Results: 262

Relevance of prognostic factors in the decision-making of stem cell transplantation in Myelodysplastic Syndromes

ABSTRACT The hematopoietic stem cell transplantation (HSCT) is the only curative alternative for Myelodysplastic Syndrome (MDS), but many patients are not eligible for this treatment, as there are several limiting factors, especially in the case of patients with low-risk MDS. The aim of this study is to ...

Association of oxidative stress and DNA damage with grafting time in patients with multiple myeloma and lymphoma submitted to autologous hematopoietic stem cell transplantation

ABSTRACT The aim of the study was to investigate the association between oxidative stress and DNA damage with grafting time in patients submitted to autologous hematopoietic stem-cell transplantation (HSCT). The study included 37 patients submitted to autologous HSCT diagnosed with Multiple Myeloma (MM) ...

Acute and chronic Graft-versus-host disease after hematopoietic stem cell transplantation

ABSTRACT graft-versus-host disease (GVHD) is one of the main complications of hematopoietic stem cell transplantation, affecting about 50% to 80% of the patients. Acute GVHD and its clinical manifestations are discussed in this article, as well as the new NIH criteria for the diagnosis and classification...

Allogenic bone narrow transplantation in sickle-cell diseases

SUMMARY Sickle-cell diseases are the most common inherited hemoglobinopathies worldwide. Improvement in survival has been seen in the last decades with the introduction of careful screening and prevention of complications and the introduction of hydroxyurea. Stem-cell transplantation is currently the onl...

Salud ósea en pacientes sometidos a trasplante de precursores hematopoyéticos: un nuevo problema a considerar

Rev. méd. Chile; 144 (9), 2016
Background: Patients undergoing hematopoietic cell transplantation (HCT) are at increased risk of developing osteoporosis. Aim: To determine the frequency and severity of Vitamin D deficiency, secondary hyperparathyroidism and low bone mass in patients undergoing HCT. Patients and Methods: Analysis of th...

Ajuste de intensidad para el trasplante hematopoyético alogénico en leucemia aguda

Rev. méd. Chile; 144 (9), 2016
Background: The intensity of conditioning chemotherapy and radiotherapy in hematopoietic stem cell transplantation (HSCT) varies according to several factors including the patient’s age, pre-existing conditions and performance status. Myeloablative conditioning (MA) increases transplant related mortalit...

Validación del índice de comorbilidad para trasplante hematopoyético en una cohorte retrospectiva de niños y adolescentes argentinos receptores de trasplante alogénico

Arch. argent. pediatr; 114 (4), 2016
Introducción. El trasplante hematopoyético es una terapia con riesgo de mortalidad relacionada con el trasplante (MRT), que puede variar según la comorbilidad previa. El índice de comorbilidad para trasplante hematopoyético (ICTH) es un instrumento desarrollado para medir este riesgo. Los reportes s...

Linfoma no hodgkiniano parecido al Burkitt

El linfoma no hodgkiniano parecido al Burkitt es considerado una neoplasia de células B altamente agresiva, con un alto índice de proliferación. Las presentaciones en forma de masas tumorales abdominales no son muy frecuentes y están poco documentadas en la literatura. Se reporta un caso poco usual d...

Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review

An. bras. dermatol; 91 (3), 2016
Abstract Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiolog...

A vivência do cuidado familiar em casas transitórias de apoio

Rev. bras. enferm; 69 (3), 2016
RESUMO Objetivo: apresentar modelo teórico representativo da vivência do cuidado em casas transitórias de apoio a familiares de crianças em pós-transplante de células-tronco hematopoiéticas. Método: Teoria Fundamentada nos Dados, realizada com 18 participantes de três grupos amostrais. Para an...