INTRODUCCIÓN: La función tiroidea del prematuro se ve alterada por la relativa inmadurez del eje hipotálamo-hipófisis-tiroides, junto a otros factores como la incidencia de enfermedades o el uso de algunos fármacos. Actualmente existe controversia sobre los niveles normales de tiroxina libre (T4L) ...
INTRODUCCIÓN: El síndrome antifosfolípido es una trombofilia adquirida autoinmune, caracterizada por trombosis arteriales y/o venosas. En raras ocasiones este cuadro puede tener una presentación catastrófica, de elevada mortalidad, con presencia de microangiopatia y compromiso de tres o más órgan...
Summary Objective: Chronic hepatitis C (CHC) continues to be a critical problem. The liver fibrosis score is the most valuable tool in determining treatment and prognosis. Liver biopsy is still considered a gold method but, due to unmet needs, new non-invasive markers are required. The aim of this study...
Glomerular filtration rate (GFR) is the best approximation to global renal function and its estimation is of great relevance for clinical practice. Since the measurement of GFR by reference methods is complex, costly and not widely available, its routine evaluation is performed using endogenous biomarker...
ABSTRACT BACKGROUND: Celiac disease is an enteropathy caused by dietary gluten. The combination of serologic, genetic and histologic data has led to description of other categories of this disease. OBJECTIVE: There are a number of patients with iron deficiency anemia (IDA) that do not respond to iron t...
Anemia Ferropénica/sangre,
Anemia Ferropénica/complicaciones,
Anemia Ferropénica/terapia,
Autoanticuerpos/sangre,
Biomarcadores/sangre,
Biopsia,
Enfermedad Celíaca/sangre,
Enfermedad Celíaca/diagnóstico,
Enfermedad Celíaca/inmunología,
Enfermedad Celíaca/patología,
Estudios Transversales,
Duodeno/patología,
Mucosa Intestinal/patología,
Persona de Mediana Edad,
Estudios Prospectivos,
Pruebas Serológicas/métodos,
Transglutaminasas/sangre
Ventura, Julia Carvalho;
Hauschild, Daniela Barbieri;
Moreira, Emília Addison Machado;
Pereira, Letícia Cristina Radin;
Rosa, Anauã Franco;
Barbosa, Eliana;
Ludwig-Neto, Norberto;
Rosa, Julia Salvan da;
Fröde, Tânia Silvia;
Moreno, Yara Maria Franco.
ABSTRACT BACKGROUND: Chronic lung infections, inflammation and depletion of nutritional status are considered to be prognostic indicators of morbidity in patients with cystic fibrosis. The aim of this study was to investigate the association between inflammatory markers and lung function, nutritional s...
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Fibrosis Quística/sangre,
Fibrosis Quística/fisiopatología,
Mediadores de Inflamación/sangre,
Interleucina-1beta/sangre,
Estudios Longitudinales,
Estado Nutricional,
Peroxidasa/sangre,
Estudios Prospectivos,
Pruebas de Función Respiratoria,
Albúmina Sérica/análisis,
Factor de Necrosis Tumoral alfa/sangre
Abstract Purpose: To investigate thymoquinone, curcumin and a combination of these two drugs were effective or not at the growth of liver. Methods: Forty female Wistar-Albino rats distributed into five groups of eight rats each, control, thymoquinone, curcumin, and thymoquinone/curcumin groups. Pathol...
Antineoplásicos/farmacología,
Antioxidantes/farmacología,
Arginasa/sangre,
Benzoquinonas/farmacología,
Biomarcadores/sangre,
Proliferación Celular,
Ceruloplasmina/análisis,
Curcumina/farmacología,
Hepatectomía/métodos,
Antígeno Ki-67/análisis,
Hígado/patología,
Neoplasias Hepáticas/cirugía,
Regeneración Hepática/efectos de los fármacos,
Trasplante de Hígado,
Óxido Nítrico/sangre,
Ratas Wistar,
Activador de Tejido Plasminógeno/sangre
Summary Objective: To evaluate the carotid intima-media complex (CIMC) thickness and lipid metabolism biomarkers associated with cardiovascular risk (CR) in parents of patients with ataxia-telangiectasia and verify an association with gender. Method: A cross-sectional and controlled study with 29 ATM h...
Ataxia Telangiectasia/sangre,
Ataxia Telangiectasia/genética,
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Enfermedades Cardiovasculares/diagnóstico,
Arterias Carótidas,
Grosor Intima-Media Carotídeo,
Estudios de Casos y Controles,
HDL-Colesterol/sangre,
Estudios Transversales,
Heterocigoto,
Persona de Mediana Edad,
Estado Nutricional,
Padres,
Medición de Riesgo,
Factores de Riesgo,
Factores Sexuales
Abstract Objective: To compare the perioperative incidence rates of hemolysis and inflammatory response in patients undergoing coronary artery bypass grafting with the two main types of cardiopulmonary bypass, centrifugal and roller pumps, and establish correlations among hemolytic and inflammatory chan...
ABSTRACT Objective This study aimed to evaluate the association between different renal biomarkers with D-Dimer levels in diabetes mellitus (DM1) patients group classified as: low D-Dimer levels (< 318 ng/mL), which included first and second D-Dimer tertiles, and high D-Dimer levels (≥ 318 ng/m...
Albuminuria/etiología,
Albuminuria/fisiopatología,
Biomarcadores/sangre,
Creatinina/sangre,
Cistatina C/sangre,
Diabetes Mellitus Tipo 1/sangre,
Diabetes Mellitus Tipo 1/fisiopatología,
Nefropatías Diabéticas/sangre,
Nefropatías Diabéticas/fisiopatología,
Ensayo de Inmunoadsorción Enzimática,
Productos de Degradación de Fibrina-Fibrinógeno/análisis,
Tasa de Filtración Glomerular,
Pruebas de Función Renal,
Urea/sangre
