Results: 1100

Avaliação de biomarcadores séricos e suas relações com marcadores de remodelamento cardíaco e da fibrose miocárdica na cardiopatia chagásica crônica
Assessment of serum biomarkers and their relationships with markers of cardiac remodeling and myocardial fibrosis in chronic chagasic heart disease

A cardiomiopatia chagásica crônica (CCC) é responsável pela maior morbidade e pelo pior prognóstico da doença de Chagas, além de ser a mais fibrosante das cardiopatias. Na doença de Chagas, predizer quais fatores se correlacionam com progressão da doença, morbidade e mortalidade constitui um de...

In vitro effects of sodium selenite supplementation on cell viability of different forms of Trypanosoma cruzi

Rev. patol. trop; 49 (2), 2020
Selenium is an essential trace element which, at adequate levels, presents different beneficial biological effects, such as cancer regression, tissue development and protection against oxidative damage. The positive effects of this element are related to the expression of selenoproteins and their ability...

Pharmaceutical care in the state of Ceará, Brazil: socioeconomic and demographic profile of patients with chagas disease attended in a referral center

Rev. patol. trop; 49 (4), 2020
The Pharmaceutical Care Service of the Chagas Disease Research Laboratory (LPDC), in the State of Ceará, Brazil, treats patients with Chagas disease (CD), characterized as a chronic, neglected disease that requires full patient follow-up. Objective: determine the socioeconomic and demographic profile of...

Insecticide Resistance Mechanisms in Triatoma infestans (Reduviidae: Triatominae): The Putative Role of Enhanced Detoxification and Knockdown Resistance (kdr) Allele in a Resistant Hotspot From the Argentine Chaco

J. med. entomol; 57 (3), 2020
Chagas disease affects around 6 million people in the world, and in Latin America, it is mainly transmitted by the kissing bug. Chemical control of the vector with pyrethroid insecticides has been the most frequently used tool to reduce the disease incidence. Failures of field control have been detected ...

Deltamethrin resistance in Chagas disease vectors colonizing oil palm plantations: implications for vector control strategies in a public health-agriculture interface

Parasit. vectors; 13 (163), 2020
Background: Triatomine bugs are responsible for the vectorial transmission of the parasite Trypanosoma cruzi, etiological agent of Chagas disease, a zoonosis afecting 10 million people and with 25 million at risk of infection. Several triatomine species of the genus Rhodnius have been found inhabiting pa...

A voluntary use of insecticide treated nets can stop the vector transmission of Chagas disease

Plos negl. trop. dis; 14 (11), 2020
One of the stated goals of the London Declaration on Neglected Tropical Diseases is the interruption of domiciliary transmissions of Chagas disease in the region of the Americas. We used a game-theoretic approach to assess the voluntary use of insecticide treated nets (ITNs) in the prevention of the spre...

A study of the effects of imidacloprid under laboratory and field conditions on nymphs of Triatoma infestans (Hemiptera: Reduviidae)

Vet. parasitol; 280 (), 2020
The aim of this study was to determine imidacloprid’s lethal activity against fifth-instar nymphs of Triatoma infestans. In the first stage of this work, it was assayed the topical application of this insecticide on non-fed and repletion-fed nymphs. Results showed a DL50 three times greater in non-fed ...

Resistance to deltamethrin in Triatoma infestans: microgeographical distribution, validation of a rapid detection bioassay and evaluation of a fumigant canister as control alternative strategy

CambridgeCore; 110 (5), 2020
Triatoma infestans (Klug) (Hemiptera: Reduviidae) is the main vector of Chagas disease in the Southern Cone of America and resistance to pyrethroid insecticides has been detected in several areas from its geographical distribution. Pyrethroid resistance presents a complex geographical pattern at differen...

Genetic structure of deltamethrin-resistant populations of Triatoma infestans (Hemiptera: Reduviidae) in the Gran Chaco

SpringerLink; 119 (), 2020
The genetic structure of natural populations offers insight into the complexities of their dynamics, information that can be relevant to vector control strategies. Microsatellites are useful neutral markers to investigate the genetic structure and gene flow in Triatoma infestans, one of the main vectors ...

First report of the lethal activity and synergism between deltamethrin, amitraz and piperonyl butoxide against susceptible and pyrethroid-resistant nymphs of Triatoma infestans

Exp. parasitol; 218 (), 2020
In South America, Triatoma infestans (Hemiptera: Reduviidae) is the main vector of the parasite Trypanosoma cruzi, etiological agent of Chagas disease. The main strategy for vector control is to spray domestic structures with pyrethroids. Reports of populations of T. infestans with varying degrees of res...