Results: 22652

Implante de segmentos de anel estromal em ceratocone: resultados e correlações com a biomecânica corneana pré-operatória

Rev. bras. oftalmol; 71 (2), 2012
OBJETIVO: Verificar os resultados da cirurgia de implante de segmentos de anel estromal para ceratocone e as possíveis correlações existentes entre o resultado cirúrgico e o estado biomecânico da córnea no pré-operatório. MÉTODOS: Dezenove olhos de 19 pacientes com ceratocone foram avaliados ant...

Relevância da biomecânica da córnea no glaucoma

Rev. bras. oftalmol; 71 (2), 2012
Relato de caso de uma paciente, com córnea espessa, por distrofia de Fuchs em fase inicial, ainda com transparência corneana preservada (edema corneano subclínico), associado à pressão intraocular (PIO) normal por tonometria de aplanação de Goldman (TAG), que teve entretanto, o diagnóstico de gla...

Avaliação da camada de fibras nervosas da retina nas afecções neuroftalmológicas da via óptica anterior

Rev. bras. oftalmol; 71 (2), 2012
A avaliação da camada de fibras nervosas da retina tem grande importância no diagnóstico e acompanhamento de várias afecções da via óptica anterior. Nesta revisão, discutiremos os principais métodos de análise clínica e instrumental da camada de fibras nervosas da retina e revisamos os princi...

Poly-ε -caprolactone microspheres containing interferon alpha as alternative formulations for the treatment of chronic hepatitis C

Braz. j. pharm. sci; 48 (1), 2012
Interferon-alpha (IFN-alpha) is one of the main drugs used in the treatment of hepatitis C. Use of IFN-alpha has some limitations that result in poor treatment efficacy and low patient compliance. Therefore, the aim of this study was to develop poly-ε-caprolactone (PCL) microspheres containing IFN-a...

Application of Comet assay to assess the effects of white bean meal on DNA of human lymphocytes

Braz. j. pharm. sci; 48 (1), 2012
This study was conducted to evaluate the potential induction of genotoxic effects of white bean flour using the Comet assay. The test was conducted with human lymphocytes present in whole blood immediately after collection, by incubation with white bean flour in three concentrations (3.92, 9.52 and 18.18...

Leaf and stem microscopic identification of Tithonia diversifolia (Hemsl.) A. Gray (Asteraceae)

Braz. j. pharm. sci; 48 (1), 2012
Tithonia diversifolia (Hemsl.) A. Gray is an Asteraceae shrub, popularly known as Mexican sunflower and cultivated for ornamental and therapeutic uses in different countries. In folk medicine, it is of value for treating diabetes, malaria and infectious diseases. These indications have been corroborated ...

Solubility enhancement, physicochemical characterization and formulation of fast-dissolving tablet of nifedipine-betacyclodextrin complexes

Braz. j. pharm. sci; 48 (1), 2012
The main objective of the study was to enhance the dissolution of nifedipine, a poorly water soluble drug by betacyclodextrin complexation and to study the effect of the preparation method on the in vitro dissolution profile. The stoichiometric ratio determined by phase solubility analysis for inclusion ...

HPLC method for the simultaneous determination of four compounds in rat plasma after intravenous administration of Portulaca oleracea L. extract

Braz. j. pharm. sci; 48 (1), 2012
The objective of the present study was to develop a simple and selective HPLC method for the simultaneous determination of hesperidin (HP), caffeic acid (CA), ferulic acid (FA) and p-coumaric acid (p-CA) in rat plasma after intravenous administration of Portulaca oleracea L. extract (POE). With the hyper...

Preoperative mechanical bowel preparation in elective colorectal surgery: an update of systematic review of the literature and meta-analysis

The belief that mechanical bowel preparation is related to the reduction of complications in elective colorectal surgery is based on observational studies and expert opinion. This question led the authors to a systematic literature review, with the completion of meta-analysis, followed by three updates. ...

Prototype of a computer system for managing data and video colonoscopy exams

OBJECTIVE: Develop a prototype using computer resources to optimize the management process of clinical information and video colonoscopy exams. MATERIALS AND METHODS: Through meetings with medical and computer experts, the following requirements were defined: management of information about medical profe...