OBJECTIVES: To evaluate the effects of epoetin (EPO) alfa treatment on overall survival, event-free survival and response duration in patients with myelodysplastic syndrome (MDS) who were treated at a haematological referral centre in northeastern Brazil. METHODS: This was a retrospective cohort study o...
Transfusión Sanguínea,
Brasil,
Progresión de la Enfermedad,
Epoetina alfa/uso terapéutico,
Hematínicos/uso terapéutico,
Hemoglobinas/análisis,
Estimación de Kaplan-Meier,
Cariotipo,
Síndromes Mielodisplásicos/tratamiento farmacológico,
Síndromes Mielodisplásicos/mortalidad,
Recuento de Plaquetas,
Supervivencia sin Progresión,
Valores de Referencia,
Estudios Retrospectivos,
Factores de Riesgo,
Factores de Tiempo,
Resultado del Tratamiento
OBJECTIVES: Despite the number of surgical advances and innovations in techniques over time, radical vulvectomy frequently results in substantial loss of tissue that cannot be primarily closed without tension, the mobilization of surrounding tissues or even the rotation of myocutaneous flaps. The aim of ...
OBJECTIVE: To analyze our experience and learning curve for robotic pyeloplasty during this robotic procedure. METHODS: Ninety-nine patients underwent 100 consecutive procedures. Cases were divided into 4 groups of 25 consecutive procedures to analyze the learning curve. RESULTS: The median anastomosis...
Análisis de Varianza,
Pelvis Renal/cirugía,
Laparoscopía/educación,
Laparoscopía/métodos,
Curva de Aprendizaje,
Tiempo de Internación,
Tempo Operativo,
Complicaciones Posoperatorias,
Procedimientos Quirúrgicos Robotizados/educación,
Procedimientos Quirúrgicos Robotizados/métodos,
Estadísticas no Paramétricas,
Cirujanos/educación,
Resultado del Tratamiento,
Obstrucción Ureteral/cirugía
Qin, Jie;
Li, Jianjun;
Liu, Ying;
Zhao, Bo;
Dong, Hui;
Dong, Bo;
Zhang, Rui;
Ning, Ning;
Zhang, Xin;
Cui, Feng;
Li, Haopeng;
He, Xijing;
Wang, Dong.
OBJECTIVES: Osteoporotic vertebral compression fractures (OVCFs) affect the elderly population, especially postmenopausal women. Percutaneous kyphoplasty is designed to treat painful vertebral compression fractures for which conservative therapy has been unsuccessful. High-viscosity cement can be injecte...
OBJECTIVES: To evaluate the safety and efficacy of a novel bone cement-injectable cannulated pedicle screw augmented with polymethylmethacrylate in osteoporotic spinal surgery. METHODS: This study included 128 patients with osteoporosis (BMD T-score −3.2±1.9; range, −5.4 to -2.5) who underw...
Cementos para Huesos/uso terapéutico,
Cementoplastia/métodos,
Estudios de Seguimiento,
Vértebras Lumbares/diagnóstico por imagen,
Vértebras Lumbares/cirugía,
Osteoporosis/diagnóstico por imagen,
Tornillos Pediculares/efectos adversos,
Polimetil Metacrilato/uso terapéutico,
Complicaciones Posoperatorias/etiología,
Fracturas de la Columna Vertebral/diagnóstico por imagen,
Fracturas de la Columna Vertebral/cirugía,
Fusión Vertebral/métodos,
Tomografía Computarizada por Rayos X,
Resultado del Tratamiento
ABSTRACT Objective To evaluate the cost-effectiveness of the addition of chemotherapy or abiraterone to androgen deprivation. Methods We developed an analytical model to determine the cost-effectiveness of the addition of docetaxel or abiraterone versus androgen deprivation therapy alone. Direct and ...
Antagonistas de Andrógenos/economía,
Antagonistas de Andrógenos/uso terapéutico,
Androstenos/economía,
Androstenos/uso terapéutico,
Antineoplásicos Hormonales/economía,
Antineoplásicos Hormonales/uso terapéutico,
Protocolos de Quimioterapia Combinada Antineoplásica/economía,
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico,
Brasil,
Análisis Costo-Beneficio/métodos,
Docetaxel/economía,
Docetaxel/uso terapéutico,
Placebos/economía,
Placebos/uso terapéutico,
Supervivencia sin Progresión,
Neoplasias de la Próstata/tratamiento farmacológico,
Neoplasias de la Próstata/economía,
Neoplasias de la Próstata/mortalidad,
Años de Vida Ajustados por Calidad de Vida,
Valores de Referencia,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Resultado del Tratamiento
ABSTRACT Objective To define a predictive factor for pathologic complete response, compare the oncologic outcomes associated with the degree of pathologic response after neoadjuvant chemotherapy, and to analyze pathologic complete response as a prognostic factor for overall survival and progression-free...
Análisis de Varianza,
Neoplasias de la Mama/química,
Neoplasias de la Mama/tratamiento farmacológico,
Neoplasias de la Mama/mortalidad,
Neoplasias de la Mama/patología,
Carcinoma/química,
Carcinoma/tratamiento farmacológico,
Carcinoma/mortalidad,
Carcinoma/patología,
Supervivencia sin Enfermedad,
Estimación de Kaplan-Meier,
Persona de Mediana Edad,
Análisis Multivariante,
Terapia Neoadyuvante/métodos,
Valor Predictivo de las Pruebas,
Receptores de Estrógenos/análisis,
Receptores de Progesterona/análisis,
Valores de Referencia,
Estudios Retrospectivos,
Factores de Riesgo,
Factores de Tiempo,
Resultado del Tratamiento
ABSTRACT Objective: To determine whether pre-hospital statin use is associated with lower renal replacement therapy requirement and/or death during intensive care unit stay. Methods: Prospective cohort analysis. We analyzed 670 patients consecutively admitted to the intensive care unit of an academic t...
APACHE,
Lesión Renal Aguda/mortalidad,
Lesión Renal Aguda/terapia,
Proteína C-Reactiva/análisis,
Colesterol/sangre,
HDL-Colesterol/sangre,
HDL-Colesterol/efectos de los fármacos,
LDL-Colesterol/sangre,
LDL-Colesterol/efectos de los fármacos,
Creatinina/sangre,
Cuidados Críticos/métodos,
Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico,
Unidades de Cuidados Intensivos,
Tiempo de Internación,
Estudios Prospectivos,
Curva ROC,
Valores de Referencia,
Terapia de Reemplazo Renal/mortalidad,
Terapia de Reemplazo Renal/estadística & datos numéricos,
Reproducibilidad de los Resultados,
Factores de Riesgo,
Resultado del Tratamiento,
Triglicéridos/sangre
ABSTRACT Ligneous conjunctivitis is a rare form of chronic and recurrent bilateral conjunctivitis, in which thick membranes develop on the tarsal conjunctiva and on other mucosae. We report the case of a 55-year old female patient with bilateral ligneous conjunctivitis who was successfully treated with 5...
Abstract In a recent study, the treatment of different human cancer cell lines in vitro with ethylene diamine tetra-acetic acid (EDTA) showed a promising anticancer activity which could be a novel promising approach for cancer treatment. The aim of this study is to address the ability of EDTA to enhance ...
