Results: 410

Impact of C4, C4A and C4B gene copy number variation in the susceptibility, phenotype and progression of systemic lupus erythematosus

Adv Rheumatol; 59 (), 2019
Abstract Background Complement component 4 (C4) gene copy number (GCN) affects the susceptibility to systemic lupus erythematosus (SLE) in different populations, however the possible phenotype significance remains to be determined. This study aimed to associate C4A , C4B and total C4 GCN and SLE, focusi...

Nailfold capillaroscopy as a risk factor for pulmonary arterial hypertension in systemic lupus erythematosus patients

Adv Rheumatol; 59 (), 2019
Abstract Background: Pulmonary arterial hypertension (PAH) is a rare and severe complication of systemic lupus erythematosus (SLE). This study aimed to evaluate clinical and laboratory risk factors associated with PAH in SLE patients. Methods: This was a retrospective case-control study in which patien...

The effect of therapies on the quality of life of patients with systemic lupus erythematosus: a meta-analysis of randomized trials

Adv Rheumatol; 59 (), 2019
Abstract Introduction Systemic lupus erythematosus (SLE) is a multi-systemic, chronic inflammatory disease of autoimmune nature, which can impair performance in daily life activities, causing to a compromised quality of life. Thus, the aim of this study was to evaluate the effect of therapies, such as ...

Altered peripheral lymphocyte subsets in untreated systemic lupus erythematosus patients with infections

Braz. j. med. biol. res; 52 (4), 2019
The leading cause of death in systemic lupus erythematosus (SLE) patients is infection. The objective of this study was to evaluate the distribution of lymphocyte subsets in untreated SLE patients with infections. This was a cross-sectional study. Data from January 2017 to May 2018 were collected. Flow c...

Lupus eritematoso sistémico: datos sociodemográficos y su correlación clínico-analítica en un hospital universitario
Systemic Lupus Erythemathosus: sociodemographic data and clinical correlation at an university hospital

Objetivos: Analizar las características sociodemográficas y clínicas de los pacientes con Lupus Eritematoso Sistémico (LES) del Servicio de Reumatología de un Hospital Universitario de Córdoba. Pacientes y métodos: Estudio retrospectivo, descriptivo y analítico de 303 pacientes adultos con LES as...

Poliadenopatías mediastinales y diagnósticos diferenciales en lupus eritematoso sistémico. Reporte de un caso y revisión de la literatura
Mediastinal polyadenopathies and differential diagnoses in systemic lupus erythematosus. Case report and literature review

Paciente varón de 59 años de edad con diagnóstico de lupus eritematoso sistémico y cuadro de consolidación pulmonar asociada a poliadenopatías mediastinales y derrame pleural, con evolución crónica y tórpida. Se discuten diagnósticos diferenciales e implicancia clínica...

Síndrome de encefalopatía posterior reversible en lupus eritematoso sistémico
Reversible posterior encephalopathy syndrome in systemic lupus erythematosus

El síndrome de encefalopatía posterior reversible (PRES) es una condición reversible, poco conocida en el lupus eritematoso sistémico (LES) que puede semejar al lupus neuropsiquiátrico. Las manifestaciones de PRES son cefalea, convulsiones, alteración del nivel de conciencia y amaurosis. En la mayo...

Análisis bibliométrico de la investigación en lupus eritematoso sistémico en Colombia

Objetivo: Realizar un estudio bibliométrico de la producción científica en lupus eritematoso sistémico en Colombia que describa su distribución, tendencia de desarrollo, patrón de colaboraciones nacionales e internacionales, y su impacto en la comunidad científica. Fecha y lugar de ejecución del ...

Altered Tregs and oxidative stress in pregnancy associated lupus

Adv Rheumatol; 59 (), 2019
Abstract Aim SLE is a systemic autoimmune disease generally affecting woman in the reproductive age. It is associated with an altered level of Tregs and oxidative stress while an increase in Tregs, and different antioxidant mechanisms to combat oxidative stress are essential for successful pregnancy. H...

Psychoanalytic psychotherapy improves quality of life, depression, anxiety and coping in patients with systemic lupus erythematosus: a controlled randomized clinical trial

Adv Rheumatol; 59 (), 2019
Abstract Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease which impairs the quality of life. The objective of study was to evaluate the effectiveness of Brief Group Psychoanalytic Psychotherapy to improve quality of life, depression, anxiety and coping strategies in SLE patients. ...