SUMMARY: Doxorubicin is a drug that used by a majority in the treatment of carcinomas. The most obvious known side effect is cardiomyopathy. Many studies have been carried out to eliminate side effects of the doxorubicin, and stem cell studies have been added in recent years. In this study, it was aimed ...
SUMMARY: In order to evaluate the effect on sexual behavior and spermatic parameters of white New Zealand rabbits, at the onset of puberty, they were fed a standard diet supplemented with canola oil (obesogenic). Two groups were formed; one of which received daily 180 g of a standard commercial diet supp...
SUMMARY: Head trauma damages the optic nerve visual function and visual acuity.Effects of head trauma on the retina was investigated with biochemical, histological and immunohistochemical respects.The study was conducted on 30 rats with three groups: group 1 was control group (n=10). Second group was hea...
Enfermedades de la Retina/tratamiento farmacológico,
Enfermedades de la Retina/patología,
Lesiones Traumáticas del Encéfalo/patología,
Ácidos Cafeicos/administración & dosificación,
Retina/efectos de los fármacos,
Alcohol Feniletílico/análogos & derivados,
Alcohol Feniletílico/administración & dosificación,
Ratas Sprague-Dawley,
Inmunohistoquímica,
Glutatión Peroxidasa/análisis,
Malondialdehído/análisis,
Retina/patología
SUMMARY: Toxic effects of anti-cancer and other drugs on the normal tissues could be reduced by the herbal plants and their fractions. This study investigated the protective effect of Tribulus terrestris (TT) on Cisplatin- induced cytotoxicity germ cell apoptosis in male mice. In this experimental study,...
SUMMARY: Traumatic injury to the spinal cord results in the delayed dysfunction and neuronal death. Impaired mitochondrial function, generation of reactive oxygen species (ROS), and lipid peroxidation occur soon after traumatic spinal cord injury (SCI), while the activation of compensatory molecules that...
Reishi/química,
Fármacos Neuroprotectores/administración & dosificación,
Traumatismos de la Médula Espinal/tratamiento farmacológico,
Ratas Sprague-Dawley,
Traumatismos de la Médula Espinal/patología,
Inmunohistoquímica,
Etiquetado Corte-Fin in Situ,
Malondialdehído/análisis,
Glutatión/análisis,
Peroxidasa/efectos de los fármacos,
Estrés Oxidativo/efectos de los fármacos
SUMMARY: Retinoic acid, an active metabolite of vitamin A, plays essential signaling roles in mammalian embryogenesis. Prenatal rat fetuse exposure to retinoid induces some malformations in various organs, the most active and teratogenic metablolite is all-transretinoic acid (atRA). The teratogenic effec...
SUMMARY: An alternative superovulator to replace clomiphene citrate is needed as clomiphene citrate is associated with low pregnancy rates. Anastrozole is an effective superovulator, but it has not been well researched. In order to determine the effectiveness of anastrozole as a superovulator and to comp...
Nitrilos/farmacología,
Triazoles/farmacología,
Vinculina/efectos de los fármacos,
Integrinas/efectos de los fármacos,
Adhesiones Focales/efectos de los fármacos,
Microscopía Confocal,
Microscopía Fluorescente,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Útero/efectos de los fármacos,
Células Epiteliales/efectos de los fármacos,
Vinculina/fisiología,
Vinculina/genética,
Integrinas/fisiología,
Integrinas/genética,
Ratas Wistar
Summary Objective: To analyze the nutritional status of selenium and verify the effect of its supplementation in pediatric patients during 14 days of parenteral nutrition (PN). Method: This is a series of cases with patients followed for two weeks while using PN. Data collection was performed at the be...
Abstract Background: Anthracycline generates progressive left ventricular dysfunction associated with a poor prognosis. Objectives: The purpose of this study was to evaluate whether layer-specific strain analysis could assess the subclinical left ventricular dysfunction after exposure to anthracyclin...
Análisis de Varianza,
Antraciclinas/efectos adversos,
Antibióticos Antineoplásicos/efectos adversos,
Cardiotoxicidad/diagnóstico por imagen,
Cardiotoxicidad/etiología,
Estudios de Casos y Controles,
Estudios Transversales,
Ecocardiografía/métodos,
Epirrubicina/uso terapéutico,
Estudios de Seguimiento,
Corazón/efectos de los fármacos,
Corazón/fisiopatología,
Linfoma de Células B/tratamiento farmacológico,
Miocardio/patología,
Variaciones Dependientes del Observador,
Valores de Referencia,
Factores de Riesgo,
Estadísticas no Paramétricas,
Volumen Sistólico/efectos de los fármacos,
Volumen Sistólico/fisiología,
Disfunción Ventricular Izquierda/inducido químicamente,
Disfunción Ventricular Izquierda/diagnóstico por imagen,
Disfunción Ventricular Izquierda/fisiopatología
ABSTRACT BACKGROUND: Spontaneous bacterial peritonitis is a serious complication in cirrhotic patients, and changes in the microbiological characteristics reported in the last years are impacting the choice of antibiotic used for treatment. OBJECTIVE: The aim of the present study is to evaluate the ch...
Antibacterianos/farmacología,
Antibacterianos/uso terapéutico,
Profilaxis Antibiótica,
Brasil/epidemiología,
Farmacorresistencia Bacteriana/efectos de los fármacos,
Escherichia coli/efectos de los fármacos,
Escherichia coli/aislamiento & purificación,
Infecciones por Escherichia coli/tratamiento farmacológico,
Infecciones por Escherichia coli/epidemiología,
Bacterias Gramnegativas/efectos de los fármacos,
Bacterias Gramnegativas/aislamiento & purificación,
Bacterias Grampositivas/efectos de los fármacos,
Bacterias Grampositivas/aislamiento & purificación,
Infecciones por Bacterias Grampositivas/complicaciones,
Infecciones por Bacterias Grampositivas/tratamiento farmacológico,
Infecciones por Bacterias Grampositivas/epidemiología,
Cirrosis Hepática/complicaciones,
Pruebas de Sensibilidad Microbiana,
Peritonitis/tratamiento farmacológico,
Peritonitis/microbiología,
Estudios Retrospectivos,
Staphylococcus aureus/efectos de los fármacos,
Staphylococcus aureus/aislamiento & purificación,
Factores de Tiempo
