Results: 22659

Determination of amphotericin B in PLA-PEG blend nanoparticles by HPLC-PDA

Braz. j. pharm. sci; 50 (4), 2014
In this work, we developed and validated an effective reversed-phase HPLC method with photodiode array (PDA) detection for the quantitative analysis of amphotericin B (AmB) in poly(lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles. Chromatographic runs were performed on a reverse phase C18 col...

Indicaciones no tradicionales de amigdalectomía. Actualización
Non-traditional indications of tonsillectomy. Upgrade

Tonsillectomy is the most common surgical procedure in ENT surgery. Indications are well known in the field. Upper airway obstruction caused by tonsilar hyperplasia and recurrent bacterial infections are the most frecuent indications of tonsillectomy, however there are many other pathologies where tonsil...

Experiência da escola de formação técnica em saúde na construção do currículo integrado por competências
Experience of the school of technical training in health in the construction of the curriculum integrated by competences

Capítulo tem como objetivo descrever o processo de construção do currículo integrado por competências no curso técnico em Enfermagem da EFTS-BA. Trata-se de uma pesquisa exploratória e descritiva, com abordagem qualitativa. as informações sobre o processo de construção do currículo integrado ...

Methanol extract from Vietnamese Caesalpinia sappan induces apoptosis in HeLa cells

Biol. Res; 47 (), 2014
BACKGROUND: This study evaluated the cytotoxic activity of extracts from Caesalpinia sappan heartwood against multiple cancer cell lines using an MTT cell viability assay. The cell death though induction of apoptosis was as indicated by DNA fragmentation and caspase-3 enzyme activation. RESULTS: A methan...

A robust HIV-1 viral load detection assay optimized for Indian sub type C specific strains and resource limiting setting

Biol. Res; 47 (), 2014
BACKGROUND: Human Immunodeficiency Virus Type 1 (HIV-1) viral load testing at regular intervals is an integral component of disease management in Acquired Immunodeficiency Syndrome (AIDS) patients. The need in countries like India is therefore an assay that is not only economical but efficient and highly...

The effects of cadmium chloride on secondary metabolite production in Vitis vinifera cv. cell suspension cultures

Biol. Res; 47 (), 2014
BACKGROUND: Plant secondary metabolites are possess several biological activities such as anti-mutagenic, anti-carcinogenic, anti-aging, etc. Cell suspension culture is one of the most effective systems to produce secondary metabolites. It is possible to increase the phenolic compounds and tocopherols by...

Pesticidal and pest repellency activities of rhizomes of Drynaria quercifolia (J. Smith) against Tribolium castaneum (Herbst)

Biol. Res; 47 (), 2014
BACKGROUND: Tribolium castaneum (Herbst) is a harmful pest of stored grain and flour-based products in tropical and subtropical region. In the present study, rhizome of Drynaria quercifolia (J. Smith) was evaluated for pesticidal and pest repellency activities against T. castaneum, using surface film met...

Loop-mediated isothermal amplification assays for screening of bacterial integrons

Biol. Res; 47 (), 2014
BACKGROUND: The occurrence and prevalence of integrons in clinical microorganisms and their role played in antimicrobial resistance have been well studied recently. As screening and detection of integrons are concerned, current diagnostic methodologies are restricted by significant drawbacks and novel me...

Proteomic analysis of the regenerating liver following 2/3 partial hepatectomy in rats

Biol. Res; 47 (), 2014
BACKGROUND: Liver regeneration (LR) after 2/3 partial hepatectomy (PH) is one of the most studied models of cell, organ, and tissue regeneration. Although the transcriptional profile analysis of regenerating liver has been carried out by many reserachers, the dynamic protein expression profile during LR ...

Biomarkers for screening of lung cancer and pre-neoplastic lesions in a high risk Chilean population

Biol. Res; 47 (), 2014
BACKGROUND: The mortality of lung cancer (LC), increases each year in the world, in spite of any advances, in development of new drugs to advance stages of LC. The high incidence of LC has been associated with smoking habit, genetic diversity and environmental pollution. Antofagasta region has been repor...