Shimabuco, Andrea Yukie;
Medeiros-Ribeiro, Ana Cristina de;
Miossi, Renata;
Bonfiglioli, Karina Rossi;
Moraes, Julio Cesar Bertacini de;
Gonçalves, Celio Roberto;
Sampaio-Barros, Percival Degrava;
Goldenstein-Schainberg, Claudia;
Souza, Fernando Henrique Carlos de;
Prado, Leandro Lara do;
Ugolini-Lopes, Michele Remião;
Yuki, Emily Figueiredo Vieira Neves;
Bonfa, Eloisa;
Saad, Carla Gonçalves Schahin.
OBJECTIVES: To retrospectively evaluate the performance and distinctive pattern of latent tuberculosis (TB) infection (LTBI) screening and treatment in patients with ankylosing spondylitis (AS) and psoriatic arthritis (PsA) under anti-tumor necrosis factor (TNF) therapy and determine the relevance of re-...
Araujo, Zaida;
Palacios, Andrea;
Enciso-Moreno, Leonor;
Lopez-Ramos, Juan Ernesto;
Wide, Albina;
Waard, Jacobus Henri de;
Rivas-Santiago, Bruno;
Serrano, Carmen Judith;
Bastian-Hernandez, Yadira;
Castañeda-Delgado, Julio Enrique;
Enciso-Moreno, Jose Antonio.
Abstract INTRODUCTION: Biomarkers are critical tools for finding new approaches for controlling the spread of tuberculosis (TB), including for predicting the development of TB therapeutics, vaccines, and diagnostic tools. METHODS: Expression of immune biomarkers was analyzed in peripheral blood cells...
ABSTRACT Objective: To describe the incidence of active tuberculosis and the occurrence of adverse events after isoniazid treatment in patients with latent tuberculosis infection (LTBI) who also had chronic inflammatory diseases and were treated with immunobiologic agents in an endemic area in Brazil. ...
Profilaxis Antibiótica/métodos,
Antituberculosos/uso terapéutico,
Brasil/epidemiología,
Enfermedades Endémicas,
Factores Inmunológicos/uso terapéutico,
Inmunosupresores/uso terapéutico,
Isoniazida/uso terapéutico,
Tuberculosis Latente/diagnóstico,
Tuberculosis Latente/tratamiento farmacológico,
Tuberculosis Latente/epidemiología,
Análisis Multivariante,
Estudios Prospectivos,
Radiografía Torácica,
Factores de Riesgo,
Factores de Tiempo,
Resultado del Tratamiento,
Prueba de Tuberculina/métodos
ABSTRACT Most people infected by Mycobacterium tuberculosis (Mtb) do not have any signs or disease symptoms, a condition known as latent tuberculosis infection (LTBI). The introduction of biological agents, mainly tumor necrosis factor (TNF) inhibitors, for the treatment of immune-mediated diseases such ...
Corrêa, Raquel da Silva;
Rodrigues, Luciana Silva;
Pereira, Leticia Hagge Lima;
Nogueira, Otto Castro;
Leung, Janaína;
Sousa, Marcela da S;
Hacker, Mariana de Andrea;
Siqueira, Helio Ribeiro de;
Capone, Domênico;
Alves, Rogério Lopes Rufino;
Pessolani, Maria Cristina Vidal;
Schmitz, Veronica;
Pereira, Geraldo Moura Batista.
BACKGROUND CD64 (FcγR1) is a high-affinity receptor for monomeric IgG1 and IgG3. Circulating neutrophils express very low amounts of CD64 on their surface. OBJECTIVES Our primary aim was to investigate the utility of neutrophil CD64 surface expression as a biomarker of active pulmonary tuberculos...
ABSTRACT Objective: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemographic, behavioral, and clinical associations with positive tuberculin skin test (TST) results. Methods: This was a cross-sectional study of patien...
ABSTRACT Objective: To describe the characteristics of patients diagnosed with tuberculosis and latent tuberculosis infection. Methods: A retrospective study, between 2012 and 2015, with data from patients of Programa Einstein na Comunidade de Paraisópolis. To evaluate possible factors associated with...
Distribución por Edad,
Brasil/epidemiología,
Tuberculosis Latente/diagnóstico,
Tuberculosis Latente/epidemiología,
Mycobacterium tuberculosis/aislamiento & purificación,
Radiografía Torácica,
Estudios Retrospectivos,
Distribución por Sexo,
Estadísticas no Paramétricas,
Tomógrafos Computarizados por Rayos X,
Prueba de Tuberculina/estadística & datos numéricos,
Tuberculosis Pulmonar/diagnóstico,
Tuberculosis Pulmonar/epidemiología
ABSTRACT Objective: To estimate the prevalence of and determine the risk factors associated with latent Mycobacterium tuberculosis infection (LTBI) among primary health care workers in the city of Vitória, Brazil. Methods: This was a cross-sectional study with data collected through a survey regarding...
Brasil/epidemiología,
Estudios Transversales,
Personal de Salud/estadística & datos numéricos,
Tuberculosis Latente/diagnóstico,
Tuberculosis Latente/epidemiología,
Tuberculosis Latente/microbiología,
Tuberculosis Latente/prevención & control,
Mycobacterium tuberculosis/aislamiento & purificación,
Enfermedades Profesionales/diagnóstico,
Enfermedades Profesionales/epidemiología,
Enfermedades Profesionales/microbiología,
Enfermedades Profesionales/prevención & control,
Prevalencia,
Factores de Riesgo,
Prueba de Tuberculina
Los fármacos anti factor de necrosis tumoral alfa (TNF-α) bloquean una de las citoquinas implicadas en la patogénesis de la Enfermedad Inflamatoria intestinal (EII). Su uso se relaciona con aumento de tuberculosis (TB), por lo que el despistaje previo es obligatorio. En la infección tuberculosa laten...
Tuberculosis Latente/diagnóstico,
Tuberculosis Latente/tratamiento farmacológico,
Isoniazida/efectos adversos,
Antituberculosos/efectos adversos,
Infliximab/efectos adversos,
Fármacos Gastrointestinales/efectos adversos,
Edema/inducido químicamente,
Erupciones por Medicamentos,
Enfermedad de Crohn/tratamiento farmacológico,
Dermatosis Facial/inducido químicamente,
Exantema/inducido químicamente,
Tuberculosis Latente/inducido químicamente
