Results: 467

Antiproliferative activity of biomass extract from Pseudomonas cedrina

Background: The study of plant-associated microorganisms is very important in the discovery and development of bioactive compounds. Pseudomonas is a diverse genus of Gammaproteobacteria comprising more than 60 species capable of establishing themselves in many habitats, which include leaves and stems of ...

Mortalidad a 30 días posterior a la administración de quimioterapia sistémica en una unidad oncológica regional

Rev. méd. Chile; 147 (7), 2019
Background: The use of systemic chemotherapy has survival and palliation benefits in oncological patients. Mortality at 30 days after the administration of systemic chemotherapy is considered as a quality and safety indicator of oncological patient care. The international mortality threshold is 5%, which...

Pericyte loss and detachment in experimental cisplatin-induced neuropathy

Int. j. morphol; 37 (2), 2019
Cisplatin is an antineoplastic agent with neuropathy as one of its major side effect. However, effective treatment is lacking. Increasing evidence suggests that cisplatin might damage nerve capillaries leading to impaired functions of blood-nerve barrier (BNB) and neuropathy. This study was aimed to exam...

Cardiotoxicidad de los quimioterapéuticos diferentes a antraciclinas de la lista oficial de medicamentosde la Caja Costarricense del Seguro Social

Rev. costarric. cardiol; 21 (1), 2019
Resumen La Cardio-oncología es una nueva disciplina que busca enfocarse en el tamizaje, monitoreo y tratamiento de los pacientes con cáncer que presentan enfermedad cardiaca durante o después de recibir tratamiento. Esto debido a que el efecto cardiotóxico asociado a los quimioterapéuticos es amplia...

Second brazilian consensus on the treatment of advanced prostate cancer: a SBOC-SBU-SBRT panel review

Int. braz. j. urol; 45 (3), 2019
ABSTRACT Prostate cancer is the second most common cancer and the fifth leading cause of cancer deaths. In Brazil, it is likewise the second most common cancer among men, second only to non-melanoma skin cancers. The aim of this consensus is to align different opinions and interpretations of the medical ...

In vivo and in vitro Pharmacological Evaluation of Gymnosporia Royleana

West Indian med. j; 68 (2), 2019
ABSTRACT Objective: Gymnosporia royleana (G royleana) Wall ex MA Lawson, locally known as (Sur Azghee), is traditionally used for the management of various diseases. In the current investigation, we made an effort to scientifically validate its traditional use in various pathological conditions, such as...

Astemizole, an inhibitor of ether-à-go-go-1 potassium channel, increases the activity of the tyrosine kinase inhibitor gefitinib in breast cancer cells

Rev. invest. clín; 71 (3), 2019
Abstract Background Expression and activity of the potassium channel ether-à-go-go-1 (EAG1) are strongly related to carcinogenesis and tumor progression, which can be exploited for therapeutic purposes. EAG1 activity may be reduced by preventing its phosphorylation with epidermal growth factor receptor...

La cardiooncología pediátrica como disciplina emergente en Cuba
Pediatric cardio-oncology as an emergent discipline in Cuba

Rev. cuba. pediatr; 91 (2), 2019
El reconocimiento inicial de la disfunción cardíaca ocasionada por estrategias terapéuticas aplicadas contra el cáncer fue realizado en la sexta década del siglo xx. La Cardiooncología es una nueva disciplina horizontal dirigida a la identificación de los pacientes en riesgo elevado para el desarr...

A case of chronic and relapsing paget disease of the vulva

Abstract Extramammary Paget disease is a rare neoplastic condition that more commonly affects postmenopausal Caucasian women. Although the vulvar area is the most frequently affected location, it corresponds solely to 1 to 2% of all vulvar malignancies. A 72-year-old female patient was observed in our ou...

Prevalencia y manejo de condilomas en población consultante en Chile: estudio "DIACON"

Rev. chil. infectol; 36 (3), 2019
Resumen Introducción: Los condilomas o verrugas genitales (VG) son la infección de transmisión sexual (ITS) más diagnosticada en los centros de ITS en Chile, pero no existen estadísticas poblacionales. Objetivos: Describir la prevalencia de VG en pacientes de 18-60 años que acuden a consulta ambu...