ABSTRACT Gallesia integrifolia (Phytolaccaceae) is native to Brazil and has a strong alliaceous odor. The objective of this study was to identify the chemical composition of G. integrifolia fruit essential oil and evaluate fungicidal activity against the main food-borne diseases and food spoilage fungi. ...
Aspergillus/efectos de los fármacos,
Aspergillus/crecimiento & desarrollo,
Brasil,
Frutas/química,
Fungicidas Industriales/química,
Fungicidas Industriales/farmacología,
Cromatografía de Gases y Espectrometría de Masas,
Pruebas de Sensibilidad Microbiana,
Aceites Volátiles/química,
Aceites Volátiles/farmacología,
Penicillium/efectos de los fármacos,
Penicillium/crecimiento & desarrollo,
Phytolaccaceae/química,
Aceites de Plantas/química,
Aceites de Plantas/farmacología
Abstract This study compares patients with and without non-viral microbial keratitis in relation to sociodemographic variables, clinical aspects, and involved causative agent. Clinical aspects, etiology and therapeutic procedures were assessed in patients with and without keratitis that were diagnosed in...
Antibacterianos/farmacología,
Antifúngicos/farmacología,
Bacterias/clasificación,
Bacterias/efectos de los fármacos,
Bacterias/genética,
Bacterias/aislamiento & purificación,
Infecciones Bacterianas/tratamiento farmacológico,
Infecciones Bacterianas/microbiología,
Brasil,
Hongos/clasificación,
Hongos/efectos de los fármacos,
Hongos/genética,
Hongos/aislamiento & purificación,
Queratitis/tratamiento farmacológico,
Queratitis/microbiología,
Persona de Mediana Edad,
Micosis/tratamiento farmacológico,
Micosis/microbiología
Platelet activating factor is a lipid mediator of inflammation, and in recent decades, it has emerged as an important factor in tumor outcomes. Platelet activating factor acts by specific binding to its receptor, which is present in both tumor cells and cells that infiltrate tumors. Pro-tumorigenic effec...
OBJECTIVES: Oxidative stress results from an imbalance between the generation and elimination of oxidant species. This condition may result in DNA, RNA and protein damage, leading to the accumulation of genetic alterations that can favor malignant transformation. Persistent infection with high-risk human...
Cell cycle control genes are frequently mutated in cancer cells, which usually display higher rates of proliferation than normal cells. Dysregulated mitosis leads to genomic instability, which contributes to tumor progression and aggressiveness. Many drugs that disrupt mitosis have been studied because t...
Cancer is a leading cause of death worldwide, and its incidence is continually increasing. Although anticancer therapy has improved significantly, it still has limited efficacy for tumor eradication and is highly toxic to healthy cells. Thus, novel therapeutic strategies to improve chemotherapy, radiothe...
OBJECTIVE: To correlate the perceptions related to dietary intake with the domains and subscales of health-related quality of life (HRQL) in women with breast neoplasms receiving chemotherapy. METHODS: In this prospective study, 55 women with breast cancer were followed up during chemotherapy at three d...
Análisis de Varianza,
Antineoplásicos/efectos adversos,
Apetito/efectos de los fármacos,
Neoplasias de la Mama/tratamiento farmacológico,
Neoplasias de la Mama/psicología,
Carcinoma Ductal de Mama/tratamiento farmacológico,
Carcinoma Ductal de Mama/psicología,
Carcinoma Lobular/tratamiento farmacológico,
Carcinoma Lobular/psicología,
Preferencias Alimentarias/efectos de los fármacos,
Preferencias Alimentarias/psicología,
Percepción/efectos de los fármacos,
Estudios Prospectivos,
Calidad de Vida/psicología,
Valores de Referencia,
Estadísticas no Paramétricas,
Factores de Tiempo
OBJECTIVES: Several compounds characterized by an olefin linkage conjugated to a carbonyl group have anti-inflammatory properties. The diuretic ethacrynic acid (EA) is a compound of this type. Herein, we tested the hypothesis that ethacrynic acid can modulate the development of ileus after bowel manipula...
Modelos Animales de Enfermedad,
Ácido Etacrínico/farmacología,
Tránsito Gastrointestinal/efectos de los fármacos,
Ileus/patología,
Ileus/cirugía,
Mediadores de Inflamación/antagonistas & inhibidores,
Interleucina-6/antagonistas & inhibidores,
Intestino Delgado/efectos de los fármacos,
Intestino Delgado/patología,
Ratones Endogámicos C57BL,
Óxido Nítrico Sintasa de Tipo II/antagonistas & inhibidores,
Complicaciones Posoperatorias,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
OBJECTIVES: Dietary omega-3 fatty acids have been efficacious in decreasing serum cholesterol levels and reducing the risk of cardiovascular disease. However, the metabolic and molecular changes induced by the omega-3 fatty acid α-linolenic acid (ALA), which is found in linseed oil, are not fully un...
Dieta Alta en Grasa,
Suplementos Dietéticos,
Estrés del Retículo Endoplásmico/efectos de los fármacos,
Ácidos Grasos Omega-3/administración & dosificación,
Ácidos Grasos Omega-3/farmacología,
Hígado Graso/prevención & control,
Prueba de Tolerancia a la Glucosa,
Inflamación/prevención & control,
Resistencia a la Insulina,
Ratones Endogámicos C57BL,
Ácido alfa-Linolénico/administración & dosificación,
Ácido alfa-Linolénico/farmacología
Low, Sandra Trindade;
Ferraz, Ana Paula Costa Rodrigues;
Maio, Regiane;
Francisqueti, Fabiane Valentini;
Pierine, Damiana Tortolero;
Borges, Weidylla Natália Silva;
Carvalho, Ariel Dandara de;
Lima, Gedalva Pereira de;
Ferreira, Ana Lúcia A;
dos Santos, Klinsmann Carolo;
Corrêa, Camila Renata.
OBJECTIVE: The aim of the present study was to investigate the association of the redox state via malondialdehyde (MDA) as a lipid peroxidation biomarker and hydrophilic antioxidant capacity (HAC) with dietary, anthropometric, demographic, socio-economic and clinical variables as well as the serum concen...
