This study was set to investigate the effect of gum Arabic (G.A.) on diabetic kidney disease. We divided sixty male Sprague rats randomly into six groups. Normal control, normal rats treated with G.A., untreated diabetic rats, diabetic rats treated with insulin, diabetic rats treated with G.A., and diabe...
Nefropatías Diabéticas/prevención & control,
Goma Arábiga/administración & dosificación,
Goma Arábiga/farmacología,
Nefropatías Diabéticas/patología,
Diabetes Mellitus Experimental/complicaciones,
Diabetes Mellitus Experimental/patología,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Estrés Oxidativo/efectos de los fármacos,
Antioxidantes/administración & dosificación,
Antioxidantes/farmacología,
Ratas Sprague-Dawley,
Riñón/efectos de los fármacos,
Inyecciones Intraperitoneales
Acetaminophen (also called paracetamol, or APAP) causes acute kidney injury after accidental or intentional ingestion of a toxic dose of the drug. We tested whether the antioxidant and anti-inflammatory agent, quercetin (QUR) given alone can protect against acute nephrotoxicity induced by APAP overdose i...
Lesión Renal Aguda/inducido químicamente,
Acetaminofén/toxicidad,
Quercetina/administración & dosificación,
Quercetina/farmacología,
Modelos Animales de Enfermedad,
Biomarcadores/análisis,
Estrés Oxidativo/efectos de los fármacos,
Riñón/efectos de los fármacos,
Sustancias Protectoras,
Antioxidantes/administración & dosificación,
Antioxidantes/farmacología,
Creatinina,
Inflamación
Abstract Background Telogen effluvium is the most common form of non-scarring alopecia characterized by diffuse hair loss. Ischemia-modified albumin is a marker of oxidative stress and inflammation. Objective The aim of this study was to compare the levels of ischemia-modified albumin of telogen effluv...
Abstract Introduction Tinnitus is defined as the perception of sound in the head or in the head in the absence of external sounds. The cause of tinnitus is still unknown. Objective We aimed to compare the serum levels of total oxidant status, total antioxidant status, serum prolidase enzyme activity an...
Sánchez Martínez, Concepción;
Torres González, Liliana;
Alarcón Galván, Gabriela;
Muñoz Espinosa, Linda E;
Zapata Chavira, Homero;
Moreno Peña, Diana Patricia;
Náñez Terreros, Homero;
Pérez Rodríguez, Edelmiro;
Garza Ocañas, Lourdes;
Guzmán de la Garza, Francisco Javier;
Cordero Pérez, Paula Andrea.
Introduction: Essential amino acid α-keto acid analogs are used in the treatment of chronic kidney disease to delay the symptoms of uremia. However, it is unknown whether essential amino acid α-keto acid analogs affect the oxidative stress and the inflammation in acute renal injury such as those produc...
Abstract Background: Although not fully understood, oxidative stress has been implicated in the pathogenesis of different autoimmune diseases such as systemic sclerosis. Accumulating evidence indicates that oxidative stress can induce mitochondrial DNA (mtDNA) damage and variations in mtDNA copy number ...
Estudios de Casos y Controles,
Variaciones en el Número de Copia de ADN,
Daño del ADN,
ADN Mitocondrial/sangre,
ADN Mitocondrial/genética,
Electroforesis en Gel de Agar,
Persona de Mediana Edad,
Estrés Oxidativo/genética,
Especies Reactivas de Oxígeno/sangre,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Esclerodermia Sistémica/sangre,
Esclerodermia Sistémica/genética,
Estadísticas no Paramétricas
RESUMEN La N-acetilcisteína es conocida en varias especialidades médicas. Su empleo en cardiología se ha incrementado desde hace décadas, por su potencial para disminuir el impacto del daño por reperfusión en el infarto miocárdico agudo. Pero el espectro de sus efectos es aún mayor, tiene accione...
High intake of omega-3 fatty acids has been associated with synaptic plasticity, neurogenesis and memory in several experimental models. To assess the efficacy of fish oil supplementation on oxidative stress markers in patients diagnosed with probable Alzheimer´s disease (AD) we conducted a double blind...
Introduction: Periodontitis affects more than 20% of the Latin American population. Oxidative markers are associated with greater progression of periodontitis; therefore, its role in pathogenesis should be studied. Objective: To determine the prevalence of the main oral bacteria and viruses associated wi...
