ABSTRACT Objective: To understand the epidemiological and clinical profile of snakebite victims in a public teaching hospital. Method: Exploratory, descriptive, cross-sectional study with a quantitative approach conducted in a public hospital in the Triângulo Sul region of Minas Gerais state, Brazil. ...
Resumen : Introducción. El envenenamiento por mordedura de serpiente es considerado por la Organización Mundial de la Salud (OMS) una enfermedad tropical desatendida. Si bien los venenos de otras serpientes Bothrops se vienen estudiado ampliamente, poco se conoce del de Bothrops roedingeri. Objetivos....
Abstract Human envenomation by the snakes Colubridae and Dipsadidae are reported in Brazil, and envenomation by the Opisthoglyphous snake Philodryas olfersii could be dangerous. Here, we present the second record of an envenomation by Philodryas olfersii in Pernambuco, northeast Brazil. The male victim p...
Pathogenesis of Bothrops envenomations is complex and despite numerous studies on the effects of this snake venom on various biological systems, relatively little is known about such effects on the male reproductive system. In the present study, the toxicological outcomes of the low molecular weight frac...
Lee, Chi-Hsin;
Liu, Chia-I;
Leu, Sy-Jye;
Lee, Yu-Ching;
Chiang, Jen-Ron;
Chiang, Liao-Chun;
Mao, Yan-Chiao;
Tsai, Bor-Yu;
Hung, Ching-Sheng;
Chen, Chi-Ching;
Yang, Yi-Yuan.
The venom of bamboo vipers (Trimeresurus stejnegeri - TS), commonly found in Taiwan, contains deadly hemotoxins that cause severe envenomation. Equine-derived antivenom is a specific treatment against snakebites, but its production costs are high and there are some inevitable side effects. The aim of the...
Hatakeyama, Daniela Miki;
Tasima, Lídia Jorge;
Bravo-Tobar, Cesar Adolfo;
Serino-Silva, Caroline;
Tashima, Alexandre Keiji;
Rodrigues, Caroline Fabri Bittencourt;
Aguiar, Weslei da Silva;
Galizio, Nathália da Costa;
Lima, Eduardo Oliveira Venancio de;
Kavazoi, Victor Koiti;
Gutierrez-Marín, Juan David;
Farias, Iasmim Baptista de;
SantAnna, Sávio Stefanini;
Grego, Kathleen Fernandes;
Morais-Zani, Karen de;
Tanaka-Azevedo, Anita Mitico.
Variability in snake venoms is a well-studied phenomenon. However, sex-based variation of Bothrops atrox snake venom using siblings is poorly investigated. Bothrops atrox is responsible for the majority of snakebite accidents in the Brazilian Amazon region. Differences in the venom composition of Bothrop...
Kodama, Roberto Tadashi;
Kuniyoshi, Alexandre Kazuo;
Silva, Cristiane Castilho Fernandes da;
Cajado-Carvalho, Daniela;
Duzzi, Bruno;
Mariano, Douglas Ceolin;
Pimenta, Daniel C;
Borges, Rafael;
Silva, Wilmar Dias da;
Portaro, Fernanda Calheta Vieira.
Proteases play an important role for the proper physiological functions of the most diverse organisms. When unregulated, they are associated with several pathologies. Therefore, proteases have become potential therapeutic targets regarding the search for inhibitors. Snake venoms are complex mixtures of m...
Dong, Degang;
Deng, Zhongping;
Yan, Zhangren;
Mao, Wenli;
Yi, Jun;
Song, Mei;
Li, Qiang;
Chen, Jun;
Chen, Qi;
Liu, Liang;
Wang, Xi;
Huang, Xiuqin;
Wang, Wanchun.
Snakebites remain a major life-threatening event worldwide. It is still difficult to make a positive identification of snake species by clinicians in both Western medicine and Chinese medicine. The main reason for this is a shortage of diagnostic biomarkers and lack of knowledge about pathways of venom-i...
Snake venom phospholipases A2 (svPLA2) are biologically active toxins, capable of triggering and modulating a wide range of biological functions. Among the svPLA2s, crotoxin (CTX) has been in the spotlight of bioprospecting research due to its role in modulating immune response and hemostasis. In the pre...
Boda, Francisc;
Banfai, Krisztina;
Garai, Kitti;
Kovacs, Bela;
Almasi, Attila;
Scheffer, Dalma;
Sinkler, Reka Lambertne;
Csonka, Robert;
Czompoly, Tamas;
Kvell, Krisztian.
Certain environmental toxins permanently damage the thymic epithelium, accelerate immune senescence and trigger secondary immune pathologies. However, the exact underlying cellular mechanisms and pathways of permanent immune intoxication remain unknown. The aim of the present study was to demonstrate gen...
