Jozala, Angela Faustino;
Geraldes, Danilo Costa;
Tundisi, Louise Lacalendola;
Feitosa, Valker de Araújo;
Breyer, Carlos Alexandre;
Cardoso, Samuel Leite;
Mazzola, Priscila Gava;
Oliveira-Nascimento, Laura de;
Rangel-Yagui, Carlota de Oliveira;
Magalhães, Pérola de Oliveira;
Oliveira, Marcos Antonio de;
Pessoa Jr, Adalberto.
ABSTRACT The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant growth in the production and approval of recombinant proteins such as interfer...
Sobreira Dantas Nóbrega de Figuêiredo, Francisco Rodolpho;
Gyllyandeson, de Araújo Delmondes;
Paulo da Cruz, Luzia;
Amaro do Nascimento, Érika;
Relison Tintino, Saulo;
Santiago Lemos, Izabel Cristina;
Bezerra da Cunha, Francisco Assis;
Vega Gomez, Maria Celeste;
Coronel, Cathia;
Martins da Costa, José Galberto;
Melo Coutinho, Henrique Douglas;
Bezerra Felipe, Cícero Francisco;
Alencar de Menezes, Irwin Rose;
Kerntopf, Marta Regina.
As doenças parasitárias, também chamadas de “doenças negligenciadas”, continuam sendo uma grande dificuldade para o desenvolvimento social e econômico dos países mais pobres. Podemos citar como exemplo dessas doenças, a leishmaniose e a doença de Chagas. A leishmaniose é causada por ...
Enfermedades Desatendidas/epidemiología,
Enfermedades Desatendidas/terapia,
Extractos Vegetales/uso terapéutico,
Productos Biológicos/uso terapéutico,
Estudios de Evaluación como Asunto,
Enfermedad de Chagas/epidemiología,
Enfermedad de Chagas/terapia,
Leishmaniasis/epidemiología,
Leishmaniasis/terapia,
Annonaceae,
Annona/toxicidad,
Fitoterapia,
Preparaciones de Plantas/uso terapéutico
ABSTRACT Polymeric stabilizers have received attention in the preparation of nanostructured systems due to their ability to enhance formulation stability. Considering this, the objective of this work was to prepare poly(ε-caprolactone) nanocapsules using the pullulan as a polymeric stabilizer. The n...
Graziola, Fabiana;
Candido, Thalita Marcílio;
Oliveira, Camila Areias de;
Peres, Daniela D'Almeida;
Issa, Michele Georges;
Mota, Joana;
Rosado, Catarina;
Consiglieri, Vladi Olga;
Kaneko, Telma Mary;
Velasco, Maria Valéria Robles;
Baby, André Rolim.
ABSTRACT Glutaraldehyde (GTA) has been extensively used as a gelatin crosslinking agent, however, new natural ones have been suggested as more biocompatible. Polyphenols are possible candidates and the flavonols, such as rutin (RUT), also exhibit potential synergism with sunscreens and antioxidant agents...
Background: In 2014, apple production in EU countries amounted to 11.8 million tonnes. A constant increase in the production of these fruits will lead to the accumulation of thousands of tonnes of apple pomace (production waste). The amount of industrial apples is the highest - their proportiononthe mark...
Objetivo: Estimar o custo por resposta dos medicamentos biológicos no tratamento da psoríase
moderada a grave sob as perspectivas do Sistema de Saúde Suplementar (SSS) e Sistema Único de
Saúde (SUS), representado pela Secretaria de Estado da Saúde de São Paulo, no Brasil. Métodos:
Quatro medicame...
Los productos naturales han sido la fuente más representativa en la obtención de agentes terapéuticos para el tratamiento del cáncer y su enorme contribución se reconoce en el descubrimiento de nuevas moléculas citotóxicas con variados mecanismos de acción. La mayoría de medicamentos utilizados ...
ABSTRACT PURPOSE: To investigate the potential efficacy of beractant (Survanta(r)) and Seprafilm(r) on the prevention of postoperative adhesions. METHODS: Forty Wistar-albino female rats were used. The rats were randomly allocated into four groups of 10 rats each as control group (CG), beractant group ...
Productos Biológicos/farmacología,
Enfermedades del Ciego/prevención & control,
Ciego/efectos de los fármacos,
Ácido Hialurónico/farmacología,
Ciego/patología,
Ciego/cirugía,
Quimioterapia Combinada/métodos,
Fibrosis,
Inflamación/patología,
Inflamación/prevención & control,
Modelos Animales,
Peritoneo/efectos de los fármacos,
Peritoneo/patología,
Cuidados Posoperatorios/instrumentación,
Distribución Aleatoria,
Ratas Wistar,
Adherencias Tisulares/patología,
Adherencias Tisulares/prevención & control
In the marine environment, all hard surfaces including marine macroorganims are colonized by microorganisms mainly from the surrounding environment. The microorganisms associated with marine macroorganisms offer tremendous potential for exploitation of bioactive metabolites. Biofouling is a continuous pr...
