ABSTRACT Introduction: The matrix metalloproteinase-7 (MMP-7) gene -181A>G polymorphism has been reported to be associated with colorectal cancer (CRC) and gastric cancer (GC) susceptibility, yet the results of these previous results have been inconsistent or controversial. Aim: To elaborate a meta-...
Norero, Enrique;
Vargas, Catalina;
Achurra, Pablo;
Ceroni, Marco;
Mejia, Ricardo;
Martinez, Cristian;
Munõz, Rodrigo;
Gonzalez, Paulina;
Calvo, Alfonso;
Díaz, Alfonso.
ABSTRACT Background: Laparoscopic gastrectomy has numerous perioperative advantages, but the long-term survival of patients after this procedure has been less studied. Aim: To compare survival, oncologic and perioperative outcomes between completely laparoscopic vs. open gastrectomy for early gastric c...
Chile,
Detección Precoz del Cáncer,
Gastrectomía/efectos adversos,
Gastrectomía/métodos,
Gastrectomía/mortalidad,
Estimación de Kaplan-Meier,
Laparoscopía/efectos adversos,
Laparoscopía/métodos,
Laparoscopía/mortalidad,
Escisión del Ganglio Linfático/mortalidad,
Estadificación de Neoplasias,
Periodo Perioperatorio,
Complicaciones Posoperatorias,
Estudios Retrospectivos,
Estadísticas no Paramétricas,
Neoplasias Gástricas/mortalidad,
Neoplasias Gástricas/patología,
Neoplasias Gástricas/cirugía,
Tasa de Supervivencia,
Factores de Tiempo,
Resultado del Tratamiento
ABSTRACT Introduction: A series of studies have evaluated the association between -592A>C and -819T>C polymorphisms in the promoter regions of Interleukin-10 (IL-10) and gastric cancer (GC) risk. However, the results remain inconclusive. Objective: To better understand the association of the poly...
ABSTRACT Background : It is believed that the Wnt pathway is one of the most important signaling involved in gastric carcinogenesis. Aim : To analyze the protein expression of canonical and non-canonical Wnt pathways in gastric carcinoma. Method : The immunohistochemistry was performed in 72 specimen...
Proteína Axina/análisis,
Carcinogénesis,
Carcinoma/química,
Carcinoma/patología,
Quinasa de la Caseína I/análisis,
Ciclina D1/análisis,
Receptores Frizzled/análisis,
Glucógeno Sintasa Quinasa 3 beta/análisis,
Inmunohistoquímica,
Proteínas de Neoplasias/análisis,
Estadificación de Neoplasias,
Proteínas Proto-Oncogénicas c-myc/análisis,
Valores de Referencia,
Neoplasias Gástricas/química,
Neoplasias Gástricas/patología,
Ubiquitina/análisis,
Vía de Señalización Wnt,
Proteína Wnt-5a/análisis
Introdução: A interdisciplinaridade é vista como uma alternativa que, somada ao desenvolvimento tecnológico, possa a contribuir para a melhoria do cuidado em saúde, mas cuja construção é cercada de desafios. O Grupo de Estudos e Tratamento do Câncer Gástrico e Esofágico de um hospital referên...
RESUMO Objetivo: comparar o polimorfismo dos genes Glutationa S-transferase teta 1 (GSTT1) e Glutationa S-transferase mu 1 (GSTM1) da área do tumor com as margens proximal e distal de espécimes de estômago ressecados de pacientes com câncer gástrico, e investigar a presença do DNA do vírus Epstei...
