Results: 66

Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil

J. bras. pneumol; 46 (2), 2020
ABSTRACT Objective: To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. Methods: This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hospita...

Relationship between multimorbidity and the outcome of the treatment for pulmonary tuberculosis

ABSTRACT Objective: To analyze the influence of multimorbidity on the treatment outcome of new cases of pulmonary tuberculosis. Method: A population-based analytical study, using secondary data, collected from the database of the Notification Disease Information System, of new cases of pulmonary tube...

Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST

Braz. j. infect. dis; 23 (6), 2019
ABSTRACT Setting: Treatment of tuberculosis (TB) can result in Drug-Induced Liver Injury (DILI) since hepatotoxic metabolites are formed during the biotransformation of isoniazid (INH).DILI can be related to the genetic profile of the patient. Single nucleotide polymorphisms in the CYP2E1 gene and GSTM1...

Bacteriemia por Campylobacter jejuni en un paciente con infección por VIH en etapa SIDA

Rev. chil. infectol; 36 (5), 2019
Resumen La bacteriemia es una presentación atípica de la infección por Campylobacter jejuni, y es más frecuente en pacientes con inmunodepresión avanzada debido al VIH u otras enfermedades sistémicas. Debido a la terapia anti-retroviral, en las últimas décadas el número de casos ha disminuido. P...

Vulvar tuberculosis-A rare manifestation of the disease

Abstract Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. According to data from the World Health Organization, this disease remains one of the leading causes of death worldwide. Although it most commonly affects the lungs, tuberculosis can compromise any organ. The present stu...

Concentrations of rifampicin in pre-dose samples in patients with pulmonary tuberculosis

Braz. j. infect. dis; 23 (2), 2019
ABSTRACT Rifampicin is used in both phases of treatment for tuberculosis. In chronic use, the short half-life and the self-induction of metabolism can decrease the levels of the drug below the minimal inhibitory concentration. The aim of the study was to investigate whether plasma concentrations of rifam...

Fatores associados com o tabagismo em pacientes com tuberculose pulmonar

Rev. APS; 22 (1), 2019
Objetivo: identificar fatores associados ao tabagismo em pacientes com tuberculose (TB) pulmonar. Métodos: estudo transversal utilizando entrevista domiciliar com pacientes em tratamento para tuberculose pulmonar na Atenção Primária à Saúde em Campinas (SP), no período de 2013–2014. Foram inclu�...

Serum pyrazinamide concentrations in patients with pulmonary tuberculosis

J. bras. pneumol; 45 (2), 2019

A diagnosis of pulmonary tuberculosis and drug resistance among inmates in Mato Grosso do Sul, Brazil

Abstract INTRODUCTION: High endemic levels of pulmonary tuberculosis in prisons result from overcrowding, limited access to healthcare, delayed diagnosis, sustained transmission owing to poor control measures, and multidrug resistance. This study evaluated locally implemented measures for early pulmona...