evaluate patients with complete response of oral chronic graft-versus-host disease to immunosuppressive treatment. Methods A total of 29 patients submitted to allogeneic hematopoietic stem cell transplantation, with oral chronic graft-versus-host diseas...
O Informe Diário de Evidências é uma produção do Ministério da Saúde que tem como objetivo acompanhar diariamente as publicações científicas sobre tratamento farmacológico e vacinas para a COVID-19. Dessa forma, são realizadas buscas estruturadas em bases de dados biomédicas, referentes ao d...
Infecciones por Coronavirus/tratamiento farmacológico,
Neumonía Viral/tratamiento farmacológico,
Betacoronavirus/efectos de los fármacos,
Corticoesteroides/uso terapéutico,
Ribavirina/uso terapéutico,
Células Madre Mesenquimatosas,
Hidroxicloroquina/uso terapéutico,
Ácido Micofenólico/uso terapéutico,
Tacrolimus/uso terapéutico,
Prednisolona/uso terapéutico,
Meropenem/uso terapéutico,
Combinación Trimetoprim y Sulfametoxazol/uso terapéutico,
Ácido Fólico/uso terapéutico,
Ácido Ursodesoxicólico/uso terapéutico,
Lopinavir/uso terapéutico,
Ritonavir/uso terapéutico,
Cloroquina/uso terapéutico,
Interferón-alfa/uso terapéutico,
Azitromicina/uso terapéutico,
Inmunoglobulinas/uso terapéutico,
Anticuerpos Monoclonales/uso terapéutico,
Anticuerpos Neutralizantes/uso terapéutico,
Evaluación de la Tecnología Biomédica,
Estudios de Cohortes,
Estudios Transversales