Adenocarcinoma/enzimología,
Adenocarcinoma/microbiología,
Adenocarcinoma/cirugía,
Adenocarcinoma/virología,
Genotipo,
Glutatión Transferasa/genética,
Helicobacter pylori/genética,
Helicobacter pylori/aislamiento & purificación,
Herpesvirus Humano 4/genética,
Herpesvirus Humano 4/aislamiento & purificación,
Persona de Mediana Edad,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético/genética,
Estudios Prospectivos,
Factores de Riesgo,
Neoplasias Gástricas/enzimología,
Neoplasias Gástricas/microbiología,
Neoplasias Gástricas/cirugía,
Neoplasias Gástricas/virología
Bartelli, Thais F;
Abrantes, Lais L Senda;
Freitas, Helano C;
Thomas, Andrew M;
Silva, Jordana M;
Albuquerque, Gabriela E;
Araújo, Luiza F;
Branco, Gabriela P;
Amorim, Maria G;
Serpa, Marianna S;
Takenaka, Isabella K T M;
Souza, Deborah T;
Monção, Lucas O;
Moda, Bruno S;
Valieris, Renan;
Defelicibus, Alexandre;
Borges, Rodrigo;
Drummond, Rodrigo D;
Alves, Francisco I A;
Santos, Monize N P;
Bobrovnitchaia, Irina G;
Elhaik, Eran;
Coelho, Luiz G V;
Khayat, André;
Demachki, Samia;
Assumpção, Paulo P;
Santiago, Karina M;
Torrezan, Giovana T;
Carraro, Dirce M;
Peres, Stela V;
Calsavara, Vinícius F;
Burbano, Rommel;
Nóbrega, Calebe R;
Baladão, Graziela P P B;
Pereira, Ana C C;
Gatti, Camila M;
Fagundes, Marcela A;
Araújo, Marília S;
Miranda, Tayana V;
Barbosa, Monica S;
Cardoso, Daniela M M;
Carneiro, Lilian C;
Brito, Alexandre M;
Ramos, Amanda F P L;
Silva, Lucas L L;
Pontes, Jaqueline C;
Tiengo, Tatiane;
Arantes, Paola E;
Santana, Vilma;
Cordeiro, Milena;
Sant’Ana, Rosane O;
Andrade, Hanna B;
Anaissi, Ana K M;
Sampaio, Sara V;
Abdallah, Emne A;
Chinen, Ludmilla T D;
Braun, Alexcia C;
Flores, Bianca C T;
Mello, Celso A L;
Claro, Laura C L;
Sztokfisz, Claudia Z;
Altamirano, Carlos C;
Carter, David R F;
Jesus, Victor H F;
Riechelmann, Rachel;
Medina, Tiago;
Gollob, Kenneth J;
Martins, Vilma R;
Setúbal, João C;
Pelosof, Adriane G;
Coimbra, Felipe J;
Costa-Jr, Wilson L;
Silva, Israel T;
Nunes, Diana N;
Curado, Maria P;
Dias-Neto, Emmanuel.
Gastric cancer (GC) is the fifth most common type of cancer worldwide with high incidences in Asia, Central, and
South American countries. This patchy distribution means that GC studies are neglected by large research centers from developed countries. The need for further understanding of this complex di...
Chen, Tingting;
Wang, Yong;
Yang, Yang;
Yu, Kaikai;
Cao, Xiangliao;
Su, Fang;
Xu, Huanbai;
Peng, Yongde;
Hu, Yudong;
Qian, Feng;
Wang, Zishu.
BACKGROUND: Gastric cancer is a common malignant tumor with high morbidity and mortality worldwide, which seriously affects human health. Gramicidin is a short peptide antibiotic which could be used for treating infection induced by bacteria or fungi. However, the anti-cancer effect of gramicidin on gast...
Apoptosis/efectos de los fármacos,
Ciclo Celular/efectos de los fármacos,
Movimiento Celular/efectos de los fármacos,
Proliferación Celular/efectos de los fármacos,
Gramicidina/farmacología,
Neoplasias Gástricas/patología,
Ciclina D1/efectos de los fármacos,
Ciclina D1/metabolismo,
Proteína Forkhead Box O1/efectos de los fármacos,
Proteína Forkhead Box O1/metabolismo,
Proteínas Proto-Oncogénicas c-bcl-2/efectos de los fármacos,
Proteínas Proto-Oncogénicas c-bcl-2/metabolismo,
Línea Celular Tumoral,
Regulación hacia Abajo,
Fosforilación
Introdução: O câncer de estômago é um dos tipos de neoplasias mais graves no mundo, apresentando alta incidência e mortalidade. Objetivo: Analisar a taxa de mortalidade por câncer de estômago entre os anos de 2000 e 2015 na Paraíba,Brasil. Material e Método: Trata-se d...
