Experiments were conducted to determine if the follicle-stimulating hormone (FSH) receptor binding inhibitor (FRBI) impacts the expression levels of AT-rich interactive domain-containing protein 1A (ARID1A) and phosphatase and tensin homolog (PTEN) in ovaries and blood, as well as expressions of follicle...
Western Blotting,
Proteínas de Unión al ADN/sangre,
Proteínas de Unión al ADN/metabolismo,
Hormona Folículo Estimulante/metabolismo,
Proteínas Nucleares/sangre,
Proteínas Nucleares/metabolismo,
Neoplasias Ováricas/metabolismo,
Fosfohidrolasa PTEN/sangre,
Fosfohidrolasa PTEN/metabolismo,
Fosforilación,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Receptores de HFE/antagonistas & inhibidores,
Factores de Transcripción,
Activación Transcripcional/genética,
Regulación hacia Arriba
ABSTRACT Objective To evaluate the prevalence of G6PD deficiency and characterize G202A, A376G and C563T polymorphisms in neonates using molecular assays. Methods A total of one thousand samples were tested through quantitative analysis of enzyme activity, detecting 25 G6PD-deficient individuals. Patie...
Abstract The microbiological characterization by molecular techniques (DGGE and quantitative PCR) of Archaea, Bacteria domain and sulfate-reducing bacteria (SRB) from a laboratory scale Up-flow Anaerobic Sludge Blanket (UASB) processing sugar cane vinasse was performed during the operational phase with i...
Baicalein (BAI) is an acknowledged flavonoids compound, which is regarded as a useful therapeutic pharmaceutical for numerous cancers. However, its involvement in melanoma is largely unknown. This study aimed to examine the anti-melanoma function of BAI and unraveled the regulatory mechanism involved. A3...
Western Blotting,
Línea Celular Tumoral,
Movimiento Celular/efectos de los fármacos,
Proliferación Celular/efectos de los fármacos,
Regulación hacia Abajo/efectos de los fármacos,
Flavanonas/farmacología,
Regulación Neoplásica de la Expresión Génica/efectos de los fármacos,
Melanoma/patología,
Invasividad Neoplásica,
ARN Largo no Codificante/metabolismo,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
Fibroblast growth factor receptor 1 (FGFR1) has been reported in gastric cancer to be a prognostic factor. However, miR-497-targeted FGFR1 has not been explored in the carcinogenesis of gastric cancer. The present study intended to revalidate the prognostic significance of FGFR1 in patients with gastric ...
Apoptosis,
Western Blotting,
Línea Celular Tumoral,
Proliferación Celular,
Progresión de la Enfermedad,
Regulación Neoplásica de la Expresión Génica,
Inmunohistoquímica,
MicroARNs/metabolismo,
Pronóstico,
ARN Mensajero/genética,
ARN Mensajero/metabolismo,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Receptor Tipo 1 de Factor de Crecimiento de Fibroblastos/genética,
Receptor Tipo 1 de Factor de Crecimiento de Fibroblastos/metabolismo,
Transducción de Señal,
Neoplasias Gástricas/genética,
Neoplasias Gástricas/metabolismo,
Neoplasias Gástricas/patología
Abstract Pineapple (Ananas comosus var. comosus) fusariosis is an economically important fungal disease affecting the plant and its fruit. A rapid and reliable diagnosis is the base of integrated disease management practices. Fusariosis has resulted in quarantines for pineapple products in Central Americ...
Abstract Rabbit with hypercholesterolaemia is an important model for studying cholesterol metabolism disease. This study aimed to evaluate the expression stability of nine reference genes for quantitative PCR (qPCR) analysis in adrenal gland, liver, spleen, and kidney tissue from rabbits with hypercholes...
Objetivo: Avaliar a expressão do p16Ink4a por imunohistoquímica e a presença do HPV16 pela Real time PCR em tecido fresco, plasma e saliva de pacientes com leucoplasia bucal (LB) e hiperplasia fibrosa inflamatória (HFI). Material e métodos: Foram incluídos 67 pacientes com o diagnóstico de LB e 44...
Boca/patología,
Tabaquismo,
Hiperplasia,
Inmunohistoquímica,
Leucoplasia Bucal,
Mucosa Bucal,
Papillomaviridae,
Papillomavirus Humano 16,
Consumo de Bebidas Alcohólicas,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Boca/lesiones,
Genes p16
Abstract The aim of this study was to investigate the effects of low-intensity pulsed ultrasound (LIPUS) on the osteogenic differentiation of dental follicle cells (DFCs) in vitro and on the regenerative effects of DFC-OsteoBoneTM complexes in vivo. DFCs were isolated and characterized. In the in vitro s...
Regeneración Ósea/efectos de la radiación,
Cerámica,
Saco Dental/citología,
Saco Dental/efectos de la radiación,
Citometría de Flujo,
Ratones Desnudos,
Microscopía Electrónica de Rastreo,
Osteogénesis/efectos de la radiación,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Terapia por Ultrasonido/métodos,
Ondas Ultrasónicas
Abstract The aim of the present study was to identify the relationship between the expression of calcitonin gene-related peptide (CGRP) and the responses of pulp sensitivity tests in healthy pulps and irreversible pulps by performing a cross-sectional study on patients. Two hundred subjects were evaluate...
Péptido Relacionado con Gen de Calcitonina/análisis,
Estudios de Casos y Controles,
Estudios Transversales,
Pulpa Dental/patología,
Prueba de la Pulpa Dental/métodos,
Ensayo de Inmunoadsorción Enzimática,
Pulpitis/genética,
Pulpitis/patología,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Estadísticas no Paramétricas,
Factores de Tiempo
